-
[show abstract]
[hide abstract]
ABSTRACT: Background and Objective: There is a controversy regarding universal versus targeted screening for hypothyroidism during pregnancy. We studied the prevalence and the associated risk factors of hypothyroidism. The secondary objective of the study was to compare the maternal and perinatal outcomes in overt and subclinical hypothyroidism. Methods: We screened 1,005 antenatal patients for hypothyroidism with a thyrotropin assay. Patients diagnosed with hypothyroidism were further tested for anti-thyroid peroxidase antibodies and free thyroxin to determine the cause and type (overt or subclinical) of hypothyroidism. Maternal and perinatal outcomes were compared in the overt, subclinical and euthyroid groups. Results: The overall prevalence of hypothyroidism was 6.3% (overt 2.9% and subclinical 3.4%). Thirty-four (3.4%) new hypothyroid cases could be detected by universal screening. The risk factors for thyroid dysfunction were not significantly different in the screen-positive versus screen-negative patients except for excessive weight gain (p = 0.00). Targeted screening could have missed one third of subclinical hypothyroid cases. Gestational hypertension was significantly greater in the overt hypothyroid group (p = 0.007), and more patients required induction in this group (p = 0.013) but other maternal complications and perinatal outcomes were similar. Conclusion: We recommend universal screening for hypothyroidism in pregnancy in our population, as the prevalence of hypothyroidism is high.
Gynecologic and Obstetric Investigation 06/2012; 74(2):89-94. · 1.28 Impact Factor
-
[show abstract]
[hide abstract]
ABSTRACT: We sought to identify the characteristic features of pelvic tuberculosis (TB) in women with symptoms and sonogaphic findings which were otherwise consistent with an ovarian malignancy. This study is a retrospective analysis of 138 women who underwent an operation and had a preoperative diagnosis of ovarian malignancy at the Government Medical College Hospital, Chandigarh, from January 2004 to January 2008. Among these 138 women, seven cases (5.7%) of pelvic TB were identified. Abdominal pain and distension were the most common presenting symptoms. All patients had a pelvic mass, six had ascites (85%) and five had a fever (71%). The mean cancer antigen (CA) 125 level was 295 IU (13-529). Pelvic TB can present with symptoms and signs which mimic ovarian malignancy. Therefore, a high-index of clinical suspicion should be maintained when treating patients in countries with a high prevalence of TB.
Tropical Doctor 04/2012; 42(3):144-6. · 0.66 Impact Factor
-
[show abstract]
[hide abstract]
ABSTRACT: Scar endometriosis is a rare form of extrapelvic endometriosis that is usually confused with other surgical or dermatological conditions leading to delay in diagnosis.
We reviewed the case records of patients with the diagnosis of scar endometriosis seen in our hospital from January 1996 to December 2008.
We found six patients of scar endometriosis in 13 years making it one of the rare conditions. The median age of the patients was 32.5 years (range 28-37 years) and median interval from symptoms to treatment was 2 years (range 1-6 years). Four patients had first presented to either the surgery or dermatology physicians. Cyclic pain and swelling at local site was the most common presenting symptoms. All patients underwent wide excision of the mass with no recurrence of symptoms at a follow up ranging from 9 months to 12 years.
Increasing awareness of this condition among doctors can help in early diagnosis and treatment with gratifying results.
International journal of surgery (London, England) 01/2011; 9(1):39-40.
-
Journal of Obstetrics and Gynaecology Research 12/2010; 36(6):1265-6. · 0.94 Impact Factor
-
[show abstract]
[hide abstract]
ABSTRACT: Heterotopic pregnancy is diagnosed as the presence of two gestations simultaneously. This is a rare situation with a reported prevalence of 0.08% in normal conception.
We report a case of a 24-year-old primigravida of Indian origin who was seen in the emergency department with a diagnosis of a ruptured ectopic pregnancy. A careful ultrasound assessment led to the diagnosis of a heterotopic pregnancy. Immediate surgical intervention with supportive measures resulted in a successful outcome.
An obstetrician should keep in mind the occurrence of a heterotopic pregnancy while dealing with pregnant females. The ectopic gestation invariably ruptures over a period of time leaving the patient in an emergency situation. A quick assessment and careful handling of the normal gestation can lead the patient to term with gratifying results.
Journal of Medical Case Reports 01/2009; 3:8153.
-
MedGenMed: Medscape general medicine 02/2007; 9(4):44.
