Liang-Yu Wang

Publications (3)2.15 Total impact

• Article: [Investigation on cataract surgery in Qingdao Eye Hospital].

  Li Meng, Li-Xin Xie, Jian Jiang, Liang-Yu Wang
  [show abstract] [hide abstract]
  ABSTRACT: To evaluate the cataract surgery status of Qingdao Eye Hospital and to explore the changes in living quality and people's awareness of the eye diseases in Qingdao based on this information. Various parameters from patients who underwent cataract surgery in Qingdao Eye Hospital in the years 1994, 1999 and 2004 were collected, including age, nuclear hardness, occupation, pre- and postoperative vision acuity as well as the type of surgical procedures and complications of the surgery. Data from different years were compared and analyzed to explore the changes and the significance of these changes. Three hundred and thirty-eight senile cataract cases were operated on in 1994 including 36 cases that underwent Phaco (10.65%). The percentage of nuclear hardness < IV, = IV and = V grade was 11.83%, 27.51% and 60.66% respectively. The age of the patient < 60 years, 60 - 69 years, 70 - 79 years and over 80 years was 12.34%, 33.14%, 33.43% and 21.01%, respectively. Four hundred and sixty senile cataract cases were operated on in 1999, including 180 cases that underwent Phaco (39.13%). The percentage of nuclear hardness < = III, = IV and = V grade was 24.35%, 38.26% and 37.39%, respectively. The age of the patient < 60 years, 60 - 69 years, 70 - 79 years and > 80 years was 14.13%, 35.22%, 31.96%, and 18.70%, respectively. Four hundred and ninety nine senile cataract cases were operated on in 2004 including 396 cases that underwent Phaco (79.36%). The percentage of nuclear hardness < IV, = IV and = V grade was 30.66%, 39.28% and 30.06%, respectively. The age of the patient < 60 years, 60 - 69 years, 70 - 79 years and > 80 years was 19.44%, 36.47%, 30.66% and 13.43%, respectively. The present study indicates that the number of cataract operations and the percentage of rural patients have increased gradually in the past 10 years in our hospital. The age of operated patients and nuclear hardness of the cataract, the percentage of hypermature cataract and severe vision-damaged cases have decreased gradually. The percentage of Phaco surgery has increased and the results of this operation have improved significantly. These changes indicate that economic conditions in Qingduo have developed, the life quality and health conditions of Qingdao's residents have improved rapidly. The people in this region have shown more and more concern for individual eye health.
  [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 10/2007; 43(10):897-901.
• Article: Real-time three-dimensional myocardial contrast echocardiography in assessment of myocardial perfusion defects.

  Li-xin Chen, Xin-fang Wang, Navin C Nanda, Andrew P Miller, Ming-xing Xie, Lei Zhuang, Ya Yang, Jing Wang, Run-qing Huang, Ying Yang, Hong-wen Fei, Liang-yu Wang
  [show abstract] [hide abstract]
  ABSTRACT: Both real-time three-dimensional echocardiography (RT3DE) and myocardial contrast echocardiography (MCE) are novel imaging techniques. The purpose of this study was to confirm the feasibility and accuracy of RT3DE combined with MCE for quantitative evaluation of myocardial perfusion defects. Thirteen dogs underwent ligation of the left anterior descending artery (LAD, n = 6) or distal branch of the left circumflex artery (LCX, n = 7) under general anaesthesia. Three to four ml of a perfluoropropane (C3F8) microbubble contrast agent was injected intravenously to assess the resulting myocardial perfusion defects with a commercially available Philips SONOS-7500 ultrasound system. After removal of the dog hearts, Evans blue dye was injected via the left and right coronary arteries to stain the myocardium at risk. In vitro anatomic measurements of myocardial mass after removal of the animals' hearts were used as controls. Left ventricular (LV) mass determined by RT3DE ranged 36.7 - 68.9 g [mean, (54.6 +/- 9.6) g] before coronary artery ligation, and correlated highly (r = 0.99) with in vitro measurement of LV mass [range, 38.9 - 71.1 g; mean, (55.6 +/- 9.3) g]. There was no significant difference between RT3DE and in vitro measurements of LV mass [range, 36.7 - 68.9 g; mean, (51.3 +/- 12.5) g. Or range, 38.9 - 71.1 g; mean, (53.7 +/- 12.3) g, respectively] and under-perfused mass [range, 0 - 21.4 g; mean, (12.0 +/- 6.9) g. Or range, 0 - 19.8 g; mean, (10.8 +/- 6.3) g, respectively] after the LAD ligation (P > 0.05). Likewise, no significant difference was present between RT3DE and in vitro measurements of LV mass [range, 50.1 - 65.4 g; mean, (57.5 +/- 5.9) g. Or range, 51.5 - 65.8 g; mean, (57.3 +/- 6.4) g, respectively] and under-perfused mass [range, 0 - 25.6 g; mean, (13.3 +/- 9.6) g. Or range, 0 - 22.7 g; mean, (12.8 +/- 8.1) g, respectively] after the LCX ligation (P > 0.05). For all the animals with coronary ligation, LV mass measured by RT3DE ranged 35.9 - 68.6 g [mean, (54.8 +/- 10.0) g] and there was no significant difference between RT3DE and in vitro measurements of LV mass and under-perfused mass (P > 0.05, r = 0.99). Further, the under-perfused mass derived from RT3DE [range, 0 - 25.6 g; mean, (12.7 +/- 8.2) g] correlated strongly with the in vitro measurements [range, 0 - 22.7 g; mean, (11.9 +/- 7.2) g] (r = 0.96). RT3DE with MCE is a rapid and accurate method for estimating LV myocardial mass and quantifying perfusion defects.
  Chinese medical journal 04/2004; 117(3):337-41. · 0.86 Impact Factor
• Source

  Available from: jcc.gr.jp

  Article: Experimental study of quantitative assessment of left ventricular mass with contrast enhanced real-time three-dimensional echocardiography.

  Lei Zhuang, Xin-Fang Wang, Ming-Xing Xie, Li-Xin Chen, Hong-Wen Fei, Ying Yang, Jing Wang, Run-Qing Huang, Ou-Di Chen, Liang-Yu Wang
  [show abstract] [hide abstract]
  ABSTRACT: To evaluate the feasibility and accuracy of measurement of left ventricular mass with intravenous contrast enhanced real-time three-dimensional (RT3D) echocardiography in the experimental setting. RT3D echocardiography was performed in 13 open-chest mongrel dogs before and after intravenous infusion of a perfluorocarbon contrast agent. Left ventricular myocardium volume was measured according to the apical four-plane method provided by TomTec 4D cardio-View RT1.0 software, then the left ventricular mass was calculated as the myocardial volume multiplied by the relative density of myocardium. Correlative analysis and paired t-test were performed between left ventricular mass obtained from RT3D echocardiography and the anatomic measurements. Anatomic measurement of total left ventricular mass was 55.6 +/- 9.3 g, whereas RT3D echocardiographic calculation of left ventricular mass before and after intravenous perfluorocarbon contrast agent was 57.5 +/- 11.4 and 55.5 +/- 9.3 g, respectively. A significant correlation was observed between the RT3D echocardiographic estimates of total left ventricular mass and the corresponding anatomic measurements (r = 0.95). A strong correlation was found between RT3D echocardiographic estimates of left ventricular mass with perfluorocarbon contrast and the anatomic results (r = 0.99). Analysis of intraobserver and interobserver variability showed strong indexes of agreement in the measurement of left ventricular mass with pre and post-contrast RT3D echocardiography. Measurements of left ventricular mass derived from RT3D echocardiography with and without intravenous contrast showed a significant correlation with the anatomic results. Contrast enhanced RT3D echocardiography permitted better visualization of the endocardial border, which would provide a more accurate and reliable means of determining left ventricular myocardial mass in the experimental setting.
  Journal of Cardiology 02/2004; 43(1):23-9. · 1.28 Impact Factor