[show abstract][hide abstract] ABSTRACT: The methanolic extract of Trianthema portulacastrum (Aizoaceae) was evaluated for antihyperlipidemic and antioxidant activity in high-fat-diet–induced hyperlipidemic rats. It was found that the extract caused a significant reduction in the lipid levels in hyperlipidemic rats and was comparable with the standard anti-hyperlipidemic drug atorvastatin. It was also found that the plant extract increased the liver antioxidant enzyme (catalase, superoxide dismutase, glutathione) levels while reducing the lipid peroxide (malondialdehyde) levels.
Journal of Herbs Spices & Medicinal Plants 01/2010; 16:193-202.
[show abstract][hide abstract] ABSTRACT: The aim of the present study was to evaluate the anti hyperglycemic activity of methanolic extract of leaves of Salacia fruticosa (Family:Hippocrataceae) in alloxan induced diabetic rats. The hyperglycemic rats were divided into different groups and were treated with methanolic extract of S. fruticosa at a dose of 125 & 250mg/kg. Treatment with extract produced a significant dose dependent reduction in blood glucose levels and this anti hyperglycemic activity was comparable with the reference standard, metformin. The results of the present study revealed the anti-diabetic activity of methanolic extract of leaves of Salacia fruticosa in alloxan induced diabetic rats.
[show abstract][hide abstract] ABSTRACT: The present study was aimed at evaluating the anticonvulsant activity of some new isatin-5-sulphonamide derivativesagainst maximum electric shock induced and Pentylenetetrazol (PTZ) induced seizures in mice using phenytoin as astandard. All the five test compounds were effectiveagainst electric shock and PTZ induced convulsions at a dose of 100mg/kg. The anticonvulsant activities of test compounds were comparable with standard anticonvulsant , Phenytoin.