Patrick Angibaud,
Janine Arts,
Kristof Van Emelen,
Virginie Poncelet,
Isabelle Pilatte,
Bruno Roux,
Sven Van Brandt,
Marc Verdonck,
Hans De Winter,
Peter Ten Holte, [......],
Boudewijn Janssens,
Jacky Van Dun,
An Aerts,
Jacky Van Gompel,
Sandrine Gaurrand,
Laurence Queguiner,
Jean-Michel Argoullon, Luc Van Hijfte,
Eddy Freyne,
Michel Janicot
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ABSTRACT: A series of pyrimidyl-5-hydroxamic acids was prepared for evaluation as inhibitors of histone deacetylase (HDAC). Amino-2-pyrimidinyl can be used as a linker to provide HDAC inhibitors of good enzymatic potency.
European Journal of Medicinal Chemistry 07/2005; 40(6):597-606. · 3.35 Impact Factor