ABSTRACT: We report a case of a 52-year-old man with multiple myeloma and rapidly progressive heart failure who died unexpectedly from a probable arrhythmia. Postmortem examination revealed infiltrative amyloid cardiomyopathy, a rare cause of predominantly diastolic myocardial disease. Cardiac amyloidosis should be considered in any patient presenting with congestive heart failure, preserved systolic function, and a discrepancy between a low QRS voltage on electrocardiography and an apparent left ventricular hypertrophy on sonogram. The pattern of left ventricular diastolic dysfunction changes during the course of amyloidosis and the classically described restrictive physiology occurs only in advanced stages of the disease.
Journal of Clinical Ultrasound 02/2009; 37(3):179-84. · 0.81 Impact Factor
New Jersey medicine: the journal of the Medical Society of New Jersey 11/2004; 101(10):29-34.
The American Journal of Geriatric Cardiology 14(5):269-70. · 1.04 Impact Factor