Matt Brown

Publications (3)5.45 Total impact

• Article: Effects of threat context and cardiac sensitivity on fear responding to a 35% CO2 challenge: a test of the context-sensitivity panic vulnerability model.

  Michael J Telch, Jasper A J Smits, Matt Brown, Mandy Dement, Mark B Powers, Hanjoo Lee, Anushka Pai
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  ABSTRACT: The present study tested several predictions of a context-sensitivity panic vulnerability model emphasizing the interaction between threat context and threat sensitivities. Participants without a history of panic (N=47) completed both global and domain-specific panic relevant sensitivity measures and were then randomized to undergo a 35% CO2 inhalation challenge in the presence or absence of a cardiac defibrillator (threat context). As predicted by the model, cardiac sensitivity (but not trait anxiety or anxiety sensitivity) potentiated the effects of the presence of the defibrillator on CO2 fear responding. Moreover, as predicted by the model, the observed potentiation effects of cardiac sensitivity on CO2 fear responding were mediated by participants' threat appraisals connected to the presence of the defibrillator. Theoretical and clinical implications are discussed.
  Journal of behavior therapy and experimental psychiatry 12/2010; 41(4):365-72. · 2.48 Impact Factor
• Article: Differential sensitivity of the three ASI factors in predicting panic disorder patients' subjective and behavioral response to hyperventilation challenge.

  Matt Brown, Jasper A J Smits, Mark B Powers, Michael J Telch
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  ABSTRACT: The overall aim of the present investigation was to examine the association between the subscales of the ASI and emotional responding to voluntary hyperventilation challenge in a panic disorder population. Based on findings from [J. Abnorm. Psychol. 110 (2001) 372.], we predicted that the AS-Physical Concerns subscale would best predict the fear response to hyperventilation. We also examined the relative contribution of each of the three ASI subscales in predicting behavioral tolerance to hyperventilation. Participants (N = 192) meeting DSM-IV criteria for panic disorder with or without agoraphobia completed the Anxiety Sensitivity Index (ASI) and underwent a voluntary hyperventilation challenge. Consistent with prediction, the AS-Physical subscale significantly predicted subjective fear during the hyperventilation challenge (12% of variance accounted for); whereas only the AS-Social subscale accounted for significant variance (4%) in patients' behavioral tolerance to the hyperventilation challenge.
  Journal of Anxiety Disorders 02/2003; 17(5):583-91. · 2.96 Impact Factor
• Article: Effects of threat context and cardiac sensitivity on fear responding to a 35% CO2 challenge: A test of the context-sensitivity panic vulnerability model

  Michael J. Telch, Jasper A.J. Smits, Matt Brown, Mandy Dement, Mark B. Powers, Hanjoo Lee, Anushka Pai
  [show abstract] [hide abstract]
  ABSTRACT: The present study tested several predictions of a context-sensitivity panic vulnerability model emphasizing the interaction between threat context and threat sensitivities. Participants without a history of panic (N = 47) completed both global and domain-specific panic relevant sensitivity measures and were then randomized to undergo a 35% CO2 inhalation challenge in the presence or absence of a cardiac defibrillator (threat context). As predicted by the model, cardiac sensitivity (but not trait anxiety or anxiety sensitivity) potentiated the effects of the presence of the defibrillator on CO2 fear responding. Moreover, as predicted by the model, the observed potentiation effects of cardiac sensitivity on CO2 fear responding were mediated by participants’ threat appraisals connected to the presence of the defibrillator. Theoretical and clinical implications are discussed.
  Journal of Behavior Therapy and Experimental Psychiatry.