Publications (9)31.07 Total impact
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Article: Keratomycosis complicating pterygium excision.
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ABSTRACT: The authors describe a case of keratomycosis that appeared after the exeresis of a pterygium. A 48-year-old patient had been referred with a red right eye associated with an abscess of the cornea along the ablation zone of the pterygium. The surgery had been performed a month beforehand. The abscess was 6 mm high and 4 mm wide. The authors instigated a treatment that included amphotericin B (0.25%) after noticing a clinical aspect evoking a fungal keratitis and finding several septate filaments on direct examination. On day 10, a Fusarium dimerum was isolated on Sabouraud agar. After 15 days of treatment, the result was favorable and the size of the ulceration as well as the size of the abscess had progressively decreased. The antifungal treatment was definitively stopped at 14 weeks. Infectious-related complications of the pterygium surgery are rare and are essentially caused by bacterial agents. Secondary infections by fungus are rare. There have been two previous cases reported: one that appeared 15 years after radiotherapy and another that appeared at 3 weeks post surgery, consecutive to the use of mitomycin C. To the authors' knowledge, this is the first case of a keratomycosis due to F. dimerum reported that complicated the exeresis of a pterygium without the use of an adjuvant antihealing treatment. Pterygium surgery is a common procedure; nevertheless, ophthalmologists need to be aware of the existence of potential infectious complications.Clinical Ophthalmology 01/2011; 5:1435-7. -
Article: Reemergence of syphilis in Martinique, 2001-2008.
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ABSTRACT: Syphilis reemerged in Martinique in 2004 and initially affected 3 HIV-infected patients. By March 2008, syphilis was diagnosed for 37 men and 18 women. As of October 31, 2009, this outbreak had not yet been brought under control. It initially affected mainly men who had sex with men before it spread to heterosexual persons, minority group members, and crack cocaine users.Emerging Infectious Diseases 01/2010; 16(1):106-9. · 6.79 Impact Factor -
Article: Reply to gómez-marín.
The Journal of Infectious Diseases 10/2009; 200(6):1012-3. · 6.41 Impact Factor -
Article: Genotype of 88 Toxoplasma gondii isolates associated with toxoplasmosis in immunocompromised patients and correlation with clinical findings.
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ABSTRACT: We report the genotyping analysis of Toxoplasma gondii isolates in samples collected from 88 immunocompromised patients, along with clinical and epidemiological data. Most of these samples were collected in France during the current decade by the Toxoplasma Biological Resource Center. Lack of specific anti-Toxoplasma treatment, pulmonary toxoplasmosis, and involvement of multiple organs were the 3 main risk factors associated with death for this patient group. Genotyping results with 6 microsatellite markers showed that type II isolates were predominant among patients who acquired toxoplasmic infection in Europe. Non-type II isolates included 13 different genotypes and were mainly collected from patients who acquired toxoplasmosis outside Europe. Type III was the second most common genotype recovered from patients, whereas type I was rare in our population. Three nonarchetypal genotypes were repeatedly recovered from different patients who acquired the infection in sub-Saharan Africa (genotypes Africa 1 and Africa 2) and in the French West Indies (genotype Caribbean 1). The distribution of genotypes (type II vs. non-type II) was not significantly different when patients were stratified by underlying cause of immunosuppression, site of infection, or outcome. We conclude that in immunocompromised patients, host factors are much more involved than parasite factors in patients' resistance or susceptibility to toxoplasmosis.The Journal of Infectious Diseases 05/2009; 199(8):1155-67. · 6.41 Impact Factor -
Article: Anicteric cholestasis among HIV infected patients with syphilis.
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ABSTRACT: In Martinique, among 9 HIV carriers recently diagnosed with early syphilis, 7 had biologic cholestasis. Less than half of the patients had been diagnosed on clinical grounds for syphilis (cutaneous eruption or syphilis in partner), whereas most of them were diagnosed on a systematic screening of HIV infected patients.Scandinavian Journal of Infectious Diseases 04/2009; 41(6-7):524-7. · 1.72 Impact Factor -
Article: Outbreak of keratomycosis attributable to Fusarium solani in the French West Indies.
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ABSTRACT: We report an unusual increase in the number of cases of keratomycosis attributable to Fusarium solani in contact lens wearers. Observational case series. Between November 2005 and May 2006, 14 corneal abscesses were reported at the University Hospital Center of Fort-de-France. Twelve patients were contact lens wearers, and 10 used Bausch & Lomb (Rochester, New York, USA) ReNu with MoistureLoc. Corneal scrapings were collected for microbiological analyses. In six months, five abscesses attributable to Fusarium solani in contact lens wearers, using Bausch & Lomb ReNu with MoistureLoc as contact lens solution, were reported. This study reports an epidemic of keratomycosis attributable to Fusarium solani among contact lens wearers in the Caribbean, during the same timeframe as a similar epidemic in Asia and North America. We are unaware of previous report of this phenomenon and could find no reference to it in a computerized search utilizing MEDLINE.American Journal of Ophthalmology 02/2007; 143(2):356-8. · 4.22 Impact Factor -
Article: [Evolution in the prevalence of intestinal parasitosis in the Fort de France University Hospital (Martinique)].
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ABSTRACT: Determine the prevalence of intestinal parasitosis between January 1, 1997 and December 31, 1999 in the microbiology laboratory of the Fort de France University Hospital. Retrospective study of the results of 4684 parasitological examinations of stools performed in 2704 patients between January 1, 1997 and December 31, 1999 in this laboratory. This survey showed the high prevalence of anguillulosis, found in 51.69% of infested patients and in 4.56% of the population studied, the ever high prevalence of non or scarcely pathogenic amoebas (Endolimax nanus, Dientamoeba fragilis, Entamoeba coli) found in 27.19% of infested patients and 1.88% of the population studied, together with that of hookworms (12.80% of infested patients and 1.13% of the population), and the persistence of lambliasis. This study also revealed the presence of cryptosporidies (7 cases) and microsporidies (4 cases) in the patients infected by the human immunodeficiency virus. These results confirm the trend of the past twenty Years and the results of surveys initiated by the national statistics board (INSERM) in 1978, 1988 and 1995-1995, with the regression of bilharziosis and the persistence of anguillulosis and hookworms. The improvement in living conditions and hygiene, the combined efforts of the health care workers and Authorities in Martinique over the past 30 Years in the fight against parasites have led to a great reduction in the prevalence of classical intestinal parasitosis. However, new parasites associated with HIV infection have appeared.La Presse Médicale 07/2004; 33(11):707-9. · 0.67 Impact Factor -
Article: Onychomycosis due to Exophiala jeanselmei.
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ABSTRACT: Exophiala jeanselmei is a dematiaceous fungus that may cause invasive diseases, particularly among immunocompromised hosts. Most reports mention cutaneous or subcutaneous lesions, but no case of nail involvement due to this fungus has been reported until now. A 60-year-old man presented with hyperkeratosis and black coloration of the nails of the two thumbs and the two big toes of 4 years' duration. He was a renal transplant recipient and had been treated with prednisone and azathioprine. E. jeanselmei was present on direct examination, then isolated in cultures on repeated samplings from all pathologic nails. He was cured after 6 months of treatment with itraconazole. We describe the first case of nail infection due to E. jeanselmei. Itraconazole, which provides a broad spectrum of action on fungal species and achieves high levels of active substance in many tissues, including the nails, appeared to be efficient upon such a nail localization of E. jeanselmei.Dermatology 02/2002; 204(2):150-2. · 2.05 Impact Factor -
Article: Letter to the Editors Malaria in the French West Indies
Tropical Medicine & International Health 12/2001; 5(3):227 - 228. · 2.80 Impact Factor
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2011
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Hospital Centre University of Fort de France
Fort-de-France, MQ, Martinique
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