Sang-Kyu Park

Publications (3)3.75 Total impact

• Source

  Available from: PubMed Central

  Article: Acute Physiology and Chronic Health Evaluation II and Simplified Acute Physiology Score II in predicting hospital mortality of neurosurgical intensive care unit patients.

  Sang-Kyu Park, Hyoung-Joon Chun, Dong-Won Kim, Tai-Ho Im, Hyun-Jong Hong, Hyeong-Joong Yi
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  ABSTRACT: We study the predictive power of Acute Physiology and Chronic Health Evaluation II (APACHE II) and Simplified Acute Physiology Score II (SAPS II) in neurosurgical intensive care unit (ICU) patients. Retrospective investigation was conducted on 672 consecutive ICU patients during the last 2 yr. Data were collected during the first 24 hours of admission and analyzed to calculate predicted mortality. Mortality predicted by two systems was compared and, multivariate analyses were then performed for subarachnoid hemorrhage (SAH) and traumatic brain injury (TBI) patients. Observed mortality was 24.8% whereas predicted mortalities were 37.7% and 38.4%, according to APACHE II and SAPS II. Calibration curve was close to the line of perfect prediction. SAPS II was not statistically significant according to a Lemeshow-Hosmer test, but slightly favored by area under the curve (AUC). In SAH patients, SAPS II was an independent predictor for mortality. In TBI patients, both systems had independent prognostic implications. Scoring systems are useful in predicting mortality and measuring performance in neurosurgical ICU setting. TBI patients are more affected by systemic insults than SAH patients, and this discrepancy of predicting mortality in each neurosurgical disease prompts us to develop a more specific scoring system targeted to cerebral dysfunction.
  Journal of Korean medical science 07/2009; 24(3):420-6. · 0.84 Impact Factor
• Article: Aneurysmal subarachnoid hemorrhage in young adults: a gender comparison study.

  Sang Kyu Park, Jae Min Kim, Jae Hoon Kim, Jin Hwan Cheong, Koang Hum Bak, Choong Hyun Kim
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  ABSTRACT: Aneurysmal subarachnoid hemorrhage is uncommon in young adults. The aim of this study was to compare clinical characteristics of ruptured aneurysms between males and females in the third or fourth decade of life. We retrospectively investigated 301 patients who underwent surgery for ruptured cerebral aneurysms over 6 years. Among them, 53 patients were aged between 20-39 years. Clinical characteristics and related variables were compared between genders. In general, there was a favorable outcome in either gender (84.9%). There was a higher incidence of multiplicity and intraoperative rupture in females, as well as a significant difference in aneurysm location between genders (p=0.030, p=0.014, and p=0.027 respectively). Overall outcome was not different between the two groups. These results suggest that aneurysm formation may differ between genders.
  Journal of Clinical Neuroscience 05/2008; 15(4):389-92. · 1.25 Impact Factor
• Article: Metastasizing malignant peripheral nerve sheath tumor initially presenting as intracerebral hemorrhage. Case report and review of the literature.

  Sang-Kyu Park, Hyeong-Joong Yi, Seung-Sam Paik, Young-Jin Kim, Yong Ko, Suck-Jun Oh
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  ABSTRACT: Malignant peripheral nerve sheath tumors, infrequent sarcomas arising within a peripheral nerve, mostly metastasize to the lung at terminal stage of disease. However, metastasis to the brain without pulmonary involvement is quite unlikely to occur. A 21-year-old man was brought in the emergency department due to sudden unconsciousness, and imaging studies showed huge intracerebral hemorrhage. Surgical removal and adjuvant therapy was performed for pathologically proven MPNST. Concurrent painful chest masses were also confirmed as MPNST through surgical resection. Nine months after craniotomy, multiple masses in the lung field and axilla region were uncovered, and surgical resection followed. Despite postoperative irradiation, the patient died of the respiratory complications at 16 months after craniotomy. To our knowledge, this kind of metastatic cerebral bleeding is the first case that was ever reported. The MPNST actually can exhibit an apoplectic manifestation even without pulmonary involvement in a young adult, albeit this is quite rare. Thus, high index of suspicion should be paid to minute complaints regarding MPNST in peripheral locations so as not to overlook an advanced or metastasized disease.
  Surgical Neurology 08/2007; 68(1):79-84; discussion 84. · 1.67 Impact Factor