Luiza Napiórkowska

Publications of Luiza Napiórkowska

• Prevalence of low serum vitamin D concentration in an urban population of elderly women in Poland.

  Authors: Luiza Napiórkowska, Tadeusz Budlewski, Wioletta Jakubas-Kwiatkowska, Violeta Hamzy, Dariusz Gozdowski, Edward Franek

  Polskie archiwum medycyny wewnetrznej. 11/2009; 119(11):699-703.

  INTRODUCTION: So far only scarce data have been published regarding serum vitamin D concentrations in elderly women in Poland. OBJECTIVES: We aimed to assess prevalence of vitamin D deficiency in aINTRODUCTION: So far only scarce data have been published regarding serum vitamin D concentrations in elderly women in Poland. OBJECTIVES: We aimed to assess prevalence of vitamin D deficiency in a population of women aged 60 to 90 years and living in Warsaw. PATIENTS AND METHODS: The study comprised 274 women from the general population (mean age 69.1 -/+5.7 years, body mass index [BMI] 28.9 -/+4.6 kg/m2, serum creatinine concentration 0.7 -/+0.12 mg/dl). Subjects who had been treated with glucocorticoids or antifracture drugs, or supplemented with vitamin D or calcium, were excluded. The study was conducted in winter. Serum vitamin D, calcium, phosphate, and parathyroid hormone (PTH) concentrations were measured. RESULTS: The mean vitamin D concentration was 13.6 ng/ml in the whole examined population. Vitamin D levels above 30 ng/ml were detected in 4% of subjects. Vitamin D insufficiency (20-30 ng/ml) was found in 12.8% of subjects, and its deficiency (<20 ng/ml) in 83.2% of subjects. Vitamin D concentrations in women under and over 70 years of age did not differ significantly. There were no associations of vitamin D concentrations with age, BMI, renal function, or serum calcium concentrations. However, we observed a significant inverse correlation between vitamin D concentrations and PTH. CONCLUSIONS: The prevalence of low vitamin D concentrations in an urban population of elderly women in Poland is very high. Lower vitamin D levels are associated with a higher PTH concentration.

• [Senile osteoporosis.]

  Authors: Luiza Napiórkowska, Edward Franek

  Endokrynologia Polska. 02/2009; 60(2):110-114.

  The presented paper aims to summarize knowledge regarding senile osteoporosis. The article highlights high prevalence of the disease and the burden caused by osteoporotic fractures on the healthcareThe presented paper aims to summarize knowledge regarding senile osteoporosis. The article highlights high prevalence of the disease and the burden caused by osteoporotic fractures on the healthcare system. It describes shortly a complex ethiopathogenesis, in which vitamin D deficiency, other hormonal disturbances, protein-energy malnutrition, dysfunction of neuromuscular system and other factors may play a role. Possible diagnostics (x-rays, dual x-ray absorptiometry, 10-years fracture risk) and therapeutic methods are also presented.