Daniel Antoniello

Montefiore Medical Center, New York City, NY, United States

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Publications (8)34.26 Total impact

  • Karen Jablonski, Daniel Antoniello
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    ABSTRACT: A 57-year-old right-handed man complained of difficulty using his hands post-coronary artery bypass graft (figure). Neurologic examination revealed signs of callosal disconnection without hemiparesis. When asked to perform limb gestures like "brush your teeth" or "wave goodbye," the right hand performed flawlessly whereas the left hand was severely apraxic (video on the Neurology® Web site at www.neurology.org).
    Neurology 05/2013; 80(22):e239. · 8.30 Impact Factor
  • Matthew S Robbins, Joe Verghese, Daniel Antoniello
    Clinical neurology and neurosurgery 05/2012; 114(6):823-5. · 1.30 Impact Factor
  • Matthew S Robbins, Joe Verghese, Daniel Antoniello
    Clinical neurology and neurosurgery 08/2011; 113(9):782-4. · 1.30 Impact Factor
  • Daniel Antoniello, Kenneth Heilman
    Cortex 03/2011; · 6.16 Impact Factor
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    ABSTRACT: Most improvement from poststroke aphasia occurs within the first 3 months, but there remains unexplained variability in recovery. Recently, we reported a strong correlation between initial impairment and change scores in motor recovery at 90 days. We wanted to determine whether aphasia recovery (defined as a change from baseline to 90 days) shows a comparably strong correlation and whether the relation was similar to that in motor recovery. Twenty-one stroke patients had aphasia scores on the Western Aphasia Battery (WAB) obtained on stroke admission (WAB(initial)) and at 90 days (WAB(3 mo)). The relation between actual change (Delta) scores (defined as WAB(3 mo)- WAB(initial)) and WAB(initial) was calculated in multiple-regression analysis. Regression analysis demonstrated that WAB(initial) was highly correlated with DeltaWAB (R(2)=0.81, P<0.001) and that, in addition, the relation between WAB(initial) and DeltaWAB was proportional, such that patients recovered 0.73 of maximal potential recovery (WAB(maximum)-WAB(initial)). We show that, like motor recovery, there is a highly predictable relation between aphasia recovery and initial impairment, which is also proportional in nature. The comparability of recovery from motor and language impairment suggests that common mechanisms may govern reduction of poststroke neurologic impairment across different functional domains and that they could be the focus of therapeutic intervention.
    Stroke 07/2010; 41(7):1485-8. · 6.16 Impact Factor
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    ABSTRACT: The presence of a phantom limb (PL) resulting from a cerebral lesion has been reported to be a rare event. No prior study, however, has systematically investigated the prevalence of this syndrome in a group of post-stroke individuals. Fifty post-stroke individuals were examined with structured interview/questionnaire to establish the presence and perceptual characteristics of PLs. We document the presence of phantom experiences in over half of these individuals (n=27). We provide details of these phantom experiences and further characterize these symptoms in terms of temporal qualities, posture, kinesthesia, and associated features. Twenty-two participants reported postural phantoms, which were perceived as illusions of limb position that commonly manifested while lying in bed at night - a time when visual input is removed from multi-sensory integration. Fourteen participants reported kinesthetic phantoms, with illusory movements ranging from simple single joint sensations to complex goal-directed phantom movements. A striking syndrome of near total volitional control of phantom movements was reported in four participants who had immobile plegic hands. Reduplicative phantom percepts were reported by only one participant. Similarly, phantom pain was present in only one individual - the sole participant with a pre-stroke limb amputation. The results suggest that stroke results in phantom experiences more commonly than previously described in the literature. We speculate that subtotal deafferance or defective motor efference after stroke may manifest intermittently as a PL.
    Cortex 10/2009; 46(9):1114-22. · 6.16 Impact Factor
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    Ronald M Lazar, Daniel Antoniello
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    ABSTRACT: Clinicians have long recognized the enormous variability of recovery among patients with aphasia. Accordingly, the identification of specific factors most important in determining the extent of recovery has been the subject of many investigations. Yet, the reasons for two patients of the same age, nearly identical clinical presentations, and similar MRI findings having completely dissimilar recoveries are still unknown. It remains difficult for a clinician to make a valid prognosis of language recovery in an individual patient. This article provides a review of aphasia-recovery research and a framework for approaching the variability of recovery in clinical practice.
    Current Neurology and Neuroscience Reports 12/2008; 8(6):497-502. · 3.78 Impact Factor
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    ABSTRACT: Patients with Parkinson disease (PD) have deficits in the neurotransmitter systems important for the normal allocation of attention. We sought to examine how the presence of PD influences the spatial allocation of reactive (bottom-up) and volitional (top-down) attention. To assess the spatial allocation of attention, we used the line bisection task. When assessing "bottom-up" attention, lateral blinking lights were or were not present during the time the PD and normal subjects were attempting to perform line bisections. In the top-down condition, these subjects were asked to name the color of the laterally presented light before bisecting lines. In the bottom-up condition, when compared with control subjects, the participants with PD were not abnormally distracted, but in the top-down condition, imperative stimuli on the right side of the line seemed to influence the PD subjects' allocation of attention. The results suggest that when voluntarily allocating attention rightward, PD patients have difficulty disengaging and/or reallocating their attention. This disengagement deficit might be related to the frontal-executive dysfunction associated with PD.
    Cognitive and behavioral neurology: official journal of the Society for Behavioral and Cognitive Neurology 10/2008; 21(3):138-42. · 1.09 Impact Factor

Publication Stats

68 Citations
34.26 Total Impact Points

Institutions

  • 2011–2013
    • Montefiore Medical Center
      • Albert Einstein College of Medicine
      New York City, NY, United States
  • 2009–2012
    • Albert Einstein College of Medicine
      • • Neurology, The Saul R. Korey Department of Neurology
      • • Department of Neuroradiology
      New York City, NY, United States
  • 2008
    • Columbia University
      New York City, New York, United States