Jing Wang

Beijing University of Chemical Technology, Peping, Beijing, China

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Publications (385)441.26 Total impact

  • Source
    Annals of Dermatology 02/2014; 26(1):111-3. · 0.61 Impact Factor
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    ABSTRACT: A silicon-based micro-structure gas sensor for detecting formaldehyde was successfully fabricated and the sensing material was synthesized via a method of combining the traditional hydrothermal synthesis with subsequent heat treatment. Finite element analysis software of ANSYS was used to analyze the temperature distribution on the SiO2/Si substrate with heating electrodes and signal electrodes on the same plane with the aim of reducing the complexity of micro-machining process. Meanwhile, in order to obtain lower power consumption, two different structures of the SiO2/Si substrates with and without back etched were simulated, respectively. The simulation results showed that in the same heat rate and convection conditions, the back-etched SiO2/Si substrate had higher temperature, more uniform temperature distribution, and lower energy consumption. The Zn2SnO4/SnO2 cubes were obtained by annealing the as-synthesized precursors of ZnSn(OH)6 at 700 °C for 3 h. Thermal gravimetric and differential thermal analyzer, X-ray diffraction, Fourier transform infrared spectra, scanning electron microscopy, and energy-dispersive X-ray spectroscopy were analyzed to characterize the phase structure, composition, morphology, and elemental atomic ratio of Zn2SnO4/SnO2. The gas sensing properties of Zn2SnO4/SnO2 were tested, which showed that the gas sensor based on Zn2SnO4/SnO2 exhibited excellent formaldehyde sensing performance.
    Journal of Materials Science 01/2014; · 2.16 Impact Factor
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    ABSTRACT: Aims: This study was designed to investigate differences in genetic risk factors for rheumatoid arthritis (RA) in Han Chinese compared with Europeans. Methods: A genome-wide association study was conducted in China with 952 cases and 943 controls and 32 variants were followed up in 2132 cases and 2553 controls. A trans-population meta-analysis with results from a large European RA study was also performed to compare the genetic architecture across the two ethnic remote populations Results: Three non-MHC loci were identified at the genome-wide significance level, the effect sizes of which were larger in anti-citrullinated peptide antibody (ACPA) positive cases than those in ACPA-negative cases. These include two novel variants, rs12617656 located in an intron of DPP4 (odds ratio (OR) = 1.56, P = 1.6 × 10(-21) ) and rs12379034 located in the coding region of CDK5RAP2 (OR = 1.49, P = 1.1 × 10(-16) ), as well as a variant at the known CCR6 locus (rs1854853, OR = 0.71, P = 6.5 × 10(-15) ). The analysis of ACPA-positive cases vs. ACPA-negative cases revealed that rs12617656 at the DDP4 locus showed a strong interaction effect with ACPA (P = 5.3 × 10(-18) ) and such an interaction was also observed at the MHC locus (rs7748270, P = 5.9 × 10(-8) ). The trans-population meta-analysis showed genome-wide overlap and enrichment in association signals across the two populations, confirmed by prediction analysis. Conclusions: This study has expanded the risk alleles list of RA, provided new insight into the pathogenesis of RA, and added empirical evidence to the emerging polygenic nature of complex trait variation driven by common genetic variants. © 2013 American College of Rheumatology.
    Arthritis & Rheumatology 01/2014; · 7.48 Impact Factor
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    ABSTRACT: Multivariable control systems with colored noise widely exist in the most industrial fields, while the system identification under the closed loop conditions is needed in many cases. In view of the above two situations, it needs to find a convenient and effective method to solve the problem. Firstly, the design of the external input signals ensures the identifiability of closed loop system. Secondly, to make the direct method feasible for closed loop identification, the noise model selected is reasonably flexible and independently parameterized. On this basis, this paper proposes an improved method combining the direct closed loop identification approach with the iterative least squares parameter estimation algorithm, which can be an practical solution to the closed loop identification of multivariable systems with colored noise. The presented algorithm based hierarchical identification principle has a strong anti-jamming capability to effectively deal with colored noise existed in the system. Finally, the illustrative examples are given to demonstrate the effectiveness and accuracy of the proposed algorithm.
    Journal of Process Control 01/2014; · 1.81 Impact Factor
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    ABSTRACT: This paper examines the interaction of ammonia with Ag+-exchanged zeolite Y (Ag-Y) over a range of temperatures (250–450 °C). Impedance spectroscopy over the range of 0.5–107 Hz indicates that the Ag+ motion within the zeolite is facilitated in the presence of ammonia. Infrared spectroscopy and X-ray photoelectron spectroscopy indicate that Ag+single bondNH3 bonds are being formed. Temperature programmed desorption coupled with impedance spectroscopy show that the NH3 bonding to Ag+ is disrupted around 300 °C. However, in the presence of excess NH3, a fraction of the Ag+single bondNH3 bond survives up to 450 °C. Control experiments show that there is no measurable autoreduction of Ag+, and therefore, proton-mediated change of impedance in the presence of NH3 is not considered relevant. The change in mobility of the Ag+ in the presence of NH3 has been exploited to design an impedance-based NH3 sensor at a fixed frequency of 1000 Hz in the temperature range of 275–350 °C, with the optimal sensor response at 300 °C. No cross-sensitivity was observed for O2, CO, CO2 and propane. Nitric oxide showed minor interference. Water, however, did show an interference with a decrease in baseline impedance with increasing water. Thus, for practical applications of this sensor, the water content in the gas stream will need to be controlled to a constant value.
    Sensors and Actuators B Chemical 01/2014; 193:542. · 3.54 Impact Factor
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    Annals of Dermatology 11/2013; 25(4):508-10. · 0.61 Impact Factor
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    ABSTRACT: Toll-like receptor 4-mediated acute anterior uveitis is a serious ocular inflammatory disease, and new targeted drug therapy is the primary treatment. The objective of the present study was to investigate the molecular mechanism responsible for the activation of macrophages by rhubarb polysaccharides (RP) and try to find a new treatment for TLR4 pathway-mediated acute anterior uveitis. RAW264.7 macrophage cell lines were cultured in vitro, and rhubarb polysaccharides were used to stimulate the cell lines. An immunofluorescence technique was used to determine cell activation status by rhubarb polysaccharides; the ELISA technique was used to examine the production of cell supernatant inflammatory cytokines IL-1β, IFN-γ, IL-6, and TNF-α; and Western blot and real time RT-PCR were used to determine the effect of RP on TLR4, MyD88, and NF-κB p65 proteins and gene expression. Using Western blot, real time RT-PCR, ELISA, and immunofluorescence techniques, we found that rhubarb polysaccharides in vitro could activate macrophages; induce TLR4, MyD88, and NF-κB p65 protein and gene expression; and also induce the production of cytokines IL-1β, IFN-γ, IL-6, and TNF-α. The results presented in this report suggest that RP induce macrophage activation through the TLR4/NF-ΚB signaling pathway. Our data suggest that RP have the potential to be used for their immunostimulatory effect in the treatment of infectious diseases such as TLR4-mediated acute anterior uveitis.
    International immunopharmacology 11/2013; · 2.21 Impact Factor
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    ABSTRACT: Titania-doped chromium oxide (CTO) can serve as an active gas-sensing material. It has been successful in commercial gas sensors due to its good gas-sensing performance and stability in humid environment; especially with respect of volatile organic compounds (VOCs). CTO fibers with reticular structure were prepared by electrospinning technology and the sensing behavior upon exposure to ethanol was characterized in this report. The gas sensors made of CTO fibers show a good response to ethanol and stability for a long term at operating temperature of 400°C. The experimental results have been analyzed and simulated using the response equations. The humidity effects on the sensor performance were also evaluated. The results indi-cate that the CTO fibers could be used in practical applications.
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    ABSTRACT: The large-scale array antenna system with numerous low-power antennas deployed at the base station, also known as massive multiple-input multiple-output (MIMO), can provide a plethora of advantages over the classical array antenna system. Precoding is important to exploit massive MIMO performance, and codebook design is crucial due to the limited feedback channel. In this paper, we propose a new avenue of codebook design based on a Kronecker-type approximation of the array correlation structure for the uniform rectangular antenna array, which is preferable for the antenna deployment of massive MIMO. Although the feedback overhead is quite limited, the codebook design can provide an effective solution to support multiple users in different scenarios. Simulation results demonstrate that our proposed codebook outperforms the previously known codebooks remarkably.
    International Journal of Antennas and Propagation 10/2013; 2013. · 0.68 Impact Factor
  • Journal of dermatological science 06/2013; · 3.71 Impact Factor
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    ABSTRACT: Distributed MIMO (D-MIMO) system is one of the candidates for future wireless access networks. In this study, the spatial correlation and capacity in indoor D-MIMO system are presented. All results are from the actual channel measurements in typical indoor scenarios, including office and corridor. Based on measured data, spatial correlation coefficients between distributed transmitting antennas are analyzed. Although the literature about D-MIMO system assumes the small scale fading between distributed antennas is independent, we find that spatial correlation may still exist in specific propagation scenario. This correlation can also degrade the performance of D-MIMO system. To mitigate the impact of spatial correlation, one efficient method is to use transmitting antenna selection technique.
    International Journal of Antennas and Propagation 06/2013; 2013. · 0.68 Impact Factor
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    ABSTRACT: Non-obstructive azoospermia (NOA) is considered to be a severe infertility factor due to impaired spermatogenesis with the consequent absence of spermatozoa in the ejaculate. However, the underlying etiology and mechanism(s) remain elusive. The aim of this study was to investigate the mutation and association of single nucleotide polymorphisms (SNPs) of the phosphoglycerate mutase 4 (PGAM4) gene in Chinese Han infertile men with NOA. The entire coding region of PGAM4 gene was sequenced from 214 participants including 103 infertile men with NOA and 111 controls with proven fertility. Screening was carried out using PCR and DNA sequencing to identify novel mutations and SNPs of the entire coding region of PGAM4. No mutation, including A138C or G539A, was detected in the coding region of PGAM4. One novel synonymous mutation (G111A, rs20100573) in control individuals was identified. There was no significant difference between NOA patients and controls in the G75C (rs138178131) frequencies (1.9% (2/103) and 4.5% (5/111), respectively, P = 0.292 and P = 0.374, adjusted by age). PGAM4 coding region mutations were not observed and the G75C polymorphism is not associated with NOA susceptibility among the Chinese Han population.
    Systems biology in reproductive medicine 05/2013; · 1.85 Impact Factor
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    ABSTRACT: The Drosophila Eyes Absent Homologue 1 (EYA1) is a component of the retinal determination gene network (RDGN) and serves as an H2AX phosphatase. The cyclin D1 gene encodes the regulatory subunits of a holoenzyme that phosphorylates and inactivates the pRb protein. Herein, comparison with normal breast demonstrated EYA1 is overexpressed with cyclin D1 in luminal B breast cancer subtype. EYA1 enhanced breast tumor growth in mice in vivo requiring the phosphatase domain. EYA1 enhanced cellular proliferation, inhibited apoptosis, and induced contact-independent growth and cyclin D1 abundance. The induction of cellular proliferation and cyclin D1 abundance, but not apoptosis, was dependent upon the EYA1 phosphatase domain. The EYA1-mediated transcriptional induction of cyclin D1 occurred via the AP-1 binding site at -953 and required the EYA1 phosphatase function. The AP-1 mutation did not affect SIX1-dependent activation of cyclin D1. EYA1 was recruited in the context of local chromatin to the cyclin D1 AP-1 site. The EYA1 phosphatase function determined the recruitment of CBP, RNA polymerase II and acetylation of H3K9 at the cyclin D1 gene AP-1 site regulatory region in the context of local chromatin. The EYA1 phosphatase regulates cell cycle control via transcriptional complex formation at the cyclin D1 promoter.
    Cancer Research 05/2013; · 8.65 Impact Factor
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    ABSTRACT: To compare the bactericidal efficacy of two different cold plasma (glow discharge and dielectric barrier discharge) treatments on root canal infected with Enterococcus faecalis biofilms in vitro. One hundred and twenty teeth infected with Enterococcus faecalis biofilm in the roots for seven days were divided into twelve groups randomly. Two served as negative control group (gas only, no discharge). Five were teeth treated by dielectric barrier discharge cold plasma and the other five were treated by glow discharge cold plasma. The treatment time in each five groups was 2, 4, 6, 8 and 10 min, respectively. The disinfection of Enterococcus faeccalis biofilm was evaluated by colony forming unit (CFU) counting. The plasma component produced by different devices was analyzed by optical emission spectroscopy (OES). Comparing the two plasma treatments, the plasma produced by dielectric barrier discharge had better bactericidal effect than that produced by glow discharge at different treatment time (P < 0.05). The advantage was obvious with the time getting longer. The OES indicated that active components of the two type plasmas were similar. But the peak of excited Ar atom of dielectric barrier discharge was twice as that of glow discharge. The cold plasma produced by dielectric barrier discharge has more bactericidal efficiency in the treatment of root canal infected with Enterococcus faecalis biofilms.
    Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 04/2013; 31(2):195-8.
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    ABSTRACT: Hyperactive EGFR and mutant p53 are common genetic abnormalities driving the progression of non-small cell lung cancer (NSCLC), the leading cause of cancer deaths in the world. The Drosophila gene Dachshund (Dac) was originally cloned as an inhibitor of hyperactive EGFR alleles. Given the importance of EGFR signaling in lung cancer etiology, we examined the role of DACH1 expression in lung cancer development. DACH1 protein and mRNA expression was reduced in human NSCLC. Re-expression of DACH1 reduced NSCLC colony formation and tumor growth in vivo via p53. Endogenous DACH1 co-localized with p53 in a nuclear, extranucleolar location, and shared occupancy of -15% of p53 bound genes in ChIP Seq. The C-terminus of DACH1 was necessary for direct p53 binding, contributing to the inhibition of colony formation and cell cycle arrest. Expression of the stem cell factor SOX2 was repressed by DACH1, and SOX2 expression was inversely correlated with DACH1 in NSCLC. We conclude that DACH1 binds p53 to inhibit NSCLC cellular growth.
    Cancer Research 03/2013; · 8.65 Impact Factor
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    ABSTRACT: This paper investigates the distributed power allocation problem for coordinated multipoint (CoMP) transmissions in distributed antenna systems (DAS). Traditional duality based optimization techniques cannot be directly applied to this problem, because the non-strict concavity of the CoMP transmission's achievable rate with respect to the transmission power induces that the local power allocation subproblems have non-unique optimum solutions. We propose a distributed power allocation algorithm to resolve this non-strict concavity difficulty. This algorithm only requires local information exchange among neighboring base stations serving the same user, and is thus scalable as the network size grows. The step-size parameters of this algorithm are determined by only local user access relationship (i.e., the number of users served by each antenna), but do not rely on channel coefficients. Therefore, the convergence speed of this algorithm is quite robust to different channel fading coefficients. We rigorously prove that this algorithm converges to an optimum solution of the power allocation problem. Simulation results are presented to demonstrate the effectiveness of the proposed power allocation algorithm.
    IEEE Transactions on Wireless Communications 03/2013; · 2.42 Impact Factor
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    ABSTRACT: Background: Genetic factors are involved in the etiology of Mycobacterium tuberculosis infection. Recently, ALOX5 has been identified as a candidate gene for tuberculosis (TB) susceptibility. We investigated whether an association between ALOX5 and TB exists in a Chinese pediatric population from northern China. Methods: We conducted a case-control study comprising 488 individuals aged 2 months to 17 years by genotyping 18 tag-single-nucleotide polymorphisms (SNPs) from the ALOX5 gene. The tag-SNPs were selected from the international HapMap project. An Illumina BeadXpress Scanner was utilized for genotyping, supported by the high-density BeadArray technology in combination with an allele-specific extension, adapter ligation, and amplification assay. Statistical analyses were performed to determine correlations between genetic variation and disease. Results: Our study is the first to show that ALOX5 is associated with susceptibility to pediatric TB in a subset of children in northern China. The rs2115819 T allele of ALOX5 presents a risk factor for childhood TB disease.
    Genetic Testing and Molecular Biomarkers 02/2013; · 1.44 Impact Factor
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    ABSTRACT: Optimal power allocation for orthogonal frequency division multiplexing (OFDM) wiretap channels with Gaussian channel inputs has already been studied in some previous works from an information theoretical viewpoint. However, these results are not sufficient for practical system design. One reason is that discrete channel inputs, such as quadrature amplitude modulation (QAM) signals, instead of Gaussian channel inputs, are deployed in current practical wireless systems to maintain moderate peak transmission power and receiver complexity. In this paper, we investigate the power allocation and artificial noise design for OFDM wiretap channels with discrete channel inputs. We first prove that the secrecy rate function for discrete channel inputs is nonconcave with respect to the transmission power. To resolve the corresponding nonconvex secrecy rate maximization problem, we develop a low-complexity power allocation algorithm, which yields a duality gap diminishing in the order of O(1/\sqrt{N}), where N is the number of subcarriers of OFDM. We then show that independent frequency-domain artificial noise cannot improve the secrecy rate of single-antenna wiretap channels. Towards this end, we propose a novel time-domain artificial noise design which exploits temporal degrees of freedom provided by the cyclic prefix of OFDM systems {to jam the eavesdropper and boost the secrecy rate even with a single antenna at the transmitter}. Numerical results are provided to illustrate the performance of the proposed design schemes.
    IEEE Transactions on Wireless Communications 02/2013; 12(6). · 2.42 Impact Factor
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    ABSTRACT: To investigate the tooth bleaching effect of a low con-centration hydrogen peroxide (H 2 O 2) assisted by a nonthermal plasma, extracted human teeth were treated by a nonthermal plasma in the presence of varying concentrations of hydrogen peroxide gel. The results showed that combining plasma treatment with a low concentration hydrogen peroxide (6%) achieved a superior bleaching effect compared with a high concentration of hydrogen peroxide (35%) in the absence of a plasma. Further-more, the bleaching efficacy did not significantly increase with increasing H 2 O 2 concentration above 6% in the presence of the plasma. Compared with the control group (hydrogen peroxide without plasma), the plasma generated two to three times as many ·OH radicals, which are believed to be one of the key reactive species that contribute to the bleaching effect.
    IEEE Transactions on Plasma Science 02/2013; 41:325. · 0.87 Impact Factor
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    ABSTRACT: We fabricated a plasmonic analog of the microwave microstrip transmission line and measured its propagation loss before and after thermal annealing. It is found that its propagation loss at 980 nm wavelength can be reduced by more than 50%, from 0.45 to 0.20 dB/μm, after thermal annealing at 300 °C. The reduction in loss can be attributed to the improved gold surface condition and probably also to the change in the metal's inner structure. Less evident loss reduction is noticed at 1550 nm, which is owing to extremely small portion of the modal electric field located in the metal regions at this wavelength.
    Optics Express 01/2013; 21(2):1639-44. · 3.55 Impact Factor

Publication Stats

1k Citations
441.26 Total Impact Points


  • 2012–2014
    • Beijing University of Chemical Technology
      Peping, Beijing, China
    • Beijing Medical University
      • Department of Radiology
      Peping, Beijing, China
    • Shenyang Pharmaceutical University
      Feng-t’ien, Liaoning, China
    • Anhui Medical University
      • Institute of Dermatology
      Luchow, Anhui Sheng, China
    • Lanzhou University
      • School of Stomatology
      Lanzhou, Gansu Sheng, China
  • 2004–2014
    • Dalian University of Technology
      • • School of Electronic and Information Engineering
      • • Department of Electronic Engineering
      Lü-ta-shih, Liaoning, China
    • University of Texas Medical Branch at Galveston
      • Department of Neuroscience and Cell Biology
      Galveston, TX, United States
  • 2013
    • Hui Zhou University
      Kao-lan-hsien, Gansu Sheng, China
    • Wannan Medical College
      Wu-hu-shih, Anhui Sheng, China
  • 2012–2013
    • Beijing University of Posts and Telecommunications
      • State Key Laboratory of Switching and Networking
      Peping, Beijing, China
  • 2011–2013
    • Tongji Hospital
      Wu-han-shih, Hubei, China
    • Dalian Ocean University
      Lü-ta-shih, Liaoning, China
  • 2008–2013
    • Huazhong University of Science and Technology
      Wu-han-shih, Hubei, China
    • Samsung
      Sŏul, Seoul, South Korea
  • 1–2013
    • Tsinghua University
      • Department of Electronic Engineering
      Peping, Beijing, China
  • 2011–2012
    • Capital Medical University
      • Department of Ophthalmology
      Peping, Beijing, China
  • 2009–2012
    • Peking Union Medical College Hospital
      Peping, Beijing, China
    • Peking University
      • • Academy for Advanced Interdisciplinary Studies
      • • Department of Chemical Biology
      Beijing, Beijing Shi, China
    • Shanghai Jiao Tong University
      • Department of Electronic Engineering
      Shanghai, Shanghai Shi, China
    • Renmin University of China
      Peping, Beijing, China
  • 2008–2012
    • Liaoning Research Institute of Family Planning
      Feng-t’ien, Liaoning, China
  • 2010–2011
    • Harbin Medical University
      Charbin, Heilongjiang Sheng, China
    • Tianjin Medical University Cancer Institute and Hospital
      T’ien-ching-shih, Tianjin Shi, China
  • 2009–2011
    • KTH Royal Institute of Technology
      • • School of Information and Communication Technology (ICT)
      • • Department of Microelectronics and Applied Physics (MAP)
      Stockholm, Stockholm, Sweden
  • 2008–2011
    • Beijing Genomics Institute
      Bao'an, Guangdong, China
  • 2008–2009
    • Nokia Siemens Networks
      Esbo, Southern Finland Province, Finland
  • 2007–2009
    • Nanjing University
      • Department of Chemical Engineering
      Nanjing, Jiangsu Sheng, China
    • Southeast University (China)
      Nan-ching-hsü, Jiangxi Sheng, China
    • Northeast Institute of Geography and Agroecology
      • Institute of High Energy Physics
      Beijing, Beijing Shi, China
  • 2006
    • Tongji Medical University
      • Department of Immunology
      Wu-han-shih, Hubei, China
  • 2002–2006
    • Louisiana Tech University
      • Institute for Micromanufacturing
      Ruston, LA, United States
  • 2005
    • University of Minnesota Twin Cities
      • Department of Mechanical Engineering
      Minneapolis, MN, United States
  • 2003–2004
    • Chinese Academy of Sciences
      • Condensed Matter Physics
      Beijing, Beijing Shi, China