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ABSTRACT: To evaluate the clinical results of tube gastrostomy in radical cystectomy and ileal conduit.
We retrospectively analyzed the data of 98 patients undergoing radical cystectomy and ileal conduit between March 2007 and February 2010. According to postoperative gastrointestinal decompression methods, the patients were divided into nasogastric decompression group (n=50) and tube gastrostomy group (n=48), and the gastrointestinal recovery time, surgical complications and hospital stay were compared between them.
No statistical difference was found in gastrointestinal recovery time, hospital stay, or surgical complications between the two groups, but the incidence of pulmonary infection was significantly lower in tube gastrostomy group than in nasogastric decompression group (P<0.05).
Tube gastrostomy is an easy, safe and effective means for gastric decompression after radical cystectomy with ileal conduit, especially suitable for elderly patients and those with potential pulmonary disorder.
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 08/2012; 32(8):1194-6.
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ABSTRACT: Primary testicular non-Hodgkin's lymphoma (TNHL) was first described as a clinical entity in 1866. It is a rare disease which accounts for 1% of all non-Hodgkin's lymphoma, 2% of all extranodal lymphomas and 5% of all testicular neoplasms. Hemophagocytic syndrome (HPS) is a rare but distinct condition caused by inappropriate and dysregulated activation of the immune system. We report a 47-year-old man with primary TNHL who developed HPS four months after occurrence of scrotal swelling. To the best of our knowledge, primary TNHL associated with HPS has not previously been reported.
Oncology letters 07/2012; 4(1):59-62. · 0.11 Impact Factor
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ABSTRACT: The X-ray repair cross-complementing group 3 (XRCC3), one of the DNA repair genes, was suggested to play an imperative role in the development of carcinogenesis. The objective of this study was to evaluate the role of the XRCC3 T241M polymorphism in bladder cancer susceptibility in a Chinese population. We genotyped 150 bladder cancer cases and 150 healthy controls who had been frequency matched to cases by age and sex. Genotypes were determined by polymerase chain reaction-restriction fragment length polymorphism analysis. A significant association was found between smoker and bladder cancer [odds ratio (OR)=1.97, 95% confidence interval (CI)=1.24-3.13, p=0.004]. The XRCC3 241MM genotype was more frequent in the bladder cancer group than in the healthy controls group (OR=3.22, 95% CI=1.14-9.11, p=0.03). There were no significant associations between any genotypes and the stage, grade, and histological type of bladder cancer. Our study suggested an increased risk role of XRCC3 241MM genotype in bladder cancer susceptibility in a Chinese population.
Genetic Testing and Molecular Biomarkers 02/2012; 16(6):640-3. · 1.11 Impact Factor
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ABSTRACT: To determine the relationship between comorbidity and outcome after radical cystectomy in Chinese patients by using the Adult Comorbidity Evaluation (ACE)-27 index. Two-hundred-and-forty-six patients treated with radical cystectomy at the Second Xiangya Hospital of Central South University, Hunan Province, China between 2000 and 2010 were retrospectively analyzed. Medical records were reviewed for age, gender, delayed time of radical cystectomy, urinary diversion type, pelvic lymphadenectomy status, TNM stage, and pathological grade. Comorbidity information was assessed by the ACE-27 index. The outcome measurement was overall survival. Univariate and multivariate Cox proportional hazards regression analyses were used to determine the association between comorbidity and outcome. The study population consisted of 215 (87.40%) males and 31 (12.60%) females with a mean age of 62±11 years. Median duration of follow-up was 47±31 months. A total of 151 (61.38%) patents died during follow-up. Of those, 118 (47.97%) had at least one comorbidity. According to the ACE-27 scores, 128 (52.03%) patients had no comorbidity, 79 (32.11%) had mild, 33 (13.41%) had moderate, and 6 (2.45%) had severe comorbidities. Multivariate analysis indicated that moderate (p=0.002) and severe (p<0.001) comorbidity was significantly associated with decreased overall survival. In addition, age ≥70 years (p=0.002), delayed time of radical cystectomy >12 weeks (p=0.044), pelvic lymphadenectomy status (p=0.014), and TNM stage >T3 (p<0.001) were determined to be independent risk factors of overall survival. Increasing severity of comorbidity statistically correlated with decreased overall survival after radical cystectomy.
Asian Pacific journal of cancer prevention: APJCP 01/2012; 13(3):827-31. · 0.66 Impact Factor
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ABSTRACT: Leiomyosarcoma is a rarely seen neoplasm of the ureter, with less than 20 cases being reported in the literature to date. It is important to distinguish leiomyosarcoma from rhabdomyosarcoma, with the aid of immunohistochemical markers. We report the clinical features, histology, imaging and treatment of ureteral leiomyosarcoma in a female patient.
Asian Journal of Surgery 11/2008; 31(4):191-4. · 0.57 Impact Factor
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ABSTRACT: Penile amputation and successful replantation is very uncommon, and routine standardized procedures for dealing with this medical condition do not exist. A case of a penile amputation and successful replantation is presented. This report presents the microsurgical procedure and postoperative care that led to successful engraftment and function. Of particular interest was the use of hyperbaric oxygen to accelerate the healing process. A review of the published data and future methods of increasing success of such surgical procedures is provided.
Urology 06/2007; 69(5):983.e3-5. · 2.43 Impact Factor
