T S Elsey

Publications (3)6.56 Total impact

• Source

  Available from: liv.ac.uk

  Article: The use of Fourier-transform infrared spectroscopy for the quantitative determination of glucose concentration in whole blood.

  Y C Shen, A G Davies, E H Linfleld, T S Elsey, P F Taday, D D Arnone
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  ABSTRACT: Fourier-transform infrared transmission spectroscopy has been used for the determination of glucose concentration in whole blood samples from 28 patients. A 4-vector partial least-squares calibration model, using the spectral range 950-1200 cm(-1), yielded a standard-error-of-prediction of 0.59 mM for an independent test set. For blood samples from a single patient, we found that the glucose concentration was proportional to the difference between the values of the second derivative spectrum at 1082 cm(-1) and 1093 cm(-1). This indicates that spectroscopy at these two specific wavenumbers alone could be used to determine the glucose concentration in blood plasma samples from a single patient, with a prediction error of 0.95 mM.
  Physics in Medicine and Biology 08/2003; 48(13):2023-32. · 2.83 Impact Factor
• Article: Determination of Glucose Concentration in Whole Blood using Fourier-Transform Infrared Spectroscopy.

  Y C Shen, A G Davies, E H Linfield, P F Taday, D D Arnone, T S Elsey
  [show abstract] [hide abstract]
  ABSTRACT: Fourier-transform infrared(FTIR) transmission spectroscopy has beenused for the determination of glucoseconcentrations in whole blood samples fromtwenty-eight patients. A four-vectorpartial least squares calibration model,using the spectral range 950-1200 cm(-1),yielded a standard error of prediction of0.59 mM for an independent test set. Forblood samples from a single patient, wefound that the glucose concentration wasproportional to the difference between thevalues of the second derivative spectrum at1082 cm(-1) and 1093 cm(-1), suggestingthat these two specific wavelengths can beused for determining glucose concentrationsin blood.
  Journal of Biological Physics 06/2003; 29(2-3):129-33. · 1.86 Impact Factor
• Source

  Available from: Yaochun Shen

  Article: Determination of Glucose Concentration in Whole Blood using Fourier-Transform Infrared Spectroscopy

  Y.C. Shen, A.G. Davies, E.H. Linfield, P.F. Taday, D.D. Arnone, T.S. Elsey
  [show abstract] [hide abstract]
  ABSTRACT: Fourier-transform infrared(FTIR) transmission spectroscopy has beenused for the determination of glucoseconcentrations in whole blood samples fromtwenty-eight patients. A four-vectorpartial least squares calibration model,using the spectral range 950–1200 cm-1,yielded a standard error of prediction of0.59 mM for an independent test set. Forblood samples from a single patient, wefound that the glucose concentration wasproportional to the difference between thevalues of the second derivative spectrum at1082 cm-1 and 1093 cm-1, suggestingthat these two specific wavelengths can beused for determining glucose concentrationsin blood.
  Journal of Biological Physics 05/2003; 29(2):129-133. · 1.86 Impact Factor