Publications (2)1.65 Total impact
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Article: Refinements in the care and use of animals in toxicology studies-regulation, validation, and progress.
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ABSTRACT: During the past decade, important advances have been made in the humane care and use of laboratory animals used in toxicology studies, and there is strong international interest by the pharmaceutical sector in continuing with this progress. Because of the potential influence on human health, safety studies are highly regulated, and implementing refinements in laboratory animal care and use may require an initial validation study to demonstrate a lack of effect on study outcome. This paper provides an overview of issues surrounding implementation of animal care refinements in toxicology laboratory settings, including regulatory constraints, conducting validation studies, current progress in refinements, and areas for future consideration.Contemporary topics in laboratory animal science / American Association for Laboratory Animal Science 12/2003; 42(6):8-15. · 0.82 Impact Factor -
Article: Validation study of social housing of canines in toxicology studies.
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ABSTRACT: Optimal housing conditions for canines have evolved in light of changing research findings and animal welfare initiatives. Social housing of canines in toxicology studies was not considered standard housing in our facility. When the decision was made to explore social housing for toxicology studies in our facility, we noted a lack of published information. This study was performed to develop and validate social housing as an option for canines in toxicology studies. The potential impact to data gathered through toxicology studies in which the canines are socially housed is discussed.Contemporary topics in laboratory animal science / American Association for Laboratory Animal Science 03/2003; 42(2):29-30. · 0.82 Impact Factor
