Esther Roselló-Sastre

Publications (2)2.66 Total impact

• Article: Histologic retinacular changes associated with ischemia in painful patellofemoral malalignment.

  Vicente Sanchis-Alfonso, Esther Roselló-Sastre, Fernando Revert, Almudena García
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  ABSTRACT: Ischemic changes in 31 samples of lateral retinacula excised at surgical realignment in patients with isolated symptomatic patellofemoral malalignment resistant to conservative treatment were evaluated with conventional histology, electron microscopy, immunohistochemistry, and molecular biology. Morphologic and ultrastructural changes associated with ischemia including hypervascularization and increased vascular endothelial growth factor release were identified in painful patellofemoral malalignment. It is hypothesized that periodic short episodes of ischemia could be implicated in the pathogenesis of anterior knee pain in most cases of isolated symptomatic patellofemoral malalignment in active young patients by triggering neural proliferation.
  Orthopedics 07/2005; 28(6):593-9. · 2.66 Impact Factor
• Article: Anterior knee pain in the young patient--what causes the pain? "Neural model".

  Vicente Sanchis-Alfonso, Esther Roselló-Sastre
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  ABSTRACT: Anterior knee pain in young patients is the commonest type of knee disorder in clinical practice. However, the pathogenesis of this condition is unknown. On the basis of our recent research, we suggest a "neural model". In our view, hyperinnervation in the lateral retinaculum, mainly nociceptive substance P-positive nerves induced by the release of neural growth factor, is involved in the pathogenesis of anterior knee pain. We hypothesize that periodic short episodes of ischemia may trigger neural proliferation.
  Acta Orthopaedica Scandinavica 01/2004; 74(6):697-703.