Włodzimierz Jerzy Musiał

Publications (3)1.82 Total impact

• Article: The influence of renal function and selected cardiovascular risk factors on the thickness of the intima-media complex in the peripheral arteries.

  Anna Lisowska, Włodzimierz Jerzy Musiał, Piotr Lisowski, Małgorzata Knapp, Jolanta Małyszko, Grazyna Latocha-Korecka, Hanna Bachórzewska-Gajewska
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  ABSTRACT: Background: Measurement of the intima-media thickness (IMT) in the peripheral arteries leads to better stratification of cardiovascular risk. This is of great importance in patients with chronic renal insufficiency, who are particularly vulnerable to developing atherosclerotic lesions. The aim of the study was to evaluate whether parameters of renal insufficiency and selected risk factors of atherosclerosis influence IMT in the peripheral arteries. Methods: The study population comprised 231 patients submitted to coronary angiography with ultrasonographic assessment of the common carotid artery (CCA), carotid artery bulb (CB) and common femoral artery (CFA) made contemporaneously with evaluation of IMT and atherosclerotic plaques. Renal function as well as selected clinical and biochemical risk factors of atherosclerosis were assessed. Two subgroups were analysed: 200 patients with coronary heart disease confirmed angiographically (study group) and 31 patients without coronary lesions (control group). Results: Significant negative correlation was found between glomerular filtration rate and IMT values in CCA (p < 0.001) as well as in CB (p < 0.05). Patients with abnormal glucose metabolism had significantly higher IMT values in CCA (0.95 +/- 0.30 vs. 0.87 +/- 0.20; p = 0.034). Hypercholesterolaemia did not influence the IMT values in CCA and CFA. There was no correlation between body mass index and IMT. Conclusions: Patients with chronic renal insufficiency presented higher values of IMT in CCA. The measurement of IMT appears to be a valuable non-invasive method of diagnosing preclinical stages of atherosclerosis in the described group of patients. (Cardiol J 2007; 14: 59-66).
  Cardiology journal 01/2007; 14(1):59-66. · 1.31 Impact Factor
• Article: [Cardiac myxoma attached to anterior leaflet--case report].

  Anna Lisowska, Małgorzata Knapp, Tomasz Hirnle, Włodzimierz Jerzy Musiał
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  ABSTRACT: Cardiac myxoma attached to anterior mitral leaflet - a case report. A case of a 64-year-old patient with a history of stroke and myocardial infarction is presented. Echocardiography revealed cardiac myxoma originating from anterior mitral leaflet. The patient underwent successful surgery. Differential diagnosis of cardiac myxoma is presented.
  Kardiologia polska 01/2005; 61(12):579-80. · 0.51 Impact Factor
• Article: [Is Q-wave on admission associated with microvascular injury in patients with acute myocardial infarction treated with primary angioplasty?].

  Sławomir Dobrzycki, Janusz Korecki, Marcin Kozuch, Karol Kamiński, Grazyna Latocha-Korecka, Bogusław Poniatowski, Piotr Filipczuk, Mariusz Mazur, Adam Gorlo, Włodzimierz Jerzy Musiał
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  ABSTRACT: Impaired microvascular flow, despite patent epicardial artery (no-reflow phenomenon), leads to greater left ventricular dysfunction after myocardial infarction (MI). Predictive factors associated with no-reflow remain largely unexplored. Q-wave on admission (Q(A)) is a sign of extensive ischemia probably predisposing to no-reflow. The aim of the study was to explore possible relation between Q(A) and electrocardiographic signs of no-reflow in patients with first MI. The study group was composed of 108 patients (81 men; mean age 60+/-11 years), with first ST-segment elevation MI, treated successfully with primary angioplasty (p-PTCA). ECG tracings were obtained before and 30 minutes after p-PTCA. The sum of ST-segment elevations (sum(ST(el))) in 3 contiguous leads with the highest ST(el) was calculated. Lack of 50% reduction of the sum(ST(el)) 30 minutes after angioplasty was defined as ECG sign of no-reflow. Presence of Q(A) was estimated in leads with ST(el). Q(A) was found in 42 (39%) patients. Q(A) was more often observed in patients with ECG signs of no-reflow (38% vs. 18%; p<0.05). Group with Q(A) showed larger damage of left ventricle estimated with ECG QRS score (7.7+/-4.4 vs. 6.1+/-3.4; p<0.05) as well as worse ejection fraction (42% vs. 46%; p=0.05). Patients with Q(A) have more often ECG signs of no-reflow than other patients with MI. Previously described worse function of left ventricle in this group, may be partially caused by more frequent no-reflow occurring in those patients. This fact suggests that adjunctive therapy preventing no-reflow could be beneficial in this group of patients.
  Przegla̧d lekarski 01/2004; 61(9):891-4.