Publications (2)3.2 Total impact
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Article: Breast cancer from oral and transdermal estradiol: a cohort study of Finnish women.
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ABSTRACT: Evaluation of: Lyytinen H, Pukkala E, Ylikorkala O: Breast cancer risk in postmenopausal women using estrogen-only therapy. Obstet. Gynecol. 108(6), 1354-1360 (2006) [1] . A cohort study of 84,729 Finnish women over the age of 50 years who used oral or transdermal estradiol for at least 6 months, followed for the incidence of breast cancer using a national cancer registry. The study was conducted to evaluate whether the risk of breast cancer with estrogen-only therapy varies by dose, constituents or route of administration. A total of 2171 women developed breast cancer, with no increased risk observed for less than 5 years of use, and some risk for greater than 5 years of use for both oral and transdermal routes of administration.Women s Health 05/2007; 3(3):321-4. -
Article: Current breast cancer risks of hormone replacement therapy in postmenopausal women.
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ABSTRACT: The controversies surrounding hormone replacement therapy have left many women confused and afraid. Providers have been faced with long-standing assumptions challenged by an abundance of new data in the past few years, with little guidance on how to interpret these findings. The objective of this paper is to provide a framework for understanding breast cancer risk associated with postmenopausal hormone replacement therapy, with a particular focus on how observational studies and randomised trials provide complementary information. This framework considers the data on risks of various hormonal preparations, the profiles of women at risk, and ends with an expert opinion in this context.Expert Opinion on Pharmacotherapy 01/2007; 7(18):2455-63. · 3.20 Impact Factor
Top Journals
Institutions
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2007
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New York University USA
- Division of Internal Medicine
New York City, NY, USA
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