Deborah S Sarnoff

CUNY Graduate Center, New York City, New York, United States

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Publications (13)11.61 Total impact

  • Robert H Gotkin, Deborah S Sarnoff
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    ABSTRACT: Building upon the fractional CO<SUB>2</SUB> technology incorporated into the first generation SmartXide DOT (DEKA / ElEn, SpA, Calenzano, Italy) introduced in the U.S. in 2008, a second generation SmartXide Quadro has recently been introduced. This is a versatile device that has the ability to combine fractional CO<SUB>2</SUB> laser output for skin resurfacing with the synchronous delivery of bipolar radiofrequency (RF) energy for deeper, more diffuse heating. A pilot study was undertaken to demonstrate the safety and efficacy of the SmartXide Quadro, employing both fractional CO<SUB>2</SUB> laser output combined with the synchronous delivery of radiofrequency energy for the treatment of facial rhytides and acne scars. Ten patients, all women, six with facial rhytides and four with acne scarring, were treated with the SmartXide Quadro, a variably pulsed CO<SUB>2</SUB> laser with Pulse Shape Design® technology, a microablative DOT scanner and synchronized bipolar RF emission. Each patient was treated with a single fractional CO<SUB>2</SUB> laser-RF treatment; laser and RF parameters varied according to the severity of the rhytides or acne scars and were based upon both manufacturer-recommended settings and surgeon experience. Follow-up was at three days, one week, 2 weeks, and one month, three months, and six months after treatment. Results were judged by comparison of preoperative and post-operative photos evaluated by independent physicians, preoperative and post-operative grading by treating physicians, subjective evaluation of results by the patients themselves, and tabulation and categorization of adverse events (AEs). The SmartXide Quadro variably pulsed CO<SUB>2</SUB> laser with a microablative DOT scanner, with synchronous delivery of bipolar RF energy emission, proved to be both safe and effective in the treatment of facial rhytides and acne scars. The single treatment protocol was well tolerated and recovery was similar to fractional CO<SUB>2</SUB> laser skin resurfacing alone. The AEs were minimal and no significant complications occurred. J Drugs Dermatol. 2014;13(3):299-304.
    Journal of drugs in dermatology: JDD 03/2014; 13(3):299-304. · 1.16 Impact Factor
  • Deborah S Sarnoff, Robert H Gotkin
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    ABSTRACT: Full lips have always been associated with youth and beauty. Because of this, lip enhancement is one of the most frequently requested procedures in a cosmetic practice. For novice injectors, we recommend hyaluronic acid (HA) as the filler of choice. There is no skin test required; it is an easily obtainable, "off-the-shelf" product that is natural feeling when skillfully implanted in the soft tissues. Hyaluronic acid is easily reversible with hyaluronidase and, therefore, has an excellent safety profile. While Restylane® is the only FDA-approved HA filler with a specific indication for lip augmentation, one can use the following HA products off-label: Juvéderm® Ultra, Juvéderm Ultra Plus, Juvéderm Ultra XC, Juvéderm Ultra PLUS XC, Restylane-L®, Perlane®, Perlane-L®, and Belotero®. We present our six steps to achieve aesthetically pleasing augmented lips. While there is no single prescription for a "perfect" lip, nor a "one size fits all" approach for lip augmentation, these 6 steps can be used as a basic template for achieving a natural look. For more comprehensive, global perioral rejuvenation, our 6-step technique can be combined with the injection of neuromodulating agents and fractional laser skin resurfacing during the same treatment session.
    Journal of drugs in dermatology: JDD 09/2012; 11(9):1081-8. · 1.16 Impact Factor
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    ABSTRACT: Laser skin resurfacing has shifted over the past two decades from standard ablative resurfacing to non-ablative resurfacing and most recently, to fractional laser resurfacing. In this most recent category, fractional non-ablative lasers were first introduced followed by fractional ablative lasers, which offer an improved balance between safety and efficacy. In the current article, a review of fractional ablative resurfacing is presented alongside the results from a multi-center clinical study employing the fractional carbon dioxide (CO2) laser (SmartXide DOT, DEKA) for the treatment of rhytides, photoaging, scars and striae distensae.
    Journal of drugs in dermatology: JDD 04/2011; 10(4):352-62. · 1.16 Impact Factor
  • Ritu Saini, Stephanie Lehrhoff, Deborah S Sarnoff
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    ABSTRACT: The incidence of malignant melanoma has reached more than 62,000 people this past year alone. Much is unknown about the genetic predisposition of this cancer. The authors present a 62-year-old woman with a history of Charcot-Marie-Tooth disease (CMTD), diagnosed at age five, who has also developed multiple primary cutaneous malignant melanomas since 2003. The patient presented to the authors' clinic with a pigmented lesion on the left thigh, which was increasing in size and changing color. The patient was diagnosed with malignant melanoma in situ on biopsy. As both CMTD and malignant melanoma are neural crest derived disorders, this may suggest a shared underlying genetic defect. A gene locus of particular interest is 1p36, both previously recognized in the proposed pathogenesis of CMTD and malignant melanoma (MM).
    Journal of drugs in dermatology: JDD 02/2010; 9(2):164-6. · 1.16 Impact Factor
  • Ritu Saini, Deborah S Sarnoff
    Journal of drugs in dermatology: JDD 03/2009; 8(2):163-7. · 1.16 Impact Factor
  • Source
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    ABSTRACT: Carbon dioxide (CO2) laser skin resurfacing has been a mainstay of facial rejuvenation since its introduction in the mid 1990s. Recently, a new generation of fractional or microablative CO2 lasers has been introduced to the marketplace. According to the concept of fractional photothermolysis, these lasers ablate only a fraction of the epidermal and dermal architecture in the treatment area. An array of microscopic thermal wounds is created that ablates the epidermis and dermis within very tiny zones; adjacent to these areas, the epidermis and dermis are spared. This microablative process of laser skin resurfacing has proven safe and effective not only for facial rejuvenation, but elsewhere on the body as well. It is capable of improving wrinkles, acne scars, and other types of atrophic scars and benign pigmented lesions associated with elastotic, sun-damaged skin. Because of the areas of spared epidermis and dermis inherent in a procedure that employs fractional photothermolysis, healing is more rapid compared to fully ablative CO2 laser skin resurfacing and downtime is proportionately reduced. A series of 32 consecutive patients underwent a single laser resurfacing procedure with the a new microablative CO2 laser. All patients were followed for a minimum of 6 months and were asked to complete patient satisfaction questionnaires; a 6 month postoperative photographic evaluation by an independent physician, not involved in the treatment, was also performed. Both sets of data were graded and reported on a quartile scale. Results demonstrated greater than 50% improvement in almost all patients with those undergoing treatment for wrinkles, epidermal pigment or solar elastosis deriving the greatest change for the better (>75%).
    Journal of drugs in dermatology: JDD 02/2009; 8(2):138-44. · 1.16 Impact Factor
  • Journal of drugs in dermatology: JDD 09/2008; 7(8):764-6. · 1.16 Impact Factor
  • Deborah S Sarnoff, Ritu Saini
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    ABSTRACT: Epidermolytic hyperkeratosis is a rare genetic disorder of keratinization. In childhood, patients are erythrodermic and have a compromised stratum corneum, replaced with generalized hyperkeratosis as the patients age. Treatment consists of topical emollients as well as, topical and oral retinoids. Ultraviolet (UV) light, often in combination with psoralen ultraviolet A (PUVA) is widely used as a therapeutic modality for a multitude of hyperproliferative disorders. Although not strictly indicated for epidermolytic hyperkeratosis, it has been utilized as experimental treatment, particularly in the days prior to retinoids. Psoralen ultraviolet A has also been implicated in the development of nonmelanoma skin cancers, especially, squamous cell carcinoma (SCC). Retinoids are well-known to protect against nonmelanoma skin. A patient with epidermolytic hyperkeratosis with multiple nonmelanoma skin cancers, previously treated with PUVA and long-standing oral retinoids is reported.
    Journal of drugs in dermatology: JDD 05/2008; 7(5):475-8. · 1.16 Impact Factor
  • Ritu Saini, Deborah S Sarnoff
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    ABSTRACT: Basal cell carcinoma (BCC) is the most common human malignancy, which often occurs as a result of ultraviolet light on sun-exposed areas. A more rare location for the presentation of BCC is the non-sun-exposed genital area, where squamous cell cancer occurs frequently in the setting of human papilloma virus and chronic inflammatory lesions (i.e., lichen sclerosus et atrophicus). Consequently, such tumors may escape detection by the dermatologist and be mistaken by the gynecologist for an inflammatory condition. A delay in diagnosis can result in wider surgical margins and potential recurrences. We present a case of BCC of the vulva with involvement of the clitoris presenting with unilateral pruritus and treated as an allergic contact dermatitis with topical corticosteroids. The patient was treated with Mohs micrographic surgery in conjunction with topical imiquimod to spare surrounding tissue.
    Journal of drugs in dermatology: JDD 04/2008; 7(3):288-90. · 1.16 Impact Factor
  • Deborah S Sarnoff, Ritu Saini, Robert H Gotkin
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    ABSTRACT: The authors discuss various filling agents currently available that can be used to augment the lips, correct perioral rhytides, and enhance overall lip appearance. Fillers are compared and information provided about choosing the appropriate agent based on the needs of each patient to achieve the much coveted "pouty" look while avoiding hypercorrection. The authors posit that the goal for the upper lip is to create a form that harmonizes with the patient's unique features, taking into account age and ethnicity; the goal for the lower lip is to create bulk, greater prominence, and projection of the vermillion.
    Aesthetic surgery journal / the American Society for Aesthetic Plastic surgery 01/2008; 28(5):556-63.
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    ABSTRACT: Cellulite is an alteration of the topography of the skin that occurs in body areas where fat deposition seems to be under the influence of estrogen: mainly the hips, buttocks, thighs, and abdomen. The presence of cellulite is a significant source of patient dissatisfaction. There is currently no cure or consistently effective treatment for cellulite. The authors sought to show that the subdermal application of the neodymium-doped yttrium aluminium garnet (Nd:YAG) laser combined with autologous fat transplantation is a safe and effective treatment for cellulite. From January 2003 to December 2006, 52 female patients with Curri grade III to IV cellulite were treated with subdermal 1064-nm Nd:YAG laser lipolysis combined with autologous fat transplantation. Patient assessment was collected for data analysis. After the treatment, tissue samples were obtained in some subjects in order to ascertain the histologic effects of the laser treatment. This treatment resulted in significant clinical improvement in cellulite. The adverse effects were mild and temporary, and the postoperative period was well tolerated. A majority of patients (84.6%) rated the results of treatment as either good or excellent. The treatment of severe cases of cellulite (Curri grades III and IV) by a combination of 1064-nm Nd:YAG laser lipolysis and autologous fat transplantation proved to be both safe and effective. In addition, subdermal laser lipolysis has the advantage of inducing neocollagenesis and stimulating postoperative skin tightening. This represents a new treatment option for the ubiquitous cellulite disorder. Although this treatment has shown promising results in this pilot study, further studies are necessary in order to draw final conclusions.
    Aesthetic surgery journal / the American Society for Aesthetic Plastic surgery 01/2008; 28(6):656-62.
  • Journal of drugs in dermatology: JDD 01/2004; 3(2 Suppl):S3-16. · 1.16 Impact Factor
  • Deborah S Sarnoff, Robert H Gotkin
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    ABSTRACT: In the authors' experience, surgical repair of pitted scars, performed in conjunction with CO(2) laser resurfacing, produces no linear scars visible to the naked eye on the skin surface. Here, they describe their single-stage technique, suture-assisted resurfacing, in which, one-by-one, each ice-pick scar is incised with a triple bevel NoKor 18-gauge needle. (Aesthetic Surg J 2002;22:284-288.).
    Aesthetic surgery journal / the American Society for Aesthetic Plastic surgery 06/2002; 22(3):284-8.

Publication Stats

52 Citations
11.61 Total Impact Points


  • 2004–2010
    • CUNY Graduate Center
      New York City, New York, United States
  • 2009
    • Gracie Square Hospital, New York, NY
      New York City, New York, United States
  • 2008
    • Dechert LLP
      New York City, New York, United States