Xiaoguang Yu

Publications (2)0 Total impact

• Article: [Comparison of total hip replacement and transplantation of vascularized bone graft in treating late ischemic necrosis of the femoral head].

  Dewei Zhao, Yao Zhang, Weiming Wang, Jianmin Lu, Kemin Zhang, Xiaoguang Yu, Qiang Sun
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  ABSTRACT: To compare the effects and indications of total hip replacement (THR) and transplantation of vascularized bone graft in treating late ischemic necrosis of the femoral head. From March 1986 to March 1993, 81 patients with late ischemic necrosis underwent treatment. Of 81 patients, 59 patients who suffered in unilateral hip were divided into 2 groups: 26 underwent total hip replacement and 33 underwent transplantation of vascularized bone graft. There was no significant difference in the Harris-scores of the two groups before operations (P>0.05). The Harris hip scores were compared between different ages (<30 years, 31-50 years, and >51 years) in two groups. The follow-up ranged from 10 years and 3 months to 16 years and 5 months (15 years and two months on average). The changes of Harris-scores of the two groups after operations had significant difference in initial stage (P<0. 05), but had no significant difference in the long term (P>0.05). The change of Harris-scores of patients who underwent total hip replacement had no significant difference between different ages (P>0.05), but that of patients who underwent transplantation of vascularized bone graft had significant difference between different ages (P<0.05). Both groups had satisfactory effects in treating late ischemic necrosis of the femoral head. Both methods are effective in treating late ischemic necrosis of the femoral head. Total hip replacement can be more effective in senior patients. Transplantation of vascularized bone can be more effective in young patients.
  Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 09/2005; 19(9):700-2.
• Article: [Protection effect of nerve implantation after peripheral nerve injury to rats].

  Dewei Zhao, Weiming Wang, Kaifu Kang, Tuo Jing, Tienan Wang, Xiaoguang Yu, Lei Yang, Xu Cui
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  ABSTRACT: To investigate the protection effect of nerve implantation to the neurons after sciatic nerve injury to adult rats. Thirty male Sprague-Dawley rats weighing 180 - 220 g (8 - 9 weeks of age) were randomly divided into four groups. Group A consisted of normal rats without operation. In group B, the sciatic nerve of rats was transected, with the proximal stump of the sciatic nerve ligated to inhibit nerve regeneration. In group C, a sciatic nerve crushed model was set up. In group D, a sciatic nerve implantation model was established. The rats were sacrificed on postoperative days 7, 14 and 28 respectively. The L(4)-L(6) segments of the spinal cord were harvested. TUNEL technique was used to detect apoptotic motor neurons. HE and Toluidine Blue staining was used for counting motor neurons. The apoptotic neurons detected on the 28th postoperative day were significantly fewer in the implantation group than in the other groups (P < 0.05). The number of motor neurons was significantly higher in the implantation group than in other two control groups (P < 0.05). Nerve implantation exerts protective effect on neurons after nerve injury.
  Zhonghua wai ke za zhi [Chinese journal of surgery] 12/2002; 40(11):862-4.