ABSTRACT: To study the value of serum S100 protein in the diagnosis of radiation-induced brain injury in astrocytoma patients.
Serum S100 protein levels were detected by enzyme-linked immunosorbent assay in 86 astrocytoma patients in the course of radiotherapy.
The positivity rates of serum S100 protein before, in the middle of and after radiotherapy were 0, 9.3% (8/86) and 19.8% (17/86), respectively, showing significant differences (P<0.05) between these time points for measurement.
High levels of serum S100 protein are associated with radiation-induced brain injury in astrocytoma patients and may serve as the marker for early diagnosis of the injury.
Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 06/2005; 25(6):723-5.