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ABSTRACT: To assess the association between the single nucleotide polymorphism of the insulin receptor (INSR) gene and polycystic ovary syndrome (PCOS) in a Korean population.
One hundred seventy-four patients with PCOS and 93 healthy women as controls.
Frequency of three genotypes for single nucleotide polymorphism found in exon 17 of INSR gene.
The high frequency of the T allele was shown both in patient and control groups. The frequency of C allele, which known as a normal allele, was slightly higher in the patient group than in the control group.
The C/T polymorphism in exon 17 of the INSR gene is not associated with susceptibility of PCOS in a Korean population.
Fertility and sterility 09/2006; 86(2):380-4. · 3.97 Impact Factor