Publications (3)14.16 Total impact
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Article: Electrocardiographic pattern combined with echocardiographic wall motion abnormalities in stress related cardiomyopathies: clinical and pathophysiological insights.
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ABSTRACT: We report five cases of stress related cardiomyopahies that occurred in post-menopausal women (age range from 49 to 90) consecutively admitted to our Department in the last year in different clinical settings: typical anginal pain, carotid endarterectomy, pulmonary edema, cardiogenic shock, and severe asthenia. Apical left ventricular involvement was observed in three patients in conjunction with ECG mild ST segment elevation in anterior precordial leads resembling acute anterior myocardial infarction; isolated mid ventricular dysfunction was present in two patients in conjunction with ST segment depression in the anterior precordial leads. The ECG evolved showing T wave inversion in four cases and normalized in one. In all cases, blood chemistry showed mild elevation of CK-MB and TN. The observed wall motion abnormalities were reversible in four of five cases during hospital stay. Stress echocardiography was performed in two patients (dobutamine in the patient with persistent mid-ventricular hypokinesis, exercise in another case) and correctly predicted the absence of coronary artery disease. We conclude that wall motion analysis at echocardiography combined with ECG ST segment changes and serum markers of myocardial necrosis (CK-MB and TN) may allow recognition of stress cardiomyopathies in different clinical settings. Echo stress may be proposed in those patients in whom some suspicion of coronary artery disease persists.Archivos de cardiología de México 01/2012; 82(1):22-30. -
Article: Kounis syndrome in a patient with ovarian cancer and allergy to iodinated contrast media: report of a case of vasospastic angina induced by chemotherapy.
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ABSTRACT: We report the case of a 71-year-old woman with previous coronary angioplasty, ovarian cancer with multiple metastases and allergy to iodinated contrast media, who developed vasospastic angina after several treatments with cisplatin and cyclophosphamide, so that we considered this as a case of "allergic angina" or Kounis syndrome (type II variant). The patient underwent standard anti-ischemic therapy with nitrates, calcium blocking agents and enoxaparin so having an uneventful outcome.International journal of cardiology 05/2009; 149(2):e62-5. · 7.08 Impact Factor -
Article: Tako-tsubo syndrome: report of a case with mild electrocardiographic changes but with multiple wall motion abnormalities.
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ABSTRACT: We report the case of a 60-year-old woman admitted to our hospital for typical chest pain with only mild ST segment depression in the anterior precordial leads but with left ventricular akinesia of the mid-infero-postero-lateral segments with sparing of the base and of the apical septum. Coronary angiography was normal and the patient was dismissed from our hospital after echocardiographic normalization in spite of persistent ECG repolarization changes. We conclude that echocardiographic examination allows recognition of atypical forms of "tako-tsubo" disease in presence of only subtle and non-specific repolarization changes.International journal of cardiology 03/2009; 144(2):244-8. · 7.08 Impact Factor
