M Früh,
W Zhou,
R Zhai,
L Su,
R S Heist,
J C Wain, N S Nishioka,
T J Lynch,
F A Shepherd,
D C Christiani,
G Liu
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ABSTRACT: Helicobacter pylori (HP) infection appears protective against oesophageal adenocarcinoma (EA) risk. Matrix metalloproteinases (MMPs) are released in the presence of HP infection. In MMP2 wild-type individuals, HP was significantly protective of EA risk (adjusted odds ratio: 0.29; 95% confidence interval=0.1-0.7). Matrix metalloproteinases may modulate the EA-HP relationship.
British Journal of Cancer 03/2008; 98(4):689-92. · 5.04 Impact Factor
