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ABSTRACT: The antioxidant effects of the essential oils from the fruit and leaves of Platycladus orientalis Franco (Cupressacae) were studied. Accordingly, their ability to inhibit (i) LDL oxidation, (ii) red blood cells hemolysis, (iii) insulin and hemoglobin glycosylation, and (iv) linoleic acid peroxidation were assessed. The results showed that (a) the antioxidant effect of the leaf oil was significantly higher than the fruit oil in all oxidative systems employed in the present investigation, except LDL oxidation, (b) a greater effect was observed in glycosylation system with more than 60% antioxidant properties, and (c) in linoleic acid peroxidation system, a greater antioxidant effect was observed after 2h incubation (about 45%).
Journal of Essential Oil Research 01/2011; 23:83-90. · 0.41 Impact Factor
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I Nasidze,
E Y S Ling,
D Quinque,
I Dupanloup,
R Cordaux,
S Rychkov,
O Naumova,
O Zhukova,
N Sarraf-Zadegan, G A Naderi,
S Asgary,
S Sardas,
D D Farhud,
T Sarkisian,
C Asadov,
A Kerimov,
M Stoneking
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ABSTRACT: We have analyzed mtDNA HVI sequences and Y chromosome haplogroups based on 11 binary markers in 371 individuals, from 11 populations in the Caucasus and the neighbouring countries of Turkey and Iran. Y chromosome haplogroup diversity in the Caucasus was almost as high as in Central Asia and the Near East, and significantly higher than in Europe. More than 27% of the variance in Y-haplogroups can be attributed to differences between populations, whereas mtDNA showed much lower heterogeneity between populations (less then 5%), suggesting a strong influence of patrilocal social structure. Several groups from the highland region of the Caucasus exhibited low diversity and high differentiation for either or both genetic systems, reflecting enhanced genetic drift in these small, isolated populations. Overall, the Caucasus groups showed greater similarity with West Asian than with European groups for both genetic systems, although this similarity was much more pronounced for the Y chromosome than for mtDNA, suggesting that male-mediated migrations from West Asia have influenced the genetic structure of Caucasus populations.
Annals of Human Genetics 06/2004; 68(Pt 3):205-21. · 2.57 Impact Factor
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ABSTRACT: The possible consequences of the long intermittent fasting schedule during Ramadan (one month of food and water intake limited to night hours, a practice that is followed by the majority of the Muslims worldwide) on certain biochemical constituents or coagulation variables have not been extensively documented.
During the month of Ramadan and two months after, we monitored the concentration of different plasma lipoproteins, lipoprotein (a) [Lp(a)], apoproteins A(1) and B, fibrinogen, factor VII activity and some selected hematological factors in 50 healthy subjects who were employees of institutes related to the Isfahan University of Medical Sciences and aged between 30 and 45 years. The effect of fasting in Ramadan on the relationship between biochemical and coagulation variables was also investigated.
The values of apoprotein B, Lp(a) and low-density lipoprotein cholesterol (LDL-C)/high-density lipoprotein cholesterol (HDL-C) ratio were significantly decreased during Ramadan (P<0.05), while total cholesterol (Tot-C), triglycerides (TG), LDL-C, HDL-C and fasting blood glucose did not change during that month. Among coagulation and hematological factors, fibrinogen level and factor VII activity were significantly decreased during the month (P<0.05). Results also indicated a significant positive association between fibrinogen level and Lp(a), factor VII activity and Tot-C, LDL-C, TG and Apo B during Ramadan.
Our findings contribute to a better understanding of previous reports, as the metabolic and coagulation changes that are considered as atherosclerosis risk factors are counterbalanced during Ramadan.
Annals of Saudi medicine 20(5-6):377-81. · 1.07 Impact Factor
