Hyoung Tae Kim

Korea University, Sŏul, Seoul, South Korea

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Publications (55)73.87 Total impact

  • Han Seo, Hyoung Tae Kim, Jae Eun Cha, In Cheol Bang
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    ABSTRACT: The moderator tank in a CANDU reactor plays a key role in the reactor core including the fuel channels and moderator. Understanding the circulation characteristics such as the flow pattern and temperature distribution in the moderator tank is important because the cooling capability is limited inside the fuel channels in the worst accident scenarios such as large break loss of coolant accident, resulting in heat removal through the Calandria tubes contacting with the fuels via thermal expansion. Therefore, measurement of the velocity profile and temperature distribution in the moderator tank is a key factor in the safety analysis of CANDU reactors because the moderator tank provides ultimate heat sink. In the present work, the velocity profile in a scaled CANDU6 moderator tank was obtained using particle image velocimetry from the 1st and 2nd jet orifices under symmetric and asymmetric flow conditions. The scaled moderator tank was prepared with acrylic, which is transparent to allow the laser penetration to create the light sheet for illuminating tracer particles. The velocity profile in the scaled moderator tank was obtained from the inlet nozzle running to the top of the tank along and near the curved wall surface and compared to a commercial CFD code, CFX.
    Annals of Nuclear Energy 11/2014; 73:361–372. · 0.80 Impact Factor
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    ABSTRACT: Abstract Bomarea, a member of the family Alstroemeriaceae, is distributed from Chile to Mexico and includes approximately 120 species. Recent molecular phylogenetic studies have clarified the monophyly of the family within the order Liliales and the sister relationship with the family Colchicaceae. At this time, five plastid genomes of Liliales have been analyzed at the familial level. To examine plastid genome variation at the generic level, we sequenced the plastid genome of Bomarea edulis, which is the most widely distributed species in the genus, and compared it with Alstroemeria aurea. The plastid genome sequence of B. edulis was 154,925 bp in length with a similar structure as A. aurea, excluding the IR-LSC junction. Ycf68 and infA were pseudogenes caused by frameshift mutations, and the ycf15 gene was deleted, similar to A. aurea.
    Mitochondrial DNA 10/2014; · 1.71 Impact Factor
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    Hyoung Tae Kim, Jung Sung Kim, Joo-Hwan Kim
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    ABSTRACT: Abstract The complete chloroplast (cp) genome sequence of Eustrephus latifolius was firstly determined in subfamily Lomandriodeae of family Asparagaceae. It was 159,736 bp and contained a large single copy region (82,403 bp) and a small single copy region (13,607 bp) which were separated by two inverted repeat regions (31,863 bp). In total, 132 genes were identified and they were consisted of 83 coding genes, 8 rRNA genes, 38 tRNA genes, 3 pseudogenes. rpl23 and clpP were pseudogenes due to sequence deletions. Among 23 genes containing introns, rps12 and ycf3 contained two introns and the rest had just one intron. The intact ycf68 was identified within an intron of trnI-GAU. The amino acid sequence was almost identical with Phoenix dactylifera in Aracales. Ycf1 of E. latifolius was completely located in IR. It was similar to cp genome structure of Lemna minor, Spirodela polyrhiza, Wolffiella lingulata, Wolffia australiana in Alismatales.
    Mitochondrial DNA 09/2014; · 1.71 Impact Factor
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    ABSTRACT: The CUPID code has been developed for a transient analysis of two-phase flows in nuclear reactor components. The primary objective of this study is to assess the applicability of the CUPID code to single- and two-phase flow analyses in the Calandria vessel of a CANDU nuclear reactor. At first, the CUPID code is validated against the Stern experiments, which were carried out to investigate the flow in a Calandria vessel. To represent the complicated internal structure of the Calandria vessel, a porous media approach is adopted for the tube bundle region of the Calandria vessel, and an open media approach is used for the outer region. Then, the two regions are modeled using a three-dimensional grid system with polyhedral meshes and bent-structured meshes, respectively. The calculation results of single-phase flow experiments showed good agreement with the experimental data. Thereafter, a hypothetical two-phase flow transient is simulated to assess the CUPID code applicability to two-phase flows analyses.
    Progress in Nuclear Energy 08/2014; 75:72–79. · 0.70 Impact Factor
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    ABSTRACT: To visualize the segment IV hepatic artery and to evaluate the variations in anatomy using multidetector computed tomography (MDCT) angiography.
    Clinical radiology. 06/2014;
  • Hyoung Tae Kim
    SNA + MC 2013 - Joint International Conference on Supercomputing in Nuclear Applications + Monte Carlo; 06/2014
  • Se-Myong Chang, Hyoung Tae Kim
    SNA + MC 2013 - Joint International Conference on Supercomputing in Nuclear Applications + Monte Carlo; 06/2014
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    Hyoung Tae Kim, Myong Gi Chung, Ki-Joong Kim
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    ABSTRACT: In this study, the chloroplast (cp) genome sequences from three early diverged leptosporangiate ferns were completed and analyzed in order to understand the evolution of the genome of the fern lineages. The complete cp genome sequence of Osmunda cinnamomea (Osmundales) was 142,812 base pairs (bp). The cp genome structure was similar to that of eusporangiate ferns. The gene/intron losses that frequently occurred in the cp genome of leptosporangiate ferns were not found in the cp genome of O. cinnamomea. In addition, putative RNA editing sites in the cp genome were rare in O. cinnamomea, even though the sites were frequently predicted to be present in leptosporangiate ferns. The complete cp genome sequence of Diplopterygium glaucum (Gleicheniales) was 151,007 bp and has a 9.7 kb inversion between the trnL-CAA and trnVGCA genes when compared to O. cinnamomea. Several repeated sequences were detected around the inversion break points. The complete cp genome sequence of Lygodium japonicum (Schizaeales) was 157,142 bp and a deletion of the rpoC1 intron was detected. This intron loss was shared by all of the studied species of the genus Lygodium. The GC contents and the effective numbers of codons (ENCs) in ferns varied significantly when compared to seed plants. The ENC values of the early diverged leptosporangiate ferns showed intermediate levels between eusporangiate and core leptosporangiate ferns. However, our phylogenetic tree based on all of the cp gene sequences clearly indicated that the cp genome similarity between O. cinnamomea (Osmundales) and eusporangiate ferns are symplesiomorphies, rather than synapomorphies Therefore, our data is in agreement with the view that Osmundales is a distinct early diverged lineage in the leptosporangiate ferns.
    Molecules and Cells 05/2014; · 2.21 Impact Factor
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    ABSTRACT: Hepatopulmonary syndrome (HPS) is a serious complication of end-stage liver disease, which is characterized by hypoxia, intrapulmonary vascular dilatation, and liver cirrhosis. Liver transplantation (LT) is the only curative treatment modality for patients with HPS. However, morbidity and mortality after LT, especially in cases of severe HPS, remain high. This case report describes a patient with typical findings of an extracardiac pulmonary arteriovenous shunt on contrast-enhanced transesophageal echocardiography (TEE), and clubbing fingers, who had complete correction of HPS by deceased donor LT. The patient was a 16-year-old female who was born with biliary atresia and underwent porto-enterostomy on the 55th day after birth. She had been suffered from progressive liver failure with dyspnea, clubbing fingers, and cyanosis. Preoperative arterial blood gas analysis revealed severe hypoxia (arterial O2 tension of 54.5 mmHg and O2 saturation of 84.2%). Contrast-enhanced TEE revealed an extracardiac right-to-left shunt, which suggested an intrapulmonary arteriovenous shunt. The patient recovered successfully after LT, not only with respect to physical parameters but also for pychosocial activity, including school performance, during the 30-month follow-up period.
    Clinical and molecular hepatology. 03/2014; 20(1):76-80.
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    ABSTRACT: The aim of this study was to evaluate the clinical course and angiographic changes of spontaneous isolated superior mesenteric artery dissection (SISMAD) after conservative treatment. Twenty-four patients with SISMAD admitted from September 2006 through March 2013 were included in this study. The clinical characteristics, type and location of the dissection, clinical outcome and angiographic changes were analyzed retrospectively. The median follow-up was 18.7 months (range 1.4-67.5 months). Eighteen patients (75 %) were symptomatic, and the median duration of abdominal pain was 2.5 days. All of the patients were treated conservatively. Follow-up computed tomography angiography showed complete remodeling in six patients (25 %), partial remodeling in four patients (17 %), no changes in nine patients (38 %), progression to total occlusion in four patients (17 %) and aneurysmal changes of the false lumen in one patient (4 %). Endovascular intervention was performed in the patient with aneurysmal changes. There was no mortality or morbidity related to the dissection. SISMAD represented variable angiographic changes, and its clinical course was benign in this study. For patients with SISMAD, if there is no evidence of bowel infarction, bleeding or aneurysmal changes, conservative treatment with close follow-up is sufficient and could reduce unnecessary endovascular interventions.
    Surgery Today 02/2014; · 0.96 Impact Factor
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    Hyoung Tae Kim, Ki-Joong Kim
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    ABSTRACT: Comparative analyses of complete chloroplast (cp) DNA sequences within a species may provide clues to understand the population dynamics and colonization histories of plant species. Equisetum arvense (Equisetaceae) is a widely distributed fern species in northeastern Asia, Europe, and North America. The complete cp DNA sequences from Asian and American E. arvense individuals were compared in this study. The Asian E. arvense cp genome was 583 bp shorter than that of the American E. arvense. In total, 159 indels were observed between two individuals, most of which were concentrated on the hypervariable trnY-trnE intergenic spacer (IGS) in the large single-copy (LSC) region of the cp genome. This IGS region held a series of 19 bp repeating units. The numbers of the 19 bp repeat unit were responsible for 78% of the total length difference between the two cp genomes. Furthermore, only other closely related species of Equisetum also show the hypervariable nature of the trnY-trnE IGS. By contrast, only a single indel was observed in the gene coding regions: the ycf1 gene showed 24 bp differences between the two continental individuals due to a single tandem-repeat indel. A total of 165 single-nucleotide polymorphisms (SNPs) were recorded between the two cp genomes. Of these, 52 SNPs (31.5%) were distributed in coding regions, 13 SNPs (7.9%) were in introns, and 100 SNPs (60.6%) were in intergenic spacers (IGS). The overall difference between the Asian and American E. arvense cp genomes was 0.12%. Despite the relatively high genetic diversity between Asian and American E. arvense, the two populations are recognized as a single species based on their high morphological similarity. This indicated that the two regional populations have been in morphological stasis.
    PLoS ONE 01/2014; 9(8):e103898. · 3.53 Impact Factor
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    ABSTRACT: We are planning to construct a scaled-down moderator test facility to simulate the CANDU-6 moderator circulation phenomena during steady state operation and accident conditions at the Korea Atomic Energy Research Institute. In the present work a preliminary experiment using a 1/40 scaled-down moderator tank has been performed to identify the potential problems of the flow visualization and measurement in the scaled-down moderator test facility. With a transparent moderator tank model, a flow field is visualized with a Particle Image Velocimetry (PIV) technique under an isothermal state, and the temperature field is measured using a Laser Induced Fluorescence (LIF) technique. A preliminary CFD analysis is also performed to find out the flow, thermal, and heating boundary conditions with which the various flow patterns expected in the prototype CANDU-6 moderator tank can be reproduced in the experiment.
    2013 21st International Conference on Nuclear Engineering; 07/2013
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    ABSTRACT: The purpose of this study was to evaluate the morphology of xiphoid process by dissection and using radiography of cadavers and multidetector computed tomography (MDCT) in patients. The xiphoid processes of 41 cadavers were dissected and taken by radiography. Other 902 patients examined by MDCT were revealed by image post-processing used with multiple planar reconstruction, maximum intensity projection and volume rendering. Xiphoid processes displayed pointed shape in 422 cases (44.75 %), oval shape in 387 cases (41.04 %), and forked shape in 134 cases (14.21 %). The sagittal shape of the xiphoid process was observed as ventrally deviated in 217 cases (23.01 %), dorsally deviated in 191 cases (20.25 %), S-shaped (ahead ventral, then dorsal) in 21 cases (2.23 %), and resembling a hook in 14 of ventral deviated patients and in 19 of those dorsal deviated patients. The foramen of xiphoid processes was found in 544 cases (57.69 %). The pattern L (a large foramen with a diameter of more than 5 mm) appeared in 302 cases (55.51 %), pattern S (a small foramen with a diameter of no more than 5 mm) in 155 cases (28.49 %), pattern LS (a mixture of a large and a small foramina) in 37 cases (6.80 %), and pattern SS (two or more small foramina) in 50 cases (9.19 %). Human xiphoid process appeared in morphological diversity. The anatomic structure and ossification degree of xiphoid process was well evaluated by MDCT. Our data may be used for diagnosis and surgical treatment of xiphoid process-related diseases.
    Anatomia Clinica 07/2013; · 0.93 Impact Factor
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    ABSTRACT: We present a rare variation of the right-sided aortic arch with the retroesophageal left subclavian artery as the forth branch found in a cadaver of an 89-year-old Korean woman during a routine dissection. In this case, the first branch that arose from the ascending aorta was the left common carotid artery, which crossed ventral to the trachea in a left cephalic direction, followed by the right common carotid artery and then the right subclavian artery. Distal to these branches the aortic arch ran dorsally, passing between the esophagus and the vertebra. The left subclavian artery arose from the descending portion of the aortic arch, crossing over to the left upper extremity behind the esophagus. This anomaly was not accompanied by congenital heart disease. Accurate information regarding this variation is of great importance to surgeons for its early identification and preservation during interventions and to radiologists for precise interpretation of angiograms.
    Anatomy & cell biology 06/2013; 46(2):167-70.
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    ABSTRACT: Living-donor liver transplant for a big hepatocellular carcinoma located in the caudate lobe is challenging owing to dissemination of cancer cells during recipient hepatectomy. We report a case of living-donor liver transplant using the right side of the liver of a living donor combined with inferior vena cava interposition graft after en bloc resection of the liver and retrohepatic inferior vena cava for hepatocellular carcinoma in the caudate lobe. A 50-year-old man with chronic hepatitis B cirrhosis developed hepatocellular carcinoma in the caudate lobe and segment 5. The diameters of the masses were 4.5 cm and 2.5 cm. His model for end-stage liver disease score was 17, and he had a moderate amount of ascites. For the recipient hepatectomy, en bloc resection of the entire liver, including retrohepatic inferior vena cava and reconstruction of inferior vena cava with Dacron graft, were performed. We then performed a transplant of the right lobe taken from the living donor. This technique can be a new alternative curative treatment option for hepatocellular carcinoma located on the hepatocaval confluence or close to the inferior vena cava. We should evaluate the long-term safety for cancer recurrence and infection of an artificial vascular graft in the milieu of immunosuppression after liver transplant.
    Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation. 11/2012;
  • Hyoung Tae Kim
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    ABSTRACT: The open calculations of two Small Break Loss of Coolant Accident (SBLOCA) experiments in the RD-14M integral test facility are performed as an International Atomic Energy Agency (IAEA) activity of International Collaborative Standard Problem (ICSP) with the objective to benchmark and validate the thermal–hydraulic analysis code against qualified data for Heavy Water Reactor (HWR) systems. This ICSP started with the first meeting of the participants in Vienna in 2007 November. Two tests were selected for this activity, test B9006, a 7-mm inlet header break experiment with pressurized accumulator emergency coolant injection, performed in 1990, and test B9802, a 3-mm inlet header break experiment, performed in 1998, to provide data with full channel power to study boiling in the channels and condensation in the steam generators. The previously performed blind simulations demonstrated that the CATHENA code is capable of adequately predicting the primary pressure depressurization, channel flow rate, channel voiding for tests B9006 and B9802, and the high pressure core injection flow by CATHENA accumulator model and switching time from high pressure to low pressure injections for test B9006. However, several significant discrepancies between the code predictions and the measurement data were noted, and attributed to the input errors and the code models relevant to post-dryout (PDO) heat transfer phenomena in the heated channels of test B9802. Therefore, the open calculations are performed to allow correction of previous blind calculations in the present study. These open calculations include the Senaratne and Leung model with the optimized coefficients of its correlation for the test B9802, which can predict more accurately the onset of sustained dryout on the surface of the heater rods. The improvement of the open calculation results are shown by comparing them with the test data and also with the blind calculation results.
    Annals of Nuclear Energy 08/2012; 46:63–75. · 0.80 Impact Factor
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    ABSTRACT: In this study, a thermal hydraulic behavior of the moderator in the CANDU reactor was numerically investigated by using CUPID code. KAERI has been developing a component-scale thermal hydraulics code, CUPID. The aim of the code is multi-dimensional, multi-physics and multi-scale thermal hydraulics analysis. This code adopts a three-dimensional, transient, two-phase and three-field model, and includes physical models and correlations of the interfacial mass, momentum, and energy transfer for the closure. To avoid the complexity to generate computational geometry around the matrix of 440 Calandria tubes, a porous media approach was applied. Flow resistance inside the porous media zone was derived from the empirical correlation of the frictional pressure loss. In order to consider the turbulent jet inflows from the inlet nozzles, the standard k-ε turbulence model was applied. For the grid dependency test, three different grid systems were tested. The moderator test vessel at Stern Laboratories Inc. (SLI) for the validation is a cylinder with a diameter of 2m and a length of 0.2m (a thin “slice” of CANDU-6 Calandria vessel). Since the axial flow is assumed to be invariant, two-dimensional calculation was performed. Vertical profile of the liquid temperature was compared with other calculation results as well as experimental data.
    2012 20th International Conference on Nuclear Engineering and the ASME 2012 Power Conference; 07/2012
  • Seung Won Lee, Hyoung Tae Kim, In Cheol Bang
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    ABSTRACT: The fuel rod performance of enhanced thermal conductivity UO2/graphene composites is investigated through a LBLOCA analysis. The benefits increased monotonically with increasing thermal conductivity in terms of reduced fuel center temperature and PCT. The performance of the UO2/graphene composite fuel is assessed in OPR-1000 (Optimized Power Reactor-1000) during a LBLOCA. Graphene can be a promising material for developing advanced nuclear fuel because of its property about the high thermal conductivity and low absorption cross section. The results confirm a LBLOCA performance related to PCT of the UO2/graphene composite fuel and its potential while maintaining large safety margins.
    2012 20th International Conference on Nuclear Engineering and the ASME 2012 Power Conference; 07/2012
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    ABSTRACT: BACKGROUND: We investigated the effect of Anemarrhena asphodeloides Bunge (Liliaceae) water extract (AAWE) on mast cell-mediated anaphylactic reactions. Mast cell-mediated anaphylactic reaction is involved in many allergic diseases, including asthma and allergic rhinitis. In Korea, where it has been used as a traditional medicine, AAWE is known to have antioxidant and anticancer activity. However, its specific effect on mast cell-mediated anaphylactic reactions is still unknown. METHODS: We examined whether or not AAWE could inhibit IgE-mediated passive cutaneous anaphylaxis (PCA), compound 48/80-induced systemic anaphylaxis, and mast cell activation. RESULTS: Oral administration of AAWE inhibited compound 48/80-induced systemic anaphylaxis in mice. AAWE also inhibited the local allergic reaction, PCA, activated by anti-dinitrophenyl IgE antibody in rats. AAWE reduced compound 48/80-induced degranulation of rat peritoneal mast cells (RPMCs). Moreover, AAWE inhibited histamine release and calcium uptake of RPMCs induced by compound 48/80 in a dose-dependent manner. AAWE also significantly inhibited secretion of tumor necrosis factor-α, interleukin (IL)-1β, and IL-6 in phorbol 12-myristate 13-acetate plus calcium ionophores A23187-stimulated RPMCs. CONCLUSIONS: These results suggest that AAWE suppresses compound 48/80-induced mast cell activation by inhibition of cellular mechanisms in signaling pathways, and would be beneficial for treatment of mast cell-mediated anaphylactic response.
    Experimental and toxicologic pathology: official journal of the Gesellschaft fur Toxikologische Pathologie 01/2012; · 1.43 Impact Factor
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    ABSTRACT: A transient, three-dimensional, two-phase flow analysis code, CUPID, has been developed in KAERI. In this work, we performed a preliminary analysis using the CUPID code to investigate the thermal-hydraulic behavior of the moderator in the Calandria vessel of a CANDU reactor. At first, we validated the CUPID code using the three experiments that were performed at Stern Laboratories Inc. To avoid the complexity to generate computational mesh around the Calandria tube bundles, a porous media approach was applied for the region. The pressure drop in the porous media zone was modeled by an empirical correlation. The results of the calculations showed that the CUPID code can predict the mixed flow pattern of forced and natural convection inside the Calandria vessel very well. Thereafter, the analysis was extended to a two-phase flow condition. Also, the local maximum temperature in the Calandria vessel was plotted as a function of the injection flow rate, which may be utilized to predict the local subcooling margin.
    Journal of Energy Engineering. 01/2012; 21(4).

Publication Stats

245 Citations
73.87 Total Impact Points

Institutions

  • 2014
    • Korea University
      • Department of Life Sciences
      Sŏul, Seoul, South Korea
    • Gachon University
      • Department of Life Science
      Sŏngnam, Gyeonggi Province, South Korea
  • 2008–2014
    • Chonbuk National University Hospital
      Sŏul, Seoul, South Korea
  • 2002–2014
    • Korea Atomic Energy Research Institute (KAERI)
      Daiden, Daejeon, South Korea
    • Korea Advanced Institute of Science and Technology
      • Department of Nuclear and Quantum Engineering
      Seoul, Seoul, South Korea
  • 2005–2013
    • Chonbuk National University
      • School of Medicine
      Sŏul, Seoul, South Korea
  • 2009
    • Kyungpook National University Hospital
      Sŏul, Seoul, South Korea
  • 2006–2009
    • Keimyung University
      • Dongsan Medical Center
      Sŏul, Seoul, South Korea
    • Chungnam National University
      Daiden, Daejeon, South Korea
  • 2007
    • Kyungpook National University
      • Department of Microbiology
      Daikyū, Daegu, South Korea