Zhengming Yang

Tongji Hospital, Wu-han-shih, Hubei, China

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Publications (2)2.36 Total impact

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    ABSTRACT: The authors performed a study to investigate the clinical manifestations, treatment strategies, and possible pathogenesis of conus medullaris schistosomiasis. Six cases collected from the authors' experience and four cases reported in the literature were studied retrospectively for clinical manifestations, treatment outcomes, and prognosis. All patients experienced progressive lower-extremity weakness and functional bowel and bladder impairment. Although the magnetic resonance (MR) imaging results suggested the presence of a conus medullaris tumor, schistosomiasis was diagnosed based on pathological results obtained in the 10 patients. The results of surgery followed by pyquiton and hormone treatment confirmed the diagnosis, and the patients' prognoses were good. This pathological entity is predominantly found in adults, and the clinical manifestations have no specificity, although the MR imaging may provide some clues. As a form of ectopic schistosomiasis, conus medullaris schistosomiasis deserves special consideration and further exploration. If an early diagnosis can be made and pyquiton and hormone therapy is given, surgery can be avoided and the prognosis will remain good.
    Journal of Neurosurgery Spine 09/2006; 5(2):146-9. DOI:10.3171/spi.2006.5.2.146 · 2.36 Impact Factor
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    ABSTRACT: ObjectiveTo determine the method and significance of facial nerve preservation during acoustic neurinoma surgery by intra-operative facial nerve monitoring (IFNM). Methods62 patients were randomly assigned to the IFNM or the control group. Facial nerve function (FNF) was assessed by a modified House-Brackmann grading (HB) before the operation, 10 days and every two months after surgery and compared between the two groups. ResultsTen days after surgery, 26/32 patients in the IFNM group and 15/30 patients in the control group had FNF HB grade I–III; FNF HB grade IV–V was present in 6/32 in the IFNM group and 15/30 in the control group. During follow-up, 29/32 patients in the IFNM group and 20/30 patients in the control group had FNF HB grade I–III; FNF HB grade IV–V was present in 3/32 in the IFNM group and 10/30 in the control group. All differences were statistically significant. ConclusionIFNM significantly improved anatomic and functional facial nerve preservation as well as the quality of life.
    The Chinese-German Journal of Clinical Oncology 09/2002; 1(3):168-169. DOI:10.1007/BF02851716