[show abstract][hide abstract] ABSTRACT: A selective C(3)-alkylation via activation/functionalization of sp(3) C-H bond of saturated cyclic amines was promoted by (arene)ruthenium(II) complexes featuring a bidentate phosphino-sulfonate ligand upon reaction with aldehydes. This highly regioselective sustainable transformation takes place via initial dehydrogenation of cyclic amines and hydrogen autotransfer processes.
Journal of the American Chemical Society 06/2011; 133(27):10340-3. · 10.68 Impact Factor
[show abstract][hide abstract] ABSTRACT: An unprecented N-and C(3)-dialkylation of unactivated amines by a cascade reaction via bor-rowing hydrogen methodology using new (arene)ru-thenium(II) complexes featuring phosphinosulfo-nate ligands is described. This reaction is highly re-gioselective and produces water as the only side product.
[show abstract][hide abstract] ABSTRACT: Selective N ,N-diallylation and N ,N, O-triallylation of free amino acids in the presence of catalytic amounts of RuCp*(MeCN)(3)PF(6) is reported. The crucial influence of the solvent makes these allylation reactions selectively possible.