Abdolsamad Shikhzadeh

Zahedan University of Medical Sciences, Dowzdāb, Sīstān va Balūchestān, Iran

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Publications (10)10.18 Total impact

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    ABSTRACT: The purpose of this study was to determine the prevalence of musculoskeletal complaints and rheumatic diseases in southeast of Iran. Subjects were selected based on a cluster sampling from 20 districts of urban areas in Zahedan, Iran. Subjects 15 years old and over were randomly selected and interviewed by trained interviewers in their houses. The Community Oriented Program for the Control of Rheumatic Disease (COPCORD) and Core Questionnaire (CCQ) were used in this study. The people with musculoskeletal complaints (pain, stiffness and swelling) were examined by the rheumatologist. Laboratory tests and radiographic exams were carried out when necessary to further categorize diagnoses. Data were collected from October 10, 2008 to September 15, 2009. Two thousand and one hundred subjects including 921 (43.9%) males and 1179 (56.1%) females were interviewed. The average age of the population was 33.1 ± 14.7 years. The prevalence of complaints within the past 7 days prior to the interview was 54.13%. The most common sites of complaint were as follows: knee (30.59%), dorsolumbar (28.83%), shoulder (22.26%) and neck (17.07%). The most common rheumatic diseases were osteoarthritis and low back pain with the prevalence of 18.66% and 17.71%, respectively. Finally, the prevalence of rheumatoid arthritis was 0.98%. Musculoskeletal complaints are highly common in southeast Iran. Knee and low back pain were the most common sites of complaints. The most frequent diagnosed diseases were osteoarthritis of knee followed by low back pain and soft tissue rheumatism. Rheumatoid arthritis was the most prevalent inflammatory disease.
    International Journal of Rheumatic Diseases 10/2013; 16(5):509-17. · 1.65 Impact Factor
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    ABSTRACT: International Journal of Rheumatic Diseases
    International Journal of Rheumatic Diseases 01/2013; 16(2). · 1.65 Impact Factor
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    ABSTRACT: Background: The metabolic syndrome (MES) is associated with a high risk of diabetes and cardiovascular disease. The aim of the present study was to determine the prevalence of the metabolic syndrome as well as cut-off points for waist circumference (WC) for diagnosis of MES in Zahedan, southeast Iran. Methods: Totally, 1802 people (735 men and 1067 women) with metabolic syndrome were surveyed according to National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) and the International Diabetes Federation (IDF) criteria as well as obtained WC cut-off points for IDF criteria. Results: The prevalence of metabolic syndrome was higher in women than in men. In both sexes the prevalence increased with age. The prevalence of metabolic syndrome among 1802 individuals aged ≥19 years according to NCEP ATP III, IDF and IDF -AHA/NHLBI were 21.0% (15.4% in male, 24.9% female), 24.8 (20.0% in male, 28.1% in female) and 23.3% (19.7% in male, 25.8% in female), respectively. Low HDL-C (60.6%) and high WC (43.3%) were the most common components of the metabolic syndrome, followed by high triglycerides (32%), elevated glucose (17.1%) and high blood pressure (13%). Conclusion: Our data shows a high prevalence of MES in Zahedan, Southeast Iran, therefore, future health prevention strategies are required for the prevention of MES.
    Iranian journal of public health 02/2012; 41(2):70-76. · 0.24 Impact Factor
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    ABSTRACT: The metabolic syndrome (MES) is associated with a high risk of diabetes and cardiovascular disease. The aim of the present study was to determine the prevalence of the metabolic syndrome as well as cut-off points for waist circumference (WC) for diagnosis of MES in Zahedan, southeast Iran. Totally, 1802 people (735 men and 1067 women) with metabolic syndrome were surveyed according to National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) and the International Diabetes Federation (IDF) criteria as well as obtained WC cut-off points for IDF criteria. The prevalence of metabolic syndrome was higher in women than in men. In both sexes the prevalence increased with age. The prevalence of metabolic syndrome among 1802 individuals aged ≥19 years according to NCEP ATP III, IDF and IDF -AHA/NHLBI were 21.0% (15.4% in male, 24.9% female), 24.8 (20.0% in male, 28.1% in female) and 23.3% (19.7% in male, 25.8% in female), respectively. Low HDL-C (60.6%) and high WC (43.3%) were the most common components of the metabolic syndrome, followed by high triglycerides (32%), elevated glucose (17.1%) and high blood pressure (13%). Our data shows a high prevalence of MES in Zahedan, Southeast Iran, therefore, future health prevention strategies are required for the prevention of MES.
    Iranian Journal of Public Health 01/2012; 41(2):70-6. · 0.41 Impact Factor
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    ABSTRACT: There is conflicting data regarding leptin in gestational diabetes mellitus (GDM). The aim of the present study was to compare serum leptin levels between individuals with GDM and normal pregnancy. This case-control study was performed on 26 GDM and 22 healthy pregnant women. Leptin concentrations were measured using an enzyme immunoassay. The level of serum leptin was not significantly different between GDM (9.890 ± 7.764 ng/ml) and normal pregnant women (13.80 ± 10.32 ng/ml) (p = 0.14). There are no significant differences between GDM and normal pregnant women regarding leptin levels.
    Archives of Gynecology 09/2011; 284(3):539-42. · 0.91 Impact Factor
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    ABSTRACT: Several studies show a high prevalence of vitamin D deficiency in Asia. Data regarding the prevalence of vitamin D deficiency in southeast Iran are inadequate. The purpose of this study was to determine the prevalence of vitamin D deficiency in Zahedan, a sunny area in southeast Iran. This population-based cross-sectional study was performed on 993 apparently healthy subjects. Serum levels of 25-hydroxy vitamin D (25-OH vit D), parathyroid hormone, calcium, phosphate, and alkaline phosphatase activity were measured. Inadequate vitamin D status was diagnosed in 94.7% of the subjects (25-OH vit D <30 ng/ml). The frequencies of deficiency (<20 ng/ml), insufficiency (20-30 ng/ml), sufficiency (30-150 ng/ml), and toxicity (>150 ng/ml) were 85.2, 9.5, 5.3, and 0.0%, respectively. The results indicate that vitamin D deficiency is common in the population of Zahedan. Based on our results, fortification of milk and the use of supplements is suggested in this region.
    Annals of Nutrition and Metabolism 02/2011; 58(1):37-41. · 1.66 Impact Factor
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    ABSTRACT: Background: Burn injury is one of the major causes of morbidity and mortality worldwide. In addition to the financial burden it inflicts on the health care system, it can lead to psychologi-cal, social and physical distress both to the patient and family members. The aim of this study was to determine the epidemiological parameters in hospitalized burn patient. Methods: In a cross-sectional study we evaluated data of 1073 hospitalized burn patients in Zahedan Khatam Al Anbia hospital from 2005-2008. All data were extracted from medical record and analyze by SPSS software. A P-value less than 0.05 was considered significant. Results: Among 1073 patient with acute burn, 55.4% were male and 44.6% were female. The mean age was 20.94 year old and mean size of burn area was 49.11±29.65 total body surface area (TBSA). Total body surface area burned was significantly higher in those with self-burn (p=0.0001). In children younger than 15 year-old scalds (hot liquid) was the most frequent cause of burn (44%). There was a higher incidence of self-burning in women (p=0.0001) and the mean length of hospital stay was 6.32±5.27 days. The mortality rate in self-burn patient was 87.34 % and in total cases was 41.47 %. Conclusion: In the present study, most of the burns were noted in 16 to 20 years age group, and more in male than in female subjects. Burn was more frequent in children and adultness and they are considered high-risk groups with higher mortality and morbidity. This shows a need for comprehensive burn prevention programs.
    Shiraz E Medical Journal 01/2011; 12(1):11-21.
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    ABSTRACT: To our knowledge, there is no report regarding adenosine deaminase activity (ADA) in gestational diabetes mellitus (GDM). The aim of the present study was to investigate the level of serum ADA activity in normal pregnancy, GDM and normal non-pregnant women. The serum catalytic concentration of ADA was measured in samples of 20 GDM, 40 normal pregnant and 20 non-pregnant healthy women. Adenosine deaminase activity was significantly higher in GDM (24.30 +/- 8.04 IU/L) and pregnant women (23.88 +/- 8.66 IU/L) than those of normal non-pregnant individuals (11.85 +/- 3.23 IU/L) (P < 0.0001), but the ADA level was not significantly different from GDM and normal pregnant women (P = 0.97). Adenosine deaminase activity was significantly higher in GDM and pregnant individuals than normal group in this study. Previous reports in this field are contentious; therefore, ADA activity could be regulated in different population by immunologic and genetic factors.
    Archives of Gynecology 07/2009; 281(4):623-6. · 0.91 Impact Factor
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    ABSTRACT: Alpha-1-antitrpsin (AAT) is the main antiprotease of plasma. Concentration of serum alpha-1-antitrypsin (AAT) may not be delegate of the functional capacity of this antiprotease. To our knowledge there is not any report regarding the functional level of AAT in gestational diabetes mellitus (GDM). The aim of the present study was to determine serum trypsin inhibitory capacity (sTIC) in gestational diabetes mellitus. This case-control study was performed in 41 GDM and 40 healthy pregnant women. sTIC was measured by enzymatic assay. The serum trypsin inhibitory capacity was significantly lower (p<0.001) in GDM (5.84+/-2.27 micromol/min/ml) than healthy pregnant women (7.24+/-1.91 micromol/min/ml). In gestational diabetes mellitus reduction of serum trypsin inhibitory capacity may be due to non-enzymatic glycosylation of alpha-1-antitrypsin or oxidation of methionin in the active site of alpha-1-antitrypsin which remains to be cleared.
    Diabetes research and clinical practice 04/2009; 84(3):201-4. · 2.74 Impact Factor
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    ABSTRACT: Urinary system fistula to the hip joint is a rare complication. We report a case of delayed posterior urethral fistula to the hip joint following penetrating gunshot wound injury. A 37-year-old Iranian Balochi male was shot with a firearm in the superior part of his right pelvis. He underwent primary closure on the same day. Ten months later, he developed urinary retention. He underwent retrograde urethrography and antegrade cystography which showed a stricture measuring 5 cm in length. There was also a history of progressive pain in the right hip joint accompanied by low grade fever which started 2 months after the initial injury. Hip X-ray showed evidence of an acetabular cavity and femoral head destruction diagnostic of complicated septic arthritis. The patient subsequently underwent reconstructive surgery for the urethral stricture and urethral fistula via a transperineal approach followed by total hip arthroplasty. Hip joint contamination with urine following a urethro-acetabular fistula can lead to severe and disabling complications such as septic arthritis. We recommend that every clinician should keep these fistulas in mind as a complication of penetrating urethral injury and every attempt should be made for their early diagnosis and prompt treatment.
    Journal of Medical Case Reports 01/2009; 3:133.