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    ABSTRACT: To evaluate the application of autologous bone fresh-frozen and re-implantation in treatment of cranio-maxillofacial bone tumors. Four cases with cranio-maxillofacial bone tumors, including one in the frontal bone and three in the mandible, underwent osteoectomy, autologous diseased bone fresh-frozen by nitrogen, re-implantation of the bone and internal fixation by titanium plate to treat the bone tumor and reconstruct the bone defect. All four cases had one-stage healing 10-14 days after operation. One patient had pathological bone fracture 2 months postoperatively, the other three patients were well-cured without tumor recurrence and gained satisfied cosmetic appearance during 6 months to 3 years of follow-up. The X-ray films showed that the frozen bone was substituted by new bone formation. Autologous bone fresh-frozen and re-implantation is a feasible method in cranio-maxillofacial bone tumor treatment, especially for young patients. It make possible to do radical surgery and reconstruct the bone defect simultaneously, and is thus worthy of clinical application.
    Shanghai kou qiang yi xue = Shanghai journal of stomatology 11/2008; 17(5):545-7.