-
[show abstract]
[hide abstract]
ABSTRACT: UK, Germany as well as the Council of Europe recommendation guide have set limits of RBC in clinical fresh frozen plasma (FFP), but current transfusion guidelines do not get the consensus opinion at recommending the D status of FFP to be considered before transfusion. We report a female group A, D- patient with cerebrovascular disease who was induced to develop IgG immune anti-D which can be detected on the 15th day of hospitalization after the relatively regular time interval of transfusion of 1800ml apheresis FFP. Therefore, in making clinical decisions to transfuse FFP or apheresis FFP, the best choice is considered as the same or compatibility with RhD group, in case Rh immunization can be induced and trigger some potential serious problems in future emergent transfusion or pregnancy, especially in high incidence of D antigen countries.
Transfusion Clinique et Biologique 09/2009; 16(4):400-3. · 0.80 Impact Factor
-
[show abstract]
[hide abstract]
ABSTRACT: The anti-tumour component (Fraction A) found in the culture filtrates of a local mushroom, Tricholoma sp. (strain STC20-T1), was purified using DEAE-cellulose ion exchange chromatography and Sepharose CL-4B gel filtration. Of its two purified sub-fractions, A-1 and A-2, only the latter showed anti-tumor activity. When Fraction A-2 was treated with cetyltrimethylammonium hydroxide and chloroform/butanol (24:1, v/v), it behaved as a proteinbound polysaccharide, with a molecular mass estimated to be 154 kDa by gel filtration. It contained 40% polysaccharide, which consisted of fucose, galactose, glucose, arabinose and mannose, and 30.5% protein, the amino-acid composition of which was determined. Fraction A-2 could inhibit the growth of Sarcoma-180 implanted in mice intraperitoneally and subcutaneously, with no sign of toxicity, at a dose of 20 mg/kg.day for 10 days.
World Journal of Microbiology and Biotechnology 01/1995; 11(5):486-490. · 1.53 Impact Factor
-
[show abstract]
[hide abstract]
ABSTRACT: 1.1. The polysaccharide-protein complex(PSPC) isolated from the culture filtrate of Tricholoma lobayense showed antitumor activity in mice.2.2. PSPC had the ability to restore the phagocytic function of peritoneal exudate cells (PEC) and T-cell mitogenic activity of tumor-bearing mice.3.3. An increase in the production of reactive nitrogen intermediates and tumor necrosis factor (TNF) was determined in PEC of mice that had received PSPC.4.4. The present study showed that PSPC both induced the various immune responses in vivo and exhibited cytotoxicity against tumor cell lines in the presence of PSPC at doses of 30 and 60 μ/ml in vitro.
General Pharmacology: The Vascular System.
