P. Buisson

Université de Picardie Jules Verne, Amiens, Picardie, France

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Publications (18)8.08 Total impact

  • [Show abstract] [Hide abstract]
    ABSTRACT: The congenital mesoblastic nephroma (CMN) described by Bolande et al. in 1967 is a renal tumor often discovered in neonatal period and early childhood. It's usually considered as a benign tumor with good prognostic for which nephrectomy is the reference treatment. But some cases of local recidives and metastatic sites had been described in the literature. For these reasons histologic analysis and quality of follow up are very important. In this observation we describe a neonatal kind of CMN and we discuss this pathology.
    Progrès en Urologie 03/2012; 22(3):189-91. · 0.80 Impact Factor
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    ABSTRACT: The congenital mesoblastic nephroma (CMN) described by Bolande et al. in 1967 is a renal tumor often discovered in neonatal period and early childhood. It's usually considered as a benign tumor with good prognostic for which nephrectomy is the reference treatment. But some cases of local recidives and metastatic sites had been described in the literature. For these reasons histologic analysis and quality of follow up are very important. In this observation we describe a neonatal kind of CMN and we discuss this pathology.
    Progrès en Urologie. 03/2012; 22(3):189–191.
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    ABSTRACT: Cystinuria is an inherited autosomal-recessive disorder of renal reabsorption of the dibasic amino acids. It is the cause of about 6% of all kidney stones observed in children. Cystine is relatively insoluble at the physiological pH of urine. Cystine stones are characteristic and frequent recurrences are observed. We report on 4 cases and describe the initial presentation (obstructive renal failure, urinary sepsis, familial screening) and the medical and surgical management. Medical management is mainly based on hyperhydration and urine alkalinization. Long-term therapy with sulfhydryl agents to prevent formation of renal stones seems to be effective but adverse side effects are frequent, requiring the withdrawal of treatment. Urological management has evolved from surgical stone removal to minimally invasive procedures (extracorporeal shock wave lithotripsy, ureteroscopy).
    Archives de Pédiatrie 03/2011; · 0.36 Impact Factor
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    ABSTRACT: Objectifs La dilatation intestinale en amont d’une atrésie semble modifier la motricité. Un modèle animal de dilatation chronique a été créé afin d’étudier le segment iléal dilaté avant puis après remise en continuité (RC). Matériel et Méthodes Trois groupes de 7 rats ont été constitués : -témoins ;-fantômes (laparotomie à 4 et 6 semaines) ;-opérés (anse borgne iso-péristaltique iléale à 4 semaines, RC à 6). L’amplitude de contraction des lambeaux d’iléon a été étudiée in vitro en réponse à des stimulations électriques et pharmacologiques, l’épaisseur des couches musculaires déterminée par microscopie photonique. Résultats Les stimulations ont entraîné une contraction significative des lambeaux. Par rapport aux fantômes et témoins, l’amplitude des contractions de l’anse RC n’est pas significativement différente tandis que celle de l’anse dilatée l’est (p < 0,05). L’épaisseur des couches musculaires de l’anse dilatée est augmentée de 300% (p < 0,001) et de 250% après RC (p < 0,01). Discussion Notre étude montre des altérations de la motricité intestinale et une hyperplasie musculaire après obstruction prolongée avec possible récupération après RC. Ceci incite à poursuivre l’attitude classique soit une résection limitée.
    Archives de Pédiatrie 06/2010; 17(6):10-10. · 0.36 Impact Factor
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    ABSTRACT: A rat animal model of left colostomy was found to significantly impair the growth curve of rats. Assessment of the intestinal flora showed that colostomy mostly affects the cecal but not colonic microflora. Generally, the number of enterococci was increased in both ileum and cecum; cecal lactobacilli also rose, accounting for a promotion of lactic acid bacteria in colostomised rats. No significant differences between colostomised, laparotomised and control rats could be observed for the translocation of intestinal bacteria to internal organs of rats (i.e. spleen, kidneys, lungs or liver), whatever their diet. Heat-killed Lactobacillus acidophilus strain LB administration (dead probiotic bacteria) tended to exhibit a stimulatory effect on bifidobacteria, probably affecting the culture-medium fermentation substances included in the pharmaceutical product. This effect was abolished by laparotomy and colostomy. A trend towards a probiotic-like effect, not susceptible to colostomy, was also witnessed as counts of lactobacilli tended to increase in both cecum and colon of all animals fed with L. acidophilus LB.
    Folia Microbiologica 02/2008; 53(1):89-93. · 0.79 Impact Factor
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    ABSTRACT: Bladder tumour is rare in children and usually corresponds to embryonic rhabdomyosarcoma. However one of the differential diagnoses is inflammatory pseudotumour of the bladder which is a benign lesion with a good prognosis. The authors report the case of a 3-year-old boy who presented with macroscopic haematuria related to a lesion of the anterior bladder wall. Histological examination of the partial cystectomy specimen demonstrated inflammatory pseudotumour of the bladder that was confirmed by a review examination. Thirteen cases have been reported in the literature over the last ten years and all had a favourable outcome after complete resection of the lesion. Thorough histological examination of the lesion is therefore important to guide treatment.
    Progrès en Urologie 10/2007; 17(5):1005-7. · 0.80 Impact Factor
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    ABSTRACT: Introduction et but de l’étude La chirurgie digestive néonatale est souvent source de déséquilibre de l’écologie microbienne et d’atteinte du métabolisme intestinal pouvant devenir nocif, mais que l’on peut contrecarrer par les probiotiques. Le but de ce travail est d’évaluer l’impact du stress chirurgical sur la composition du mucus intestinal et l’activité de la phosphatase alcaline chez le jeune rat et l’effet bénéfique de L. acidophilus. Matériel et méthods Trente-six rats de race Wistar (100- 150 g) ont été inclus et répartis en 6 groupes : Gr Témoin (GT, n=6), n’a subi aucun traitement, Gr Fantôme, (GF, n=6), a subi une simple laparotomie, Gr Colostomisé, (GC, n=6); Gr témoin bis (GTbis, n=6), Gr Fantôme bis (GFbis, n=6)et Gr colostomisé bis (GCbis, n=6), ces 3 derniers groupes ont reçu une dose journalière de 10log9 L. acidophilus tués par la chaleur (Lactéol fort®). A J15, sacrifice des animaux et prélèvement de fragments d’intestins de 2 à 3 cm de l’iléon, du cæcum et du côlon pour le dosage des protéines, des sucres, des acides sialiques et pour l’étude de l’activité de la phosphatase alcaline. Résultats Ni le stress chirurgical ni l’admnistration de L. acidophilus n’influent sur le poids des animaux. La composition du mucus est modifiée par une expression faible des protéines, des sucres et des acides sialiques chez les animaux traités au probiotique et ceci quel que soit le fragment d’intestin (p<0.05 vs GT, GF, GC). L’activité de la phosphatase alcaline est perturbée suite à l’acte chirurgical, alors que le traitement par le L. Acidophilus la stimule remarquablement en particulier dans l’iléon (p<0.05 vs GT, GF, GC). Conclusions Nous observons un impact du stress chirurgical sur l’expression du mucus et de l’activité de la phosphatase alcaline ainsi que le rôle bénéfique du traitement par L. acidophilus sur l’homéostasie intestinale.
    Cahiers de Nutrition et de Diététique 01/2007; 21:77-77.
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    ABSTRACT: Bladder tumour is rare in children and usually corresponds to embryonic rhabdomyosarcoma. However, one of the differential diagnoses is inflammatory pseudotumour of the bladder, which is a benign lesion with a good prognosis. The authors report the case of a 3-year-old boy who presented with macroscopic haematuria related to a lesion of the anterior bladder wall. Histological examination of the partial cystectomy specimen demonstrated inflammatory pseudotumour of the bladder that was confirmed by a review examination. Thirteen cases have been reported in the literature over the last ten years and ail had a favourable outcome after complete resection of the lesion. Thorough histological examination of the lesion is therefore important to guide treatment.
    Progres En Urologie - PROG UROL. 01/2007; 17(5):1005-1007.
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    ABSTRACT: This study assessed the relative efficiency of different warming devices (surgical sheets covering the body and a tubegauze on the head, forced-air warming, warming mattress) commonly used to prevent body hypothermia during neonatal surgery. Dry heat losses were measured from a thermal manikin, which simulated a low-birth-weight neonate of 1,800 g. The manikin's surface temperatures (35.8 degrees C) corresponded to those of neonates nursed in closed incubators. Experiments were performed in a climatic chamber at an ambient temperature of 30 degrees C, as commonly found in operating theatres. The supine manikin was naked or covered with operative sheets with a 5x5 cm aperture over the abdomen. Its head could be covered by a tube-gauze. Additional warming was provided by conduction through a warming mattress (surface temperature, 39 degrees C) and/or by convection (Bair Hugger, forced-air temperature 38 degrees C). Covering the manikin with surgical sheets decreased the dry heat loss by 10.4 W. Additional forced-air warming was more efficient than the warming mattress to reduce the total dry heat loss (6.8 W vs 2.1 W). Heat losses were reduced by 7.9 W when combining the warming mattress and Bair Hugger. The heat loss from the head of the covered manikin was reduced from 4.5 W to 3.9 W when the head was covered with the tubegauze. Our data indicate that forced-air warming is more effective than conductive warming in preventing neonatal hypothermia during abdominal operations.
    Arbeitsphysiologie 10/2004; 92(6):694-7. · 2.66 Impact Factor
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    ABSTRACT: The Snodgrass urethroplasty, described in 1994 for the treatment of distal hypospadias, has very rapidly become a popular technique. However, incision of the urethral plate could be associated with a risk of stenosis of the neourethra. We present our preliminary results with this technique. Fifty two patients (47 distal forms and 5 midshaft forms) were operated according to this technique. Twenty five of these patients were reviewed with a follow-up of 18 months, and uroflowmetry was performed in 20 of them. Only the records of the other 27 patients were reviewed. The meatus is apical and oval and the glans is conical. There is no residual chordee. Early in our experience, we observed 13% of fistulas and 4% of stenoses. Four patients presented uroflowmetry results below the curve of the 5th percentile, but were completely asymptomatic. The results of this technique are excellent. With experience, our complication rate has been markedly decreased by performing deeper incision of the urethral plate. The risk of stenosis is theoretical rather than practical.
    Progrès en Urologie 07/2004; 14(3):385-9. · 0.80 Impact Factor
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    ABSTRACT: The body heat losses of premature neonates are difficult to assess since they are modified by the anthropomorphic characteristics of the infant. To solve this problem, thermal mannequins have been designed. The goal of the present study was to describe the biomedical uses of these models from two studies. The first one deals with the relationship between the thermal stress, the sleeping body positions and the sudden infant death syndrome, and the other with the assessment of heating devices used in neonatal surgery.A multisegment anthropomorphic thermal mannequin which represents a low-birth-weight neonate (body mass of 1,400 g) has been designed. In the first study, the mannequin was laid in prone or supine sleeping positions in a closed incubator, the air temperatures of which ranging from 25°C to 37°C. The results pointed out that the heat losses did not depend on the body positions. This discards the hypothesis that the supine sleeping position induces a thermal stress which can increase the mortality.In the second study, the mannequin was laid in a supine position in experimental conditions simulating an operative field. The thermal efficiency of a warming mattress associated (or not) with a convective warming device (Bair Hugger®) has been tested (air temperatures between 20°C and 30°C). The results showed that the Bair Hugger® was the most efficient device to rewarm the infant. When the Bair Hugger® (air temperature 38°C) is associated with the warming mattress (39°C), the air temperature of the surgery room can be reduced from 27°C to 20°C, to improve the thermal confort of the operators without strong disturbances of the thermal balance of the infant.
    Itbm-rbm. 01/2004; 25(4):219-226.
  • Journal of Pediatric Gastroenterology and Nutrition - J PEDIAT GASTROENTEROL NUTR. 01/2004; 39.
  • Archives de Pédiatrie 05/2003; 10. · 0.36 Impact Factor
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    ABSTRACT: The aim of this study was to evaluate the change in ureteropelvic junction management, from surgical correction to observation of the hydronephrosis. We checked wether or not it was deleterious for kidney. We retrospectively reviewed 96 charts between 1988 and 1998. Initial ultrasonography, and voiding cystourethrogram were available for all cases. Intravenous urography and diuretic renography were studied when available. Minimal follow-up of patients was one year. Patients were divided into three groups: surgery right away, surgery after observation, and observation only. Later was the diagnosis, more significant were the hydronephrosis and impairment of renal function (p < 0.01). In group operated on right away (69 cases), drainage improved, hydronephrosis decreased, but renal function did not improve significantly (p = 0.37). Sixteen patients were operated on after observation without deleterious effect for kidney. Eleven patients were only observed: hydronephrosis progressively decreased. Initial radiological results were not different between the last two groups (p > 0.05), and were not predictive of their course. Initial non operative management of hydronephrosis was not dangerous for renal function. It is advisable to detect at the earliest all signs of obstruction, because surgery improves renal drainage but not renal function.
    Archives de Pédiatrie 04/2003; 10(3):215-20. · 0.36 Impact Factor
  • Archives De Pediatrie - ARCHIVES PEDIATRIE. 01/2003; 10.
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    ABSTRACT: Purpose. – The aim of this study was to evaluate the change in ureteropelvic junction management, from surgical correction to observation of the hydronephrosis. We checked wether or not it was deleterious for kidney.Materials and methods. – We retrospectively reviewed 96 charts between 1988 and 1998. Initial ultrasonography, and voiding cystourethrogram were available for all cases. Intravenous urography and diuretic renography were studied when available. Minimal follow-up of patients was one year. Patients were divided into three groups: surgery right away, surgery after observation, and observation only.Results. – Later was the diagnosis, more significant were the hydronephrosis and impairment of renal function (p 0.01). In group operated on right away (69 cases), drainage improved, hydronephrosis decreased, but renal function did not improve significantly (p = 0.37). Sixteen patients were operated on after observation without deleterious effect for kidney. Eleven patients were only observed: hydronephrosis progressively decreased. Initial radiological results were not different between the last two groups (p > 0.05), and were not predictive of their course.Conclusion. – Initial non operative management of hydronephrosis was not dangerous for renal function. It is advisable to detect at the earliest all signs of obstruction, because surgery improves renal drainage but not renal function.
    Archives De Pediatrie - ARCHIVES PEDIATRIE. 01/2003; 10(3):215-220.
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    ABSTRACT: Transitional cell carcinoma of the kidney with caval tumour thrombus is extremely rare. The authors describe the radiological signs suggesting the preoperative diagnosis and guiding the therapeutic approach. They present the case of a 51-year-old patient with excluded caliceal stones, and review 17 cases published over a period of 24 years during which considerable progress has been made in radiological investigations. Only CT appears to be able to indicate this aetiology and allows retrograde ureteropyelography looking for a tumour of the urinary tract. MRI provides the best assessment of tumour involvement of the inferior vena cava. Nephroureterectomy with excision of a perimeatal bladder cuff and cavotomy is the only oncological surgical procedure, despite the extremely poor prognosis.
    Progrès en Urologie 05/2001; 11(2):288-92. · 0.80 Impact Factor
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    ABSTRACT: Le thrombus néoplasique de la veine cave inférieure associé à un carcinome transitionnel du rein est une entité exceptionnelle et de pronostic sombre. Une revue de la littérature a permis de retrouver 17 cas publiés. Nous rapportons ici un nouveau cas et discu-tons les difficultés du diagnostic préopératoire qui conditionne le geste chirurgical. CAS CLINIQUE M., 51 ans, d'origine portugaise, ayant comme antécé-dent une insuffisance coronarienne, présentait depuis 1987 des calculs radio-opaques asymptomatiques, cali-ciels supérieurs bilatéraux pour lesquels aucun traite-ment n'avait été réalisé. En janvier 1998, le patient était hospitalisé pour une hématurie macroscopique et des douleurs du flanc droit. L'UIV (Urographie Intra-Veineuse) montrait que les calculs du pôle supérieur du rein droit étaient dans une cavité calicielle devenue exclue (Figure 1), et d'autre part une désorganisation du groupe caliciel moyen et du bassinet droit. Les cal-culs situés au pôle supérieur du rein gauche avaient spontanément disparu. L'échographie rénale était considérée comme normale. En raison de l'apparition d'un angor instable ayant nécessité un double pontage coronarien, le patient était perdu de vue jusqu'en sep-tembre 1998 où il était de nouveau hospitalisé pour altération de l'état général et lombalgies bilatérales évoluant depuis 1 mois. Le bilan rhumatologique réali-sé, en particulier une tomodensitométrie vertébrale lombaire, était normale. Les examens biologiques met-taient en évidence une anémie inflammatoire avec un taux d'hémoglobine à 10.2g/dl, une CRP à 121, et sur-tout une insuffisance rénale rapidement évolutive asso-ciée à une oligoanurie. En effet, on notait une créatini-némie à 289 mmol/L à J1, 392 à J2, 606 à J3, 867 à J4 associée à une hyperkaliémie. Une échographie réali-sée en urgence le jour de son hospitalisation retrouvait une lithiase du pôle supérieur du rein droit, et surtout une tumeur de ce rein associée à un thrombus de la veine cave inférieure. La radiographie pulmonaire retrouvait une cardiomégalie, la trame pulmonaire était normale. Devant ce tableau rapidement évolutif, le patient nous était transféré. Une tomodensitométrie abdominale mettait en évidence un rein droit muet, glo-balement augmenté de volume, tumoral, sans déforma-tion de ses contours, un envahissement tumoral de la veine rénale droite et de la veine cave inférieure sus et sous rénale (Figure 2), l'extrémité distale du thrombus restant sous diaphragmatique. La veine rénale gauche était également envahie, expliquant l'évolution rapide Manuscrit reçu : septembre 2000, accepté : janvier 2001.