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Publications (2)1.81 Total impact

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    ABSTRACT: To determine the incidence of pregnancy among active injection-drug users and to identify factors associated with becoming pregnant. The Vancouver Injection Drug User Study (VIDUS) is a prospective cohort study that began in 1996. Women who had completed a baseline and at least one follow-up questionnaire between June 1996 and January 2002 were included in the study. Parametric and non-parametric methods were used to compare characteristics of women who reported pregnancy over the study period with those who did not over the same time period. A total of 104 women reported a primary pregnancy over the study period. The incidence of pregnancy over the follow-up period was 6.46 (95% confidence interval (CI) 5.24-7.87) per 100 person-years. The average age of women who reported pregnancy was younger than that of women who did not report pregnancy (27 vs. 32 years, p < 0.001). Women of Aboriginal ethnicity were more likely to report pregnancy (odds ratio 1.6, 95% CI 1.0-2.5). Comparison of drug use showed no significant differences in pregnancy rate with respect to the use of heroin, cocaine or crack (p > 0.05). In examining sexual behavior, women who reported having had a regular partner in the previous 6 months were three times more likely to have reported pregnancy. Despite the fact that 67% of women in this study reported using some form of contraception, the use of reliable birth control was low. Only 5% of women in our study reported the use of hormonal contraceptives. There were a high number of pregnancies among high-risk women in this cohort. This corresponded with very low uptake of reliable contraception. Innovative strategies to provide reproductive health services to at-risk women who are injecting drugs is a public health priority.
    The European Journal of Contraception and Reproductive Health Care 03/2003; 8(1):52-8. · 1.81 Impact Factor
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    ABSTRACT: Methods • Female participants in the Vancouver Injection Drug User Study (VIDUS) who had completed a baseline questionnaire between June 1996 and July 2001 were included. • Women who were older than 50 years at baseline or who reported having had a hysterectomy were excluded from this analysis. • The incidence of first pregnancy was calculated by the incidence density approach and is expressed in terms of person-years of observation. • Ninety-five percent confidence intervals around the incidence estimate were calculated based on the Poisson distribution. • To identify factors associated with incident pregnancy, a nested case-control design was used. Women who did not reported pregnancy for the duration of follow-up were frequency matched for the duration of follow-up with subjects who reported pregnancy. • Categorical variables were compared between groups using Pearson's chi-squared test.Continuous variables were compared using the Wilcoxon's rank-sum test. • Multivariate logistic regression analyses were used to identify independent factors associated with incident pregnancy.