[Show abstract][Hide abstract] ABSTRACT: Healthy, young individuals are known to exhibit circadian variation in urinary functions. However, the effects of chronic circadian disturbance on voiding functions are largely unknown. The present work compared the effects of rotational shifts on the micturition patterns of female nurses to that in female nurses with routine daytime shifts.
A total of 19 nurses without lower urinary tract symptoms who worked rotational shifts for an average duration of 2 years were recruited. A voiding diary was kept for 9 consecutive days, and the overactive bladder symptom score (OABSS) questionnaire was completed three times, starting 3 days before their night duties until 3 days after completion of their night duties. For comparison, seven nurses with regular shifts completed a 3-day voiding diary and the OABSS questionnaire.
Female nurses working rotational shifts had lower overall urine production and had decreased urination frequency and nocturia than female nurses working regular shifts, even when the nurses who worked rotational shifts had a regular night's sleep for at least 7 days. Upon reinitiation of night duty, overall urine production increased significantly, with no significant changes in urgency and frequency. When these nurses returned to daytime duty, the volume of urine decreased but nocturnal urine production remained high, and the incidence of nocturia also increased significantly. However, the effects on OABSS score were not significant under the study design used.
Long-term rotational shifts resulted in adaptive changes such as decreased urine production and frequency in healthy, young female nurses. In addition, their micturition patterns were significantly affected by abrupt changes in their work schedules. Although working in shifts did not increase urgency or frequency of urination in healthy, young female nurses working rotational shifts for an average 2 years, large-scale studies are needed to systematically analyze the influence of shift work timings on micturition in humans.
International neurourology journal 12/2014; 18(4):206-12. DOI:10.5213/inj.2014.18.4.206
[Show abstract][Hide abstract] ABSTRACT: Purpose: We aimed to evaluate the technical feasibility, safety and physiologic impacts of transvaginal (TV) and transrectal (TR) natural orifice transluminal endoscopic surgery (NOTES) nephrectomy compared with conventional laparoscopic nephrectomy in a porcine survival model. Patients and Methods: A total of 15 female pigs weighing 30 to 35 kg were randomized to receive TV NOTES nephrectomy (n=5), TR NOTES nephrectomy (n=5) or conventional laparoscopic nephrectomy (n=5). Postoperatively, all pigs recovered and were monitored for well-being during convalescence. Several laboratory parameters and inflammatory cytokines were compared among the groups during the entire observation period. Re-exploration was performed 1 week after surgery for evaluation of intraperitoneal complications and cultures for microorganisms. Results: All procedures were performed successfully without additional trocar insertion or any kind of conversion. Although total operation times were longer for TV and TR NOTES nephrectomy than for laparoscopic nephrectomy (61 vs. 84 vs. 24 min, p<0.001), there was no evidence of peritonitis, intraperitoneal abscess, bleeding, or organ injury on re-exploration. None of the laboratory parameters, including white blood cell count, TNF-α, IL-1, and IL-6 differed among the groups during the observational period. Conclusions: Transvaginal and transrectal NOTES nephrectomy could be performed successfully with similar physiologic impacts to those of conventional laparoscopic nephrectomy in a porcine survival model.
Journal of endourology / Endourological Society 10/2014; 29(3). DOI:10.1089/end.2014.0309 · 2.10 Impact Factor
[Show abstract][Hide abstract] ABSTRACT: A V-grooved single-mode optical fiber is proposed as a multipoint liquid detection sensor, and its feasibility is demonstrated using optical time domain reflectometry (OTDR). The optical mode is affected by an external medium covering the V-grooved region due to the exposed fiber core. As a result, it is possible to detect the leakage of liquid and position of events through monitoring the transmission and reflection signal of OTDR.
[Show abstract][Hide abstract] ABSTRACT: The safety and efficacy of laparoendoscopic single-site surgery (LESS) for renal cell carcinoma (RCC) have not been clearly demonstrated. We aimed to present preliminary data from a prospective randomized controlled trial of LESS versus conventional laparoscopic radical nephrectomy for localized RCC.
Patients with cT1-2 RCC were randomized to LESS (n = 17) or conventional laparoscopy (n = 18) group. The short-term outcome measures assessed were perioperative morbidity, postoperative pain, and quality of recovery as determined using QoR-40.
No significant differences were observed between the LESS and conventional laparoscopy groups with respect to operative time (143.5 vs. 126.1 min, p = 0.218), blood loss (143.6 vs. 118.2 ml, p = 0.121), hospital stay (3.8 vs. 3.1 day s, p = 0.170), analgesic requirements (63.2 vs. 60.0 mg, p = 0.956), and complication rates (26.7 vs. 22.2 %, p = 0.767). However, postoperative quality of recovery was better in the LESS group (176.4 vs. 152.6, p = 0.005). Furthermore, quality of recovery, as measured using the QoR-40 dimensions of emotional state (39.9 vs. 34.0, p = 0.003), physical comfort (51.9 vs. 46.7, p = 0.034), psychological support (32.2 vs. 25.8, p = 0.003), and physical independence (20.7 vs. 17.5, p = 0.047), but not pain (31.8 vs. 29.6, p = 0.259), was significantly better in the LESS group.
The preliminary results from this prospective trial suggest that LESS could be a safe and effective treatment option for localized RCC with equivalent surgical outcomes and improved postoperative quality of recovery compared with conventional laparoscopic surgery.
World Journal of Urology 05/2014; 33(3). DOI:10.1007/s00345-014-1322-5 · 3.42 Impact Factor
[Show abstract][Hide abstract] ABSTRACT: In this paper, a measurement method to obtain the optical properties of a liquid base on a side-polished single mode fiber was proposed and demonstrated. The device showed periodic resonance coupling against wavelengths. The refractive index and dispersion characteristics of a liquid were calculated by use of the spacings of periodic resonance wavelengths of the device. The thermo-optic coefficient of the liquid was obtained by monitering the shift of resonance wavelengths of the devices with change of environmental temperature.
[Show abstract][Hide abstract] ABSTRACT: We aimed to describe the surgical technique of hand-assisted retroperitoneoscopic nephroureterectomy (HARNU) with bladder cuffing after preperitoneal and retroperitoneal perivesical ballooning.
From March 2008 to September 2012, we performed HARNU and open bladder cuffing in 28 consecutive series of patients with upper urinary tract urothelial carcinoma. We performed HARNU according to the following procedure: (1) a camera port incision was made on the posterior axillary line; (2) multiple, repeated, preperitoneal and retroperitoneal ballooning was performed on both the posterior axillary line and in the umbilicus; (3) a 7.0 cm skin incision was made from the suprapubic to the lower inguinal with the balloon present in the extraperitoneal area; (4) hand-assisted laparoscopic retroperitoneal nephroureterectomy; (5) cessation of gas insufflation; and (6) extravesical cuffing as an open surgical procedure.
The mean estimated blood loss was 250 mL. The mean operation time was 240 minutes. The mean time to oral intake and ambulation was 1.0 day and two days, respectively. As for postoperative complications due to the hand-assisted device, one patient developed febrile urinary tract infection within three weeks postoperatively and was hospitalized again to receive parenteral antibiotics.
We made a low Gibson incision for a route for the hand-assisted procedure as well as a window for open surgery in dissecting the distal ureter and extracting the surgical specimens. Thus, our results indicate that the HARNU might be a feasible surgical modality.
Korean journal of urology 01/2014; 55(1):29-35. DOI:10.4111/kju.2014.55.1.29
[Show abstract][Hide abstract] ABSTRACT: Tubeless percutaneous nephrolithotomy (PNL) remains a challenging technique for the surgical treatment of staghorn renal calculi. Our study was designed to compare surgical outcomes between conventional and tubeless PNL.
We retrospectively enrolled consecutive patients who underwent conventional or tubeless PNL under general anesthesia performed by a single surgeon (H.J.) for the treatment of staghorn calculi between 2003 and 2012. All patients were divided into two groups: group 1 included patients who underwent conventional PNL and group 2 included patients who were managed by tubeless PNL for the treatment of staghorn calculi. Preoperative and postoperative parameters were analyzed between the two groups, including age, stone burden, complications, any interventions, and duration of hospital stay.
A total of 165 patients (group 1, 106; group 2, 59) were enrolled in the study. No significant differences in age, sex, body mass index, or stone laterality were observed between the two groups. The mean stone burdens (±standard deviation) of group 1 and group 2 were 633.6 (±667.4) and 529.9 (±362.8), respectively (p=0.271). The postoperative stone-free clearance rate was higher in group 2 (78.0%) than in group 1 (69.8%); however, the difference was not clinically significant (p=0.127). In addition, no significant differences in postoperative complications, including fever, bleeding, infection, or additional interventions, were observed between the two groups.
Our results demonstrated that tubeless PNL has the same effectiveness and safety as conventional PNL in the treatment of staghorn calculi. Tubeless PNL may be feasible for managing renal staghorn calculi.
Korean journal of urology 10/2013; 54(10):693-6. DOI:10.4111/kju.2013.54.10.693
[Show abstract][Hide abstract] ABSTRACT: We proposed and demonstrated a distributed fiber-optic overheating detection sensor using optical time domain refrectometry. With increased of temperature the optical fiber is bended by a bi-metal and it result in optical leaky loss of the fiber. The sensor structure is designed in such a way that the signal of overheating is happen when the temperature exceeding a threshold temperature and the optical fiber is protected from excess bending.
[Show abstract][Hide abstract] ABSTRACT: This study proposed and demonstrated a fiber Bragg grating sensor for simultaneous detection of the temperature and refractive index of a liquid. The fiber Bragg grating is composed of three index layers: an inner core, an outer core, and a cladding. The cladding was etched for evanescent wave coupling between the outer core mode and an external liquid. The Bragg wavelength of the inner core mode is used for obtaining temperature data, while the refractive index for the liquid was determined by using the difference between the Bragg wavelength of the inner core mode and that of outer core mode.