Publications (3)6.56 Total impact
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Article: The use of Fourier-transform infrared spectroscopy for the quantitative determination of glucose concentration in whole blood.
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ABSTRACT: Fourier-transform infrared transmission spectroscopy has been used for the determination of glucose concentration in whole blood samples from 28 patients. A 4-vector partial least-squares calibration model, using the spectral range 950-1200 cm(-1), yielded a standard-error-of-prediction of 0.59 mM for an independent test set. For blood samples from a single patient, we found that the glucose concentration was proportional to the difference between the values of the second derivative spectrum at 1082 cm(-1) and 1093 cm(-1). This indicates that spectroscopy at these two specific wavenumbers alone could be used to determine the glucose concentration in blood plasma samples from a single patient, with a prediction error of 0.95 mM.Physics in Medicine and Biology 08/2003; 48(13):2023-32. · 2.83 Impact Factor -
Article: Determination of Glucose Concentration in Whole Blood using Fourier-Transform Infrared Spectroscopy.
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ABSTRACT: Fourier-transform infrared(FTIR) transmission spectroscopy has beenused for the determination of glucoseconcentrations in whole blood samples fromtwenty-eight patients. A four-vectorpartial least squares calibration model,using the spectral range 950-1200 cm(-1),yielded a standard error of prediction of0.59 mM for an independent test set. Forblood samples from a single patient, wefound that the glucose concentration wasproportional to the difference between thevalues of the second derivative spectrum at1082 cm(-1) and 1093 cm(-1), suggestingthat these two specific wavelengths can beused for determining glucose concentrationsin blood.Journal of Biological Physics 06/2003; 29(2-3):129-33. · 1.86 Impact Factor -
Article: Determination of Glucose Concentration in Whole Blood using Fourier-Transform Infrared Spectroscopy
[show abstract] [hide abstract]
ABSTRACT: Fourier-transform infrared(FTIR) transmission spectroscopy has beenused for the determination of glucoseconcentrations in whole blood samples fromtwenty-eight patients. A four-vectorpartial least squares calibration model,using the spectral range 950–1200 cm-1,yielded a standard error of prediction of0.59 mM for an independent test set. Forblood samples from a single patient, wefound that the glucose concentration wasproportional to the difference between thevalues of the second derivative spectrum at1082 cm-1 and 1093 cm-1, suggestingthat these two specific wavelengths can beused for determining glucose concentrationsin blood.Journal of Biological Physics 05/2003; 29(2):129-133. · 1.86 Impact Factor
Top Journals
Institutions
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2003
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University of Cambridge
- Department of Physics: Cavendish Laboratory
Cambridge, ENG, United Kingdom
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