Hironori Ohuchi

Publications (2)9 Total impact

• Article: Occurrence of norovirus infections unrelated to norovirus outbreaks in an asymptomatic food handler population.

  Tamaki Okabayashi, Shin-ichi Yokota, Yasuo Ohkoshi, Hironori Ohuchi, Yasuhiro Yoshida, Masayuki Kikuchi, Koichi Yano, Nobuhiro Fujii
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  ABSTRACT: Norovirus (NV) is the most common causative agent of nonbacterial gastroenteritis. Reports of surveillance of NV in facilities that reported outbreaks are frequently found in publications, but reports of that in facilities without outbreaks are not found. We investigated the molecular epidemiology of NV isolates derived from asymptomatic food handlers working at a non-outbreak food catering facility in Hokkaido, Japan, from February to March in 2005 and January to February in 2006 by RNA polymerase gene sequencing. Approximately 12% (20/159) of the samples were positive for genogroup II (GII; 10.1% in 2005 and 14.2% in 2006). The GI genotypes were not detected. The data from the phylogenetic analysis indicated that, among the 20 strains detected, 13 strains were GII/genotype 2 (GII/2), two were GII/3, three were GII/8, and two were GII/12. GII/4, which has been found most frequently in recent outbreaks worldwide, including Japan, was not detected. We found that one individual was coinfected with two genotypes, GII/2 and GII/12. This is the first report of the detection of NV genotypes in asymptomatic food handlers working at a non-outbreak facility. The excretion of NV from healthy individuals may be an infection source of NV outbreaks as well as other food-borne diseases.
  Journal of clinical microbiology 07/2008; 46(6):1985-8. · 4.16 Impact Factor
• Source

  Available from: ncbi.nlm.nih.gov

  Article: Fluoroquinolone-resistant Streptococcus pneumoniae strains occur frequently in elderly patients in Japan.

  Shin-Ichi Yokota, Kiyoshi Sato, Osamu Kuwahara, Satoshi Habadera, Naoyuki Tsukamoto, Hironori Ohuchi, Hirotsugu Akizawa, Tetsuo Himi, Nobuhiro Fujii
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  ABSTRACT: We identified and genetically characterized seven fluoroquinolone-resistant Streptococcus pneumoniae strains among 293 clinical strains isolated from 1999 to 2001 in Japan. The resistant strains were isolated only from adults, and 7 of 31 isolates (22.6%) were from patients more than 20 years old. Resistant strains were not found in 262 isolates from children under age 10.
  Antimicrobial Agents and Chemotherapy 11/2002; 46(10):3311-5. · 4.84 Impact Factor