C. Carpentieri

Università di Pisa, Pisa, Tuscany, Italy

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Publications (7)4.3 Total impact

  • Article: A pixel detector-based single photon-counting system as fast spectrometer for diagnostic X-ray beams.
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    ABSTRACT: Recent advances in semiconductor pixel detectors and read-out electronics allowed to build the first prototypes of single photon-counting imaging systems that represent the last frontier of digital radiography. Among the advantages with respect to commercially available digital imaging systems, there are direct conversion of photon energy into electrical charge and the effective rejection of electronic noise by means of a thresholding process. These features allow the photon-counting systems to achieve high imaging performances in terms of spatial and contrast resolution. Moreover, the now available deep integration techniques allow the reduction of the pixel size and the improvement of the functionality of the single cell and the read-out speed so as to cope with the high fluxes found in diagnostic radiology. In particular, the single photon-counting system presented in this paper is based on a 300-microm thick silicon pixel detector bump-bonded to the Medipix2 read-out chip to form an assembly of 256 x 256 square pixels at a pitch of 55 microm. Each cell comprises a low-noise preamplifier, two pulse height discriminators and a 14-bit counter. The maximum counting rate per pixel is 1 MHz. The chip can operate in two modalities: it records the events with energy above a threshold (single mode) or between two energy thresholds (window mode). Exploiting this latter feature, a possible application of such a system as a fast spectrometer is presented to study the energy spectrum of diagnostic beams produced by X-ray tubes.
    Radiation Protection Dosimetry 06/2008; 129(1-3):119-22. · 0.82 Impact Factor
  • Article: Dental radiology dosimetric data as routinely collected in an Italian hospital.
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    ABSTRACT: The work presented here was developed in the framework of the SENTINEL Project and is devoted to the analysis of dental radiology dosimetric data. The procedure of data processing allows the analysis of some important aspects related to the protection of the patient and the staff because of the position of the operators near the patient and their exposure to the radiation scattered by the patient. Dental radiology data was collected in an Italian hospital. Following the Italian quality assurance (QA) protocols and suggestions by the leaders of the SENTINEL Project, X-ray equipment performances have been analysed in terms of: kVp accuracy, exposure time accuracy and precision, tube output, dose reproducibility and linearity, beam collimation, artefacts and light tightness. Referring to these parameters the physical quality index (QI) was analysed. In a single numerical value between 0 and 1, QI summarises the results of quality tests for radiological devices. The actual impact of such a figure (as suggested by international QA protocols or as adopted by local QA routine) on the policy of machine maintenance and replacement is discussed.
    Radiation Protection Dosimetry 04/2008; 129(1-3):227-30. · 0.82 Impact Factor
  • Article: Characterization of a Single Photon Counting Imaging System by Transfer Function Analysis
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    ABSTRACT: A method to quantitatively evaluate the performances of a radiographic detection system consists in measuring the contrast, noise and modulation transfer functions. These functions have been evaluated for a digital radiographic system based on a single photon counting pixel detector. The X-ray detector is a Silicon sensor with one side segmented in a matrix of 256 by 256 square contacts with a pitch of 55 mum. The active area is about 2 cm<sup>2</sup>. The sensor is connected to the Medipix2 read-out chip by bump-bonding. As X-ray source we have used a tube for general radiography. To reproduce the conditions of a radiographic examination, a 4 cm thick lucite block positioned above the detector has been used to simulate a tissue sample. To study the Contrast Transfer Function we have measured the contrast of an 1 mm thick lead slab with respect to the background. To evaluate the scattering contribution from the lucite, the measurements have been performed with and without a collimator placed at the beam exit. To assess the efficiency and noise transfer properties, we have measured the Detective Quantum Efficiency (DQE) of the detector as a function of the tube voltage. The Modulation Transfer Function has been measured applying the slit method for different conditions of tube voltage and energy threshold
    IEEE Transactions on Nuclear Science 03/2007; · 1.45 Impact Factor
  • Conference Proceeding: Characterization of a single photon counting imaging system by the transfer functions analysis
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    ABSTRACT: A method to quantitatively evaluate the performances of a radiographic detection system consists on measuring the contrast, noise and modulation transfer functions. These functions have been evaluated for a digital radiographic system based on a single photon counting pixel detector. The X-ray detector is a silicon sensor with one side segmented in a matrix of 256 by 256 square contacts with a pitch of 55 μm. The active area is about 2 cm<sup>2</sup>. The sensor is connected to the Medipix2 read-out chip by bump-bonding. As X-ray source we used a tube for general radiography. To reproduce the conditions of a radiographic examination a 4 cm thick lucite block positioned above the detector has been used to simulate a tissue sample. To study the contrast transfer function we have measured the contrast of 1 mm thick lead slab with respect to the background. To evaluate the scattering contribution from the lucite, the measurements have been performed with and without a collimator placed at the beam exit. To assess the efficiency and noise transfer properties, we have measured the detective quantum efficiency (DQE) of the detector as a function of the tube voltage. The modulation transfer function has been measured applying the slit method for different conditions of tube voltage and energy threshold.
    Nuclear Science Symposium Conference Record, 2005 IEEE; 11/2005
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    Article: Preliminary study of the advantages of X-ray energy selection in CT imaging
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    ABSTRACT: It is well known that a monochromatic X-ray source with an energy optimized for the organ thickness to be imaged could result in a better image quality in transmission radiology. In this paper we present the preliminary investigation for the implementation of this technique in computer tomography (CT) imaging. The detection system is based on a 1 mm thick silicon pixel detector bump bonded to a VLSI read-out, Medipix2. This detector ensures a good detection efficiency (46%) in the used energy range (60 kVp) with a good spatial resolution that arises from a 55 μm square pixel. The Medipix2 read-out electronics is not only a single photon counting system, but has also the capability of dual-energy threshold, that allows us to detect only photons that are in a chosen energy window. In this paper we present the results obtained in CT imaging of small samples, by selecting various energy windows within a standard X-ray tube spectrum so as to maximize the differentiation between significant attenuation coefficients. This study is preliminary for a future development of a dual-energy CT that could add functional information to the morphological information that is obtained in a CT examination.
    Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment 572(1):270-273. · 1.21 Impact Factor
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    Article: Characterization of a high-resolution CT scanner prototype for small animals
    Nuovo Cimento B Serie. 122:739-747.
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    Article: Preliminary characterization of a single photon counting detection system for CT application
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    ABSTRACT: The aim of this work is to evaluate the capability of a single photon counting acquisition system based on the Medipix2 read-out chip for Computed Tomography (CT) applications in Small Animal Imaging. We used a micro-focus X-ray source with a W anode. The detection system is based on the Medipix2 read-out chip, bump-bonded to a 1 mm thick silicon pixel detector. The read-out chip geometry is a matrix of 256×256 cells, 55 μm×55 μm each. This system in planar radiography shows a good detection efficiency (about 70%) at the anode voltage of 30 kV and a good spatial resolution (MTF=10% @ 16.8 lp/mm). Starting from these planar performances we have characterized the system for the tomography applications with phantoms. We will present the results obtained as a function of magnification with two different background medium compositions. The effect of the reconstruction algorithm on image quality will be also discussed.
    Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 576(1):204 - 208.