Kevin G McGuigan

Royal College of Surgeons in Ireland, Dublin, L, Ireland (Republic of Ireland)

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Publications (14)84.35 Total impact

  • Article: Solar water disinfection (SODIS): A review from bench-top to roof-top.
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    ABSTRACT: Solar water disinfection (SODIS) has been known for more than 30 years. The technique consists of placing water into transparent plastic or glass containers (normally 2L PET beverage bottles) which are then exposed to the sun. Exposure times vary from 6 to 48h depending on the intensity of sunlight and sensitivity of the pathogens. Its germicidal effect is based on the combined effect of thermal heating of solar light and UV radiation. It has been repeatedly shown to be effective for eliminating microbial pathogens and reduce diarrhoeal morbidity including cholera. Since 1980 much research has been carried out to investigate the mechanisms of solar radiation induced cell death in water and possible enhancement technologies to make it faster and safer. Since SODIS is simple to use and inexpensive, the method has spread throughout the developing world and is in daily use in more than 50 countries in Asia, Latin America, and Africa. More than 5 million people disinfect their drinking water with the solar disinfection (SODIS) technique. This review attempts to revise all relevant knowledge about solar disinfection from microbiological issues, laboratory research, solar testing, up to and including real application studies, limitations, factors influencing adoption of the technique and health impact.
    Journal of hazardous materials 08/2012; 235-236:29-46. · 4.14 Impact Factor
  • Article: Response to Comment on "A Randomized Intervention Study of Solar Disinfection of Drinking Water (SODIS) in the Prevention of Dysentery in Kenyan Children Aged under 5 Years".
    Martella du Preez, Ronan M Conroy, Kevin G McGuigan
    Environmental Science & Technology 03/2012; 46(5):3036-7. · 4.80 Impact Factor
  • Article: Response to comment on randomized intervention study of solar disinfection of drinking water in the prevention of dysentery in kenyan children aged under 5 years.
    Martella du Preez, Ronan M Conroy, Kevin G McGuigan
    Environmental Science & Technology 03/2012; 46(5):3033-4. · 4.80 Impact Factor
  • Article: Randomized intervention study of solar disinfection of drinking water in the prevention of dysentery in Kenyan children aged under 5 years.
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    ABSTRACT: We report the results of a randomized controlled intervention study (September 2007 to March 2009) investigating the effect of solar disinfection (SODIS) of drinking water on the incidence of dysentery, nondysentery diarrhea, and anthropometric measurements of height and weight among children of age 6 months to 5 years living in peri-urban and rural communities in Nakuru, Kenya. We compared 555 children in 404 households using SODIS with 534 children in 361 households with no intervention. Dysentery was recorded using a pictorial diary. Incidence rate ratios (IRR) for both number of days and episodes of dysentery and nondysentery diarrhea were significantly (P < 0.001) reduced by use of solar disinfection: dysentery days IRR = 0.56 (95% CI 0.40 to 0.79); dysentery episodes IRR = 0.55 (95% CI 0.42 to 0.73); nondysentery days IRR = 0.70 (95% CI 0.59 to 0.84); nondysentery episodes IRR = 0.73 (95% CI 0.63 to 0.84). Anthropometry measurements of weight and height showed median height-for-age was significantly increased in those on SODIS, corresponding to an average of 0.8 cm over a 1-year period over the group as a whole (95% CI 0.7 to 1.6 cm, P = 0.031). Median weight-for-age was higher in those on SODIS, corresponding to a 0.23 kg difference in weight over the same period; however, the confidence interval spanned zero and the effect fell short of statistical significance (95% CI -0.02 to 0.47 kg, P = 0.068). SODIS and control households did not differ in the microbial quality of their untreated household water over the follow-up period (P = 0.119), but E. coli concentrations in SODIS bottles were significantly lower than those in storage containers over all follow-up visits (P < 0.001). This is the first trial to show evidence of the effect of SODIS on childhood anthropometry, compared with children in the control group and should alleviate concerns expressed by some commentators that the lower rates of dysentery associated with SODIS are the product of biased reporting rather than reflective of genuinely decreased incidence.
    Environmental Science & Technology 09/2011; 45(21):9315-23. · 4.80 Impact Factor
  • Article: Randomized Intervention Study of Solar Disinfection of Drinking Water in the Prevention of Dysentery in Kenyan Children Aged under 5 Years
    Environmental Science and Technology 09/2011; · 5.23 Impact Factor
  • Article: High compliance randomized controlled field trial of solar disinfection of drinking water and its impact on childhood diarrhea in rural Cambodia.
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    ABSTRACT: Recent solar disinfection (SODIS) studies in Bolivia and South Africa have reported compliance rates below 35% resulting in no overall statistically significant benefit associated with disease rates. In this study, we report the results of a 1 year randomized controlled trial investigating the effect of SODIS of drinking water on the incidence of dysentery and nondysentery diarrhea among children of age 6 months to 5 years living in rural communities in Cambodia. We compared 426 children in 375 households using SODIS with 502 children in 407 households with no intervention. Study compliance was greater than 90% with only 5% of children having less than 10 months of follow-up and 2.3% having less than 6 months. Adjusted for water source type, children in the SODIS group had a reduced incidence of dysentery, with an incidence rate ratio (IRR) of 0.50 (95% CI 0.27-0.93, p = 0.029). SODIS also had a protective effect against nondysentery diarrhea, with an IRR of 0.37 (95% CI 0.29-0.48, p < 0.001). This study suggests strongly that SODIS is an effective and culturally acceptable point-of-use water treatment method in the culture of rural Cambodia and may be of benefit among similar communities in neighboring South East Asian countries.
    Environmental Science & Technology 08/2011; 45(18):7862-7. · 4.80 Impact Factor
  • Article: A preliminary Ames fluctuation assay assessment of the genotoxicity of drinking water that has been solar disinfected in polyethylene terephthalate (PET) bottles.
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    ABSTRACT: Though microbially safe, concerns have been raised about the genotoxic/mutagenic quality of solar-disinfected drinking water, which might be compromised as a result of photodegradation of polyethylene terephthalate (PET) bottles used as SODIS reactors. This study assessed genotoxic risk associated with the possible release of genotoxic compounds into water from PET bottles during SODIS, using the Ames fluctuation test. Negative genotoxicity results were obtained for water samples that had been in PET bottles and exposed to normal SODIS conditions (strong natural sunlight) over 6 months. Under SODIS conditions, bottles were exposed to 6 h of sunlight, followed by overnight room temperature storage. They were then emptied and refilled the following day and exposed to sunlight again. Genotoxicity was detected after 2 months in water stored in PET bottles and exposed continuously (without refilling) to sunlight for a period ranging from 1 to 6 months. However, similar genotoxicity results were also observed for the dark control (without refill) samples at the same time-point and in no other samples after that time; therefore it is unlikely that this genotoxicity event is related to solar exposure.
    Journal of Water and Health 12/2010; 8(4):712-9. · 1.37 Impact Factor
  • Article: Solar disinfection of drinking water in the prevention of dysentery in South African children aged under 5 years: the role of participant motivation.
    Martella Du Preez, Kevin G Mcguigan, Ronan M Conroy
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    ABSTRACT: Solar disinfection (SODIS) effectively improves the microbial quality of drinking water for preventing diarrhea; however, the effect of participant motivation has not been studied. This 1-year randomized controlled trial investigated the effect of SODIS of drinking water and motivation on the incidence of dysentery and nondysentery diarrhea among children of age 6 months to 5 years living in periurban communities in South Africa.We compared 383 children in 297 households using SODIS with 335 children in 267 households with no intervention. At baseline 62.4% of the study households had stored water which met World Health Organization guidelines for zero thermotolerant coliforms per 100 mL. Dysentery was recorded using a pictorial diary. Incidence of dysentery was significantly associated with higher motivation, defined as 75% or better completion of diarrhea data. Incidence rates were lower in those drinking solar disinfected water (incidence rate ratio 0.64, 95% CI 0.39 - 1.0, P = 0.071) but not statistically significant. Compared with the control, participants with higher motivation achieved a significant reduction in dysentery (incidence rate ratio 0.36, 95% CI 0.16 - 0.81, P = 0.014). However, there was no significant reduction in risk at lower levels of motivation. Solar disinfection was not significantly associated with nondysentery diarrhea risk overall (P = 0.419). A statistically significant reduction in dysentery was achieved only in households with higher motivation, showing that motivation is a significant determinant for measurable health gains. Failure of three-quarters of participants to achieve a significant reduction in dysentery suggests that research into effective implementation is required.
    Environmental Science & Technology 10/2010; 44(22):8744-9. · 4.80 Impact Factor
  • Article: Investigating the microbial inactivation efficiency of a 25 L batch solar disinfection (SODIS) reactor enhanced with a compound parabolic collector (CPC) for household use
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    ABSTRACT: BACKGROUND: A simple point-of-use solar disinfection (SODIS) reactor was designed to treat 25 L of water and was constructed from a methacrylate tube placed along the linear focus of a compound parabolic concentrator (CPC) and mounted at 37° inclination. Experiments were carried out over a 7 month period by seeding a 106 CFU mL−1 concentration of Escherichia coli K-12 in 25 L of well water or turbid water to mimic field conditions and determine the microbial effectiveness of the reactor.RESULTS: During periods of strong sunlight, complete inactivation of bacteria occurred in under 6 h, even with water temperatures < 40 °C. Under cloudy and low solar intensity conditions, prolonged exposure was needed. Turbid water (100 NTU) was disinfected in 7 h with water temperatures > 50 °C. No regrowth of bacteria occurred within 24 h and 48 h following solar disinfection. The construction cost of this prototype reactor was approximately US$ 200 but with an expected lifetime of 10 years, the running cost of the reactor is expected to be US$ 0.002 L−1.CONCLUSION: This study confirms that significant water disinfection can be achieved using a low cost CPC-enhanced 25 L batch SODIS reactor. Copyright © 2010 Society of Chemical Industry
    Journal of Chemical Technology & Biotechnology 07/2010; 85(8):1028 - 1037. · 2.17 Impact Factor
  • Article: Effect of the radiation intensity, water turbidity and exposure time on the survival of Cryptosporidium during simulated solar disinfection of drinking water.
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    ABSTRACT: The solar disinfection (SODIS) technique is a highly effective process that makes use of solar energy to inactivate pathogenic microorganisms in drinking water in developing countries. The pathogenic protozoan parasite Cryptosporidium parvum is often found in surface waters and is associated with waterborne outbreaks of cryptosporidiosis. In the present study, a complete multi-factorial mathematical model was used to investigate the combined effects of the intensity of solar radiation (200, 600 and 900W/m(2) in the 320nm to 10microm range), water turbidity (5, 100 and 300 NTU) and exposure time (4, 8 and 12h) on the viability and infectivity of C. parvum oocysts during simulated SODIS procedures at a constant temperature of 30 degrees C. All three factors had significant effects (p<0.05) on C. parvum survival, as did the interactions of water turbidity with radiation intensity and radiation intensity with exposure time. However, the parameter with the greatest effect was the intensity of radiation; levels > or =600W/m(2) and times of exposure between 8 and 12h were required to reduce the oocyst infectivity in water samples with different degrees of turbidity.
    Acta tropica 06/2009; 112(1):43-8. · 2.22 Impact Factor
  • Article: Solar disinfection of drinking water (SODIS): an investigation of the effect of UV-A dose on inactivation efficiency.
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    ABSTRACT: The effect of solar UV-A irradiance and solar UV-A dose on the inactivation of Escherichia coli K-12 using solar disinfection (SODIS) was studied. E. coli K-12 was seeded in natural well-water contained in borosilicate glass tubes and exposed to sunlight at different irradiances and doses of solar UV radiation. In addition, E. coli K-12 was also inoculated into poly(ethylene) terephthalate (PET) bottles and in a continuous flow system (10 L min(-1)) to determine the effect of an interrupted and uninterrupted solar dose on inactivation. Results showed that inactivation from approximately 10(6) CFU mL(-1) to below the detection level (4 CFU/mL) for E. coli K-12, is a function of the total uninterrupted dose delivered to the bacteria and that the minimum dose should be >108 kJ m(-2) for the conditions described (spectral range of 0.295-0.385 microm). For complete inactivation to below the limit of detection, this dose needs to be received regardless of the incident solar UV intensity and needs to be delivered in a continuous and uninterrupted manner. This is illustrated by a continuous flow system in which bacteria were not fully inactivated (residual viable concentration approximately 10(2) CFU/mL) even after 5 h of exposure to strong sunlight and a cumulative dose of >108 kJ m(-2). This has serious implications for attempts to scale-up solar disinfection through the use of re-circulatory continuous flow reactors.
    Photochemical and Photobiological Sciences 05/2009; 8(5):587-95. · 2.58 Impact Factor
  • Article: Investigation of a glottal related harmonics-to-noise ratio and spectral tilt as indicators of glottal noise in synthesized and human voice signals.
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    ABSTRACT: The harmonics-to-noise ratio (HNR) of the voiced speech signal has implicitly been used to infer information regarding the turbulent noise level at the glottis. However, two problems exist for inferring glottal noise attributes from the HNR of the speech wave form: (i) the measure is fundamental frequency (f0) dependent for equal levels of glottal noise, and (ii) any deviation from signal periodicity affects the ratio, not just turbulent noise. An alternative harmonics-to-noise ratio formulation [glottal related HNR (GHNR')] is proposed to overcome the former problem. In GHNR' a mean over the spectral range of interest of the HNRs at specific harmonic/between-harmonic frequencies (expressed in linear scale) is calculated. For the latter issue [(ii)] two spectral tilt measures are shown, using synthesis data, to be sensitive to glottal noise while at the same time being comparatively insensitive to other glottal aperiodicities. The theoretical development predicts that the spectral tilt measures reduce as noise levels increase. A conventional HNR estimator, GHNR' and two spectral tilt measures are applied to a data set of 13 pathological and 12 normal voice samples. One of the tilt measures and GHNR' are shown to provide statistically significant differentiating power over a conventional HNR estimator.
    The Journal of the Acoustical Society of America 04/2008; 123(3):1642-52. · 1.55 Impact Factor
  • Article: Disinfection of drinking water contaminated with Cryptosporidium parvum oocysts under natural sunlight and using the photocatalyst TiO2.
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    ABSTRACT: The results of a batch-process solar disinfection (SODIS) and solar photocatalytic disinfection (SPCDIS) on drinking water contaminated with Cryptosporidium are reported. Cryptosporidium parvum oocyst suspensions were exposed to natural sunlight in Southern Spain and the oocyst viability was evaluated using two vital dyes [4',6-diamidino-2-phenylindole (DAPI) and propidium iodide (PI)]. SODIS exposures (strong sunlight) of 8 and 12h reduced oocyst viability from 98% (+/-1.3%) to 11.7% (+/-0.9%) and 0.3% (+/-0.33%), respectively. SODIS reactors fitted with flexible plastic inserts coated with TiO2 powder (SPCDIS) were found to be more effective than those which were not. After 8 and 16 h of overcast and cloudy solar irradiance conditions, SPCDIS reduced oocyst viability from 98.3% (+/-0.3%) to 37.7% (+/-2.6%) and 11.7% (+/-0.7%), respectively, versus to that achieved using SODIS of 81.3% (+/-1.6%) and 36.0% (+/-1.0%), respectively. These results confirm that solar disinfection of drinking water can be an effective household intervention against Cryptosporidium contamination.
    Journal of Photochemistry and Photobiology B Biology 10/2007; 88(2-3):105-11. · 2.81 Impact Factor
  • Article: Cooking the waste.
    Kevin G McGuigan, Siobhán C Kehoe
    The Lancet 11/2003; 362(9392):1251-2. · 38.28 Impact Factor