Chris C Broomell

Publications of Chris C Broomell

• Janus-like Protein Cages. Spatially Controlled Dual-Functional Surface Modifications of Protein Cages.

  Authors: Sebyung Kang, Peter A Suci, Chris C Broomell, Kenji Iwahori, Mime Kobayashi, Ichiro Yamashita, Mark Young, Trevor Douglas

  Nano letters. 06/2009;

  Protein cages have been used both as size-constrained reaction vessels for nanomaterials synthesis and as nanoscale building blocks for higher order nanostructures. We generated Janus-like proteinProtein cages have been used both as size-constrained reaction vessels for nanomaterials synthesis and as nanoscale building blocks for higher order nanostructures. We generated Janus-like protein cages, which are dual functionalized with a fluorescent and an affinity label, and demonstrated control over both the stoichiometry and spatial distribution of the functional groups. The capability to toposelectively functionalize protein cages has allowed us to manipulate hierarchical assembly using the layer-by-layer assembly process. Janus-like protein cages expand the toolkit of nanoplatforms that can be used for directed assembly of nanostructured materials.

• Controlled assembly of bifunctional chimeric protein cages and composition analysis using noncovalent mass spectrometry.

  Authors: Sebyung Kang, Luke M Oltrogge, Chris C Broomell, Lars O Liepold, Peter E Prevelige, Mark Young, Trevor Douglas

  Journal of the American Chemical Society. 01/2009; 130(49):16527-9.