Magdalena Jaworek

Jagiellonian University, Cracovia, Lesser Poland Voivodeship, Poland

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Publications (8)2.15 Total impact

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    ABSTRACT: Caudal regression syndrome (CRS) is a rare combination of congenital abnormalities characterized by caudal vertebral agenesis/dysgenesis that is usually associated with congenital anomalies of spinal cord, gastrointestinal and genitourinary organs. Although the exact teratogenic mechanism is not known, same environmental, e.g., hyperglycemia and genetic factors appears to play a crucial role in this fetopathy. Herein, we report an unusual case of CRS associated with unspecific white matter lesions and 18p-syndrome manifested by congenital ptosis, hypothyroidism, facial dysmorphy and chromosome 18p11.2 deletion.
    Brain and Development 05/2007; 29(3):164-6. · 1.67 Impact Factor
  • Anna Swierczyńska, Kłusek Renata, Magdalena Jaworek
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    ABSTRACT: Spasticity is a very bothering symptom, which aggravates disability and prevents in many cases a successful treatment. The aim of this paper was to remind different methods of treatment of spasticity, with a special attention to neurorehabilitation. In the research the complex pathogenesis of spasticity was referred, as well as factors influenced its aggravation and associated symptoms. Methods of evaluation of degree of spasticity were also recalled. The advantage and disadvantage of neurorehabilitation were also discussed. NDT-Bobath method as well as other kinesiotherapy methods were described with the necessity to make individualised program. The methods of rehabilitation which help in the reduction of muscle tone were refered, as well as the importance of botulin toxin, in the context of lack of efficacy of drugs in the reduction of spasticity, which cannot in fact help to reach better results of rehabilitation. The effectiveness of spasticity therapy with baclofen pump and other surgical methods were also mentioned. The decision to treat spasticity must be justified and depended on its intensity. It is necessary to develop new methods to obtain the durable effect of therapy of spasticity.
    Przegla̧d lekarski 02/2007; 64(11):974-7.
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    ABSTRACT: The paper presents the crucial role of video EEG, modern diagnostic method, which allowed synchronized recording of clinical status and EEG pattern of the patient. This method gives the possibility to compare these two parameters in term of paroxysmal events. Video EEG allows to diagnosed clinical events associated with bioelectrical discharges (epilepsy), recording of bioelectrical events without clinical seizures, diagnosing clinical attacks without bioelectrical discharges (pseudoseizures) and nonepileptic events (without epileptic character in video and EEG). This method is very useful especially in children and adolescents because of huge polymorphism of clinical signs, more common ambiguous diagnosis in this age and due to heterogeneity of bioelectrical brain function in children. Video EEG monitoring gives the possibility for clinical and electro-physiological interpretation of paroxysmal events and plays a crucial rule in localizing of epileptogenic focus, classification of the seizure, epilepsy type or syndrome. The role of suggestion and placebo is important in diagnosing psychogenic pseudoseizures. The duration of video EEG recording is differentiated and much more shorter in diagnosing the type of the event. Prolonged monitoring is needed in children with drag resistant epilepsy and in pre-operation evaluation.
    Przegla̧d lekarski 02/2006; 63(11):1224-9.
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    ABSTRACT: Epilepsy with polymorphic seizures is characterised by occurrence alternately two or more types of attacks. It represents a heterogenic group, taking into consideration etiology, course, management and prognosis, especially in the developmental age. The aim of this research was to establish a importance of epilepsy with polymorphic seizures in hospitalized with epilepsy children; the characteristics of type of epilepsy and epileptic syndrome, type of seizures, medication and results of pharmacological therapy were studied as well. 58 children with epilepsy with polymorphic seizures were included, out of 1225 children hospitalized with epilepsy between the years 1998 and 2004. The group consisted of 30 girls and 28 boys aged 2 weeks to 15. As diagnostic tools, neuroimaging using MRI and CT were performed. Other such as EEG and videoEEG, and also 10 types of examinations were done as well. Children with epilepsy and polymorfic seizures represented 4.8% of the group hospitalized with epilepsy. The majority of them were infants and children in the pre-school age. The most frequent causes of this type of epilepsy were early encephalopathies, and ceroidolipofuscinosis. Among 13 types of seizures, the most common in analysed cases were myoclonic jerks and tonic-clonic seizures. The most frequently used drugs were valproate and vigabatrin, rendering seizure-free 43% of children. Only in 1/3 of children the intellectual development was normal. The high frequency and heterogenity of epilepsy with polymorphic seizures confirms the opinion that this type of epilepsy constitute a significant issue in the epileptology of the developmental age. In most of the children epilepsy was associated with intellectual impairment, while final etiology of epilepsy in half of the children was not established. Therapy of epilepsy with polymorphic seizures was complicated and seizures were fully controlled in less than one half of the children.
    Przegla̧d lekarski 02/2005; 62(11):1244-8.
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    ABSTRACT: Spinal cord syndromes are caused by trauma in most cases, but the non traumatic spinal syndromes are needed to be urgently diagnosed and treated. It was to assess the prevalence of non traumatic spinal syndromes among hospitalized children with diseases of the nervous system and diagnostic analysis, therapy and its course. The group of 16 children age 0,5-18 years hospitalized in the years between 1996-2005 in the Department of Child Neurology in Krakow. The diagnosis was based on neurological assessment, imaging, cerebrospinal fluid examination and other data. Pharmacology, surgery and physiotherapy were performed as a treatment. The modified Rankin scale was used to assess the motor function after the spinal disorder. The non traumatic spinal syndromes were identified in 0.3% of hospitalized children. In 5 cases they were caused by infection etiology, in other 3 cases the congenital spinal cord malformations were diagnosed. Three children had spinal tumors, in a single case the haematoma, vertebral dislocation, the vertebral fracture with bulging of the annulus fibrosus of the intervertebral disc, isolated bulging and MRI hiperintensive lesion of unknown etiology were seen. Two patients, which were most motor impaired past away, the intramedular tumor caused the middle motor dysfunction, the others spinal syndromes elicted minor disability. The most common etiology of the non traumatic spinal syndromes, rare in hospitalized children, were inflammation, congenital spinal malformation and neoplastic tumors. Three fourths of the children had mild and other more severe handicaps due to non traumatic spinal syndromes.
    Przegla̧d lekarski 02/2005; 62(11):1281-6.
  • Marek Kaciński, Alicja Kubik, Magdalena Jaworek
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    ABSTRACT: Pseudo-epileptic seizures are a very crucial clinical problem in the developmental age and are coexisting with epileptic seizures in children. There is no answer to the question if the appearance of pseudoepileptic seizures in this age is connected to bioelectric brain function disorders. In adults with pseudoepileptic seizures the temporal area disorders are detected. The video EEG was performed in 36 girls and 4 boys aged 8 to 18 years (average 13 years). The most frequent types of pseudo seizure were syncope (30%), fainting (15%), abdominal pain (10%) and visual disturbances (10%). In 7.5% clonic and tonic-clonic seizures and in 2.5 % paroxysmal sense disorders were seen. Confusion of place and time and paroxysmal behavioral disorders in 5%. In 3 cases hyperventilation was observed. In 15/40 with pseudoseizures epilepsy was coexisting. In all children 1 hour interictal videoEEG monitoring was performed. The pattern was done during waking state and all children was activated. In 15, the procedure were repeated after sleep deprivation in physiological sleep. We analysed the basic activity, reactivity, symmetry and synchrony in the EEG patterns, presence of the epileptic-like grapho-elements and paroxysmal discharges. In sleep patterns the bioelectrical features, stages, epileptic-like and paroxysmal graphoelements are assessed. In 40% children with pseudoepileptic seizures, abnormalities of the interictal EEG were seen. Sleep deprivation provoked the abnormalities in another 4/15 children. In this pattern 27.5% children had localized paroxysmal discharges, and 22.5% generalized. In most of the cases the EEG was sensitive to stimulation. Pseudoepileptic seizures appear mostly in girls. One half of these cases had basic EEG pattern and paroxysmal bioelectric abnormalities, however 12/20 of them had epileptic seizures as well.
    Przegla̧d lekarski 02/2004; 61(11):1253-9.
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    ABSTRACT: Was to determine the influence of the persistent cavum of the septum pellucidum (CSP) on the children intellectual development in different age groups. THE MATERIAL AND METHODS: There were 53 children with CSP examined (3.4% of the hospitalised children), 28 girls and 25 boys aged 2 months-14 years. Among them 30 was with normal intellectual development, 14 children with IQ under the average and 9 with mental retardation. The control group consists of 30 children without CSP and with normal intellectual development. The children were divided into three groups: aged under 2 years, between 2 and 6 years and between 7 and 14 years. Using Psyche Cattell, Terman-Merrill and D. Wechsler (WISC-R) scales performed the general intellectual assessment. The evaluation of the cognitive, motor abilities and lateralization of the motor and visual functions in children was done using tests: Bender-Koppitz, Benton, R. Zazzo, M. Stambak, H. Spionek and Lingual Abilities Test. The anamnesis was obtained from parents. The statistic analyses was performed with chi-square and Fisher tests. The percentage of children with IQ under average and with mental retardation in the group <2 years was 60%, in 2-6 years 47% and in the group 7-14 years was 35%. The study show significantly lower score in the Code test of the D. Wechsler scale in children with CSP and normal intellectual development. Older children presented also significantly lower scores in manual abilities. A lot of intellectual functions were deleted in the majority of the children with CSP and the IQ under the average or with mental retardation. The CSP in children is connected to the deficits of the intellectual functions and that why the psychological assessment should be early performed in children with CSP.
    Przegla̧d lekarski 02/2004; 61(5):486-90.
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    ABSTRACT: The article presented the material of 12 children with vasculitis disorders and involvement of the nervous system, 8 of CNS and 4 of the peripheral nervous system. The most frequent form of these disorders was ischaemic stroke. Authors discussed issues specific for developmental diagnostic, etiopathogenetic and therapeutic topics.
    Neurologia i neurochirurgia polska 02/2004; 38(1 Suppl 1):S9-15. · 0.49 Impact Factor

Publication Stats

7 Citations
2.15 Total Impact Points

Institutions

  • 2007
    • Jagiellonian University
      Cracovia, Lesser Poland Voivodeship, Poland
  • 2004–2006
    • Collegium Medicum of the Jagiellonian University
      Cracovia, Lesser Poland Voivodeship, Poland