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ABSTRACT: Biphasic hormone therapy at the stage of pre-gestation treatment of patients with habitual miscarriages stimulates the expression of progesterone receptors in the endometrium during the secretory phase of the menstrual cycle with full-value ultrastructural rearrangement of the endometrial glandular components in comparison with the patients receiving metabolic therapy alone.
Bulletin of Experimental Biology and Medicine 10/2009; 148(4):663-7. · 0.27 Impact Factor
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ABSTRACT: Structural reorganization of endotheliocytes was studied on models of various pathological processes: placental dysfunction, glomerular pathology, vibration syndrome, antiphospholipid syndrome, and diffuse angiokeratoma, all of these characterized by endothelial insufficiency. Universal modification of endothelial associations was revealed. It included a chain of stereotypical reactions: from degeneration alternating with compensatory hypertrophy to subsequent atrophy and death of endotheliocytes. The time course of the process was confirmed by the results of light microscopy in combination with ultrastructural examination and by evaluation of the biosynthetic reactions by in vitro radioautography.
Bulletin of Experimental Biology and Medicine 05/2009; 147(5):650-4. · 0.27 Impact Factor
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ABSTRACT: Ultrastructural, in vitro radioautographic, and stereological study of the morphogenesis of ovarian cystic formations in women of reproductive age distinguished ovariopathy as a common pathological phenomenon, developing as a result of the ovarian follicular cell regenerative and plastic insufficiency syndrome. Degenerative dystrophic changes in the follicular compartment, reduced biosynthetic reactions in the follicular cells, and reactive sclerosis of the stroma remodulate the parenchyma-stromal relationships.
Bulletin of Experimental Biology and Medicine 10/2007; 144(4):570-4. · 0.27 Impact Factor
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ABSTRACT: Normalization of the menstrual function in women with spontaneous abortion receiving sorbent and bioresonance (extremely high-frequency) therapy was evaluated by morphological criteria (correspondence of structural changes in the endometrium to the phase of the menstrual cycle). The absence of microvilli and cilia on the apical surface of surface and glandular epitheliocytes, presence of intranuclear tubules and giant mitochondria in the cytoplasm, and signs of apocrine secretion in epitheliocytes attested to the luteal phase of the cycle.
Bulletin of Experimental Biology and Medicine 12/2002; 134(5):505-8. · 0.27 Impact Factor