Publications (2)0 Total impact
Article: [Osteoarthritis secondary to the developmental hip dysplasia-treatment options in young patients].[show abstract] [hide abstract]
ABSTRACT: The choice of the treatment method in young patients with osteoarthritis secondary to the developmental hip dyplasia is one of the most difficult dilemmas in orthopaedic practice. Currently total cementless hip replacement with metal-on-metal articulation is a routine procedure. Young patients are particularly exposed to the risk of aseptic loosening due to their high activity and long duration of life with implant. Basing on our material, using selected clinical cases, options for treatment of OA secondary to DHD were presented. The paper presents the progress of OA seconary to DHD treated in childhood and its subsequent treatment using intertrochanteric osteotomy without changing the neck-shaft angle, intertrochanteric osteotomy combined with shelf procedures, isolated shelf procedures and periacetabular osteotomies according to Ganz. Both satisfactory results with pain relief for any years so like negative ones with total lack of improvement were shown. Presented options for treatment alternative to THR may be helpful in determining the individual management in young adults.Chirurgia narzadow ruchu i ortopedia polska 02/2005; 70(5):325-9.
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ABSTRACT: Polymorphonuclear neutrophils (PMN) are the first cells to take part in the local foreign body reaction in aseptic loosening of endoprostheses. The aim of this study was to evaluate the systemic host reaction to total joint replacement by measuring the production of nitric oxide by neutrophils before and after total joint replacement. Blood samples were collected from 33 patients (27 hips and 6 knees) before surgery, and 2 weeks, 2 months and 2.5-3 years after surgery. The levels of nitric oxide produced by PMN were measured by the method described by Markert et al. (1994). Patients reporting pain in the region of the implant 3 years after surgery, and also patients with radiographic signs of loosening, had higher production of NO in the early period and 3 years after the implantation than those with good clinical results. We propose that elevated levels of nitric oxide production by PMNs may serve as a marker of total joint prosthesis loosening.Acta Orthopaedica Scandinavica 10/2004; 75(5):549-53.