Wenrui Zhang

Publications (3)5.94 Total impact

• Article: Quasi‐Aligned Ag–Nb2O5 Nanobelt Arrays with Enhanced Photocatalytic and Antibacterial Activities

  Biao Gao, Jijiang Fu, Kaifu Huo, Wenrui Zhang, Yonghong Xie, Paul K Chu
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  ABSTRACT: Quasi-aligned Nb2O5 nanobelt arrays 300–500 nm wide, 20–40 nm thick, and 5–10 μm long are fabricated directly on a Nb foil using a hydrothermal reaction in a KOH solution followed by protonation and calcination treatment. The morphology of the quasi-aligned nanobelts established during the hydrothermal growth of the KNb3O8 nanobelts is preserved after the ion exchange process which converts the products to H3ONb3O8, and Nb2O5 is produced eventually by calcination. The photocatalytic activity of the synthesized Nb2O5 nanobelts is evaluated for the first time. The Nb2O5 nanobelts are further functionalized using Ag nanoparticles to form heterostructured Ag–Nb2O5 nanobelts by immersion in a AgNO3 solution followed by UV (ultra-violet) light illumination. The heterostructured Ag–Nb2O5 nanobelts consisting of Nb2O5 nanobelts and Ag nanoparticles exhibit enhanced photocatalytic activity and can decompose dye pollutants more rapidly and efficiently because Ag nanoparticles on the Nb2O5 surface can serve as electron sinks which promote charge separation between the photogenerated electrons (e−) and holes (h+). In addition, the composite photocatalyst exhibits excellent antibacterial activities against both Escherichia coli (gram-negative) and Staphylococcus aureus (gram-positive) and is potentially useful in photodegradation of organic dye pollutants and antibacterial applications.
  Journal of the American Ceramic Society 03/2011; 94(8):2330 - 2338. · 2.27 Impact Factor
• Article: Soft X-ray radiation effects on yeast cells with energies on and off the O(K) absorption edge by a soft X-ray microprobe.

  Liang Chen, Jingwen Yan, Shiping Jiang, Wenrui Zhang
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  ABSTRACT: The cell killing abilities of soft X-rays on and off the oxygen K-shell edges on yeast cells have been investigated using a micrometer soft X-ray microprobe from synchrotron radiation. The dose depositions at different X-ray energies in the cell were discussed. At the same time, the cells were irradiated by (60)Co gamma-rays and the abilities in inducing yeast cell killing were compared with those produced by soft X-rays. The results showed that soft X-rays on and off the O(K) edge had higher ability of radiation damage than (60)Co gamma-rays. The total killing abilities of the three soft X-rays on yeast cells were almost similar and the differences of the X-rays in inducing yeast cell killing on and off the O(K) edge were not obvious.
  Radiation Protection Dosimetry 03/2009; 133(1):20-4. · 0.82 Impact Factor
• Source

  Available from: Qinghua Shi

  Article: Multiple origins of spontaneously arising micronuclei in HeLa cells: direct evidence from long-term live cell imaging.

  Xiaotang Rao, Yingyin Zhang, Qiyi Yi, Heli Hou, Bo Xu, Liang Chu, Yun Huang, Wenrui Zhang, Michael Fenech, Qinghua Shi
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  ABSTRACT: Although micronuclei (MNi) are extensively used to evaluate genotoxic effects and chromosome instability, the most basic issue regarding their origins has not been completely addressed due to limitations of traditional methods. Recently, long-term live cell imaging was developed to monitor the dynamics of single cell in a real-time and high-throughput manner. In the present study, this state-of-the-art technique was employed to examine spontaneous micronucleus (MN) formation in untreated HeLa cells. We demonstrate that spontaneous MNi are derived from incorrectly aligned chromosomes in metaphase (displaced chromosomes, DCs), lagging chromosomes (LCs) and broken chromosome bridges (CBs) in later mitotic stages, but not nuclear buds in S phase. However, most of bipolar mitoses with DCs (91.29%), LCs (73.11%) and broken CBs (88.93%) did not give rise to MNi. Our data also show directly, for the first time, that MNi could originate spontaneously from (1) MNi already presented in the mother cells; (2) nuclear fragments that appeared during mitosis with CB; and (3) chromosomes being extruded into a minicell which fused with one of the daughter cells later. Quantitatively, most of MNi originated from LCs (63.66%), DCs (10.97%) and broken CBs (9.25%). Taken together, these direct evidences show that there are multiple origins for spontaneously arising MNi in HeLa cells and each mechanism contributes to overall MN formation to different extents.
  Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 10/2008; 646(1-2):41-9. · 2.85 Impact Factor