Publications (2)0 Total impact
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Article: [Hemodynamic changes of pregnant rats with pre-eclampsia after treatment with low-energy laser irradiation of the chest].
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ABSTRACT: To observe the hemodynamic changes and liver and kidney function variations in pregnant rats with pre-eclampsia after treatment with low-energy laser irradiation. Forty pregnant SD rats were randomly divided into the experimental group (group A), experimental control group (group B), blank control group (group C) and blank exposure group (group D) (n=10). The rats in groups A and B were injected with 1 µg/kg endotoxin via the tail vein at the 14th day of gestation, and those in groups C and D received normal saline injections. In groups A and B, low-energy laser irradiation of the chest was carried out since day 16 of gestation. Blood pressure, urine protein, liver and kidney function and the hemodynamic changes in the rats were observed. After the treatment, blood pressure, urine protein, ALT, BUN and Cr of group A were lower than those of group B (P<0.05), but similar with those in groups C and D (P>0.05). The blood and plasma viscosity and hematocrit of group A were also lower than those of group B (P<0.01), but comparable with those in groups C and D. Low-energy laser irradiation in the chest area may improve the hemodynamic indices, decrease blood pressure and urine protein, and ameliorate liver and kidney functions in pregnant rats with pre-eclampsia.Nan fang yi ke da xue xue bao = Journal of Southern Medical University 10/2010; 30(10):2259-62. -
Article: [Clinical outcomes of intracytoplasmic sperm injection (ICSI) and ISCI following fertilization failure in conventional IVF: a comparative analysis].
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ABSTRACT: To evaluate the clinical outcomes of intracytoplasmic sperm injection (ICSI) in patients with previous fertilization failure in conventional in vitro fertilization (IVF) procedures. Between January 2007 and December 2007, 27 ICSI cycles following a previous fertilization failure in conventional IVF (group A) and 57 direct ICSI cycles using ejaculated spermatozoa (group B) were performed, and the clinical outcomes of the two groups were analyzed. The fertilization rate per cycle of ICSI following a fertilization failure in conventional IVF was significantly higher than that of conventional IVF [(80.4-/+16.6)% vs (32.3-/+30.3)%, P<0.01]. The normal fertilization rate, high-quality embryo rate, clinical pregnancy rate per cycle in group A showed no significant differences from those in group B [(77.14-/+15.98)% vs (70.59-/+21.53)%, (28.68-/+23.86)% vs (27.18-/+23.97)%, and 48.1% vs 54.4%, respectively, P>0.05]. The cleavage rate and transferable embryos per cycle in group A were significantly higher than those in group B [(96.66-/+6.55)% vs (92.33-/+19.41)%, 2.67-/+0.56 vs 2.12-/+0.57, respectively, P<0.05]. ICSI after a previous fertilization failure of conventional IVF may significantly improve the fertilization rate and clinical outcomes of a second IVF-ET cycle.Nan fang yi ke da xue xue bao = Journal of Southern Medical University 05/2009; 29(5):993-5.
