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ABSTRACT: The purpose of the study was to understand and describe the hospital workers' experience related to the hospital evaluation program implemented in Korea between 2004 and 2009.
During 2010, data were collected using focus group interviews. Four focus group interviews were held with a total of 28 hospital workers participating. All interviews were recorded and transcribed as they were spoken, and data were analyzed using qualitative content analysis.
Nine themes emerged from the analysis: 1) Positive change in the necessity of the evaluation; 2) Improvement in the hospital system, facilities, and human resources; 3) Unity through cooperation among departments; 4) Nursing work overload; 5) Lack of physicians' awareness and responsibilities; 6) Unfair and unrealistic evaluation items; 7) Lack of credibility of the outcome; 8) Shifting responsibility for negative outcomes to the workers; 9) Lack of pragmatic utility.
The results of the study demonstrate that the hospital evaluation program played a key role in improving some work environments and communication among departments. At the same time, they show various negative themes resulting from the context of very authoritarian hospital systems and a connection-oriented society in Korea.
Journal of Korean Academy of Nursing 08/2011; 41(4):568-79. · 0.35 Impact Factor
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ABSTRACT: Peripheral exudative hemorrhagic chorioretinopathy (PEHCR) is a rare condition characterized by either subretinal exudates or subretinal hemorrhage outside the macula. The objective of this case report is to describe PEHCR lesions in Korean patients.
Five eyes of four patients are reviewed.
All cases were characterized by either peripheral subretinal exudates or hemorrhage with age-related degeneration. Four of the lesions appeared as subretinal masses, and the other manifested as a large retinal pigment epithelial alteration combined with subretinal exudates and subretinal fibrosis. Two of the patients evidenced serious visual impairment induced by massive subretinal hemorrhage extending to the fovea. Visual acuity in the other three eyes studied remained stable.
PEHCR appears to be a variant of age-related macular degeneration that occurs in Asians. Although PEHCR is known to be self-limiting, it frequently causes subfoveal extensions of subretinal blood and fluid.
Japanese Journal of Ophthalmology 05/2010; 54(3):227-31. · 0.92 Impact Factor
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ABSTRACT: Shwachman-Diamond syndrome (SDS) is an autosomal recessive genetic disorder, consisting of exocrine pancreatic insufficiency, chronic neutropenia, neutrophil chemotaxis defects, metaphyseal dysostosis, short stature, dental caries, and multiple organ involvements. Although SDS is the second most common hereditary abnormality of exocrine pancreas following cystic fibrosis in the Western countries, it has rarely been reported in Asia. We diagnosed a case of SDS in a 42-month-old girl, and genetic analysis including the relatives of the patient confirmed the diagnosis for the first time in Korea. She had short stature, steatorrhea, dental caries, and recurrent prulent otitis media and pneumonias. Laboratory studies revealed cyclic neutropenia, and serum levels of trypsin, amylase, and lipase were decreased. Simple radiography revealed metaphyseal sclerotic changes at the distal femur. A CT scan demonstrated a fatty infiltration and atrophy of the pancreas. On direct sequencing analysis of Shwachman-Bodian-Diamond Syndrome gene exon 2 region, the patient was homozygous for the c.258+2T>C mutation and heterozygous for the c.183_184TA>CT mutation and c.201A>G single nucleotide polymorphism. Treatment with pancreatic enzyme replacement, multivitamin supplementation, and regular to high fat diet improved her weight gain and steatorrhea.
Journal of Korean Medical Science 03/2008; 23(1):142-5. · 0.99 Impact Factor
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ABSTRACT: The first enantioselective synthesis of (+)-hygrine (1) is reported. 1 was obtained in 12 steps with 29% overall yield and 97% ee via asymmetric phase-transfer catalytic alkylation and ring-closing metathesis as key steps. The absolute configuration of (+)-hygrine could be directly confirmed as R.
The Journal of Organic Chemistry 09/2006; 71(17):6690-2. · 4.45 Impact Factor
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ABSTRACT: To report a case of bilateral bullous exudative retinal detachment in central serous chorioretinopathy (CSC) which was attached by vitrectomy and internal drainage of the subretinal fluid.
A 47-year-old man affected by bilateral atypical CSC with a bullous retinal detachment with subretinal exudate. A fluorescein angiogram (FAG) showed multiple points of leakage and staining of subretinal fibrosis. A tentative diagnosis of Vogt-Koyanagi-Harada (VKH) syndrome was made and the patient was treated with systemic corticosteroids and immunosuppressive agents. However, the subretinal fluid was not absorbed. He was then treated with vitrectomy and internal drainage of subretinal fluid.
The retina was attached successfully in both eyes. Visual acuity improved to 20/50 in his left eye but did not improve in the right eye due to subretinal fibrotic scarring and atropic changes on the macula.
Our case suggests that the surgical management of bullous exudative retinal detachment is safe and necessary.
Korean Journal of Ophthalmology 07/2006; 20(2):131-8.
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Eun-Ja Chung,
Hyun-Ja Kim,
Kwang-Hee Park,
Young-Ae Song,
Boek-Nam Lee,
Mi-Jeong Lee, Jeong-Hee Lee,
Hye-A Lee,
Yeon-Sook Lim,
Eun-Young Choi,
Hye-Young Hwang,
Hyun-Sook Lee
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ABSTRACT: This study was designed to analyze the time for direct and indirect nursing activity to evaluate the workload of nurses using a full Electronic Medical Record (EMR) system on practice. The result is that the mean time for nursing activity per nurse was 499.56 minutes, the mean time for direct nursing activity per nurse was 251.1 minutes (50.3%), and the mean time for indirect nursing activity per nurse was 248.42 minutes(49.7%). The time for direct nursing activity was more than the time for indirect nursing activity. There was a significant difference in the time for nursing activity according to workplace (p < 0.00*), but no difference according to nursing career. Regarding 3 duty-shifts, the time for direct nursing activity was highest in the evening shift and the time for indirect nursing activity was highest in the night shift.
Studies in health technology and informatics 02/2006; 122:499-502.
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ABSTRACT: [reaction: see text]. Highly enantioselective synthesis of a potent metabotropic receptor ligand, (2S)-alpha-(hydroxymethyl)-glutamic acid (2, HMG) was accomplished by the catalytic Michael addition of 2-naphthalen-1-yl-2-oxazoline-4-carboxylic acid tert-butyl ester (3b), using the phosphazene base, BEMP, in CH(2)Cl(2) at -60 degrees C in the presence of (S)-binaphthyl quaternary ammonium salt 4.
Organic Letters 08/2005; 7(15):3207-9. · 5.86 Impact Factor
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Jihye Lee,
Yeon-Im Lee,
Myoung Joo Kang,
Yeon-Ju Lee,
Byeong-Seon Jeong, Jeong-Hee Lee,
Mi-Jeong Kim,
Ji-yeon Choi,
Jin-Mo Ku,
Hyeung-geun Park,
Sang-sup Jew
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ABSTRACT: [reaction: see text] An enantioselective synthetic method for alpha-alkylserines by the phase-transfer catalytic alkylation of 2-phenyl-2-oxazoline-4-carbonylcamphorsultam (4a) was developed. The phase-transfer catalytic alpha-alkylation of 4a using P2-Et at -78 degrees C gave alpha-alkylation (75 to approximately 99%, 90 to approximately 97% de), which could be easily hydrolyzed to alpha-alkylserines.
The Journal of Organic Chemistry 06/2005; 70(10):4158-61. · 4.45 Impact Factor
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Hyeung-geun Park,
Mi-Jeong Kim,
Mi-Kyung Park,
Hyun-Ju Jung,
Jihye Lee,
Sea-hoon Choi,
Yeon-Ju Lee,
Byeong-Seon Jeong, Jeong-Hee Lee,
Mi-Sook Yoo,
Jin-Mo Ku,
Sang-sup Jew
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ABSTRACT: A new Merrifield-resin-derived glycinimine tert-butyl ester (9) was prepared and applied to the enantioselective synthesis of non-natural alpha-amino acids. High enantioselectivities (86 to >99% ee) were accomplished by employing the aldimine linker under phase-transfer alkylation conditions, using 50% aqueous CsOH in toluene/chloroform (7:3) at 0 degrees C in the presence of N-(9-anthracenylmethyl)-O(9)-allylcinchonidium bromide (10 mol %).
The Journal of Organic Chemistry 04/2005; 70(5):1904-6. · 4.45 Impact Factor
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Sang-Sup Jew, Jeong-Hee Lee,
Byeong-Seon Jeong,
Mi-Sook Yoo,
Mi-Jeong Kim,
Yeon-Ju Lee,
Jihye Lee,
Sea-Hoon Choi,
Kyungjae Lee,
Myoung Soo Lah,
Hyeung-Geun Park
Angewandte Chemie International Edition 03/2005; 44(9):1383-5. · 13.45 Impact Factor
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ABSTRACT: [structure: see text] The Cinchona alkaloid-derived quaternary ammonium salts containing 2'-N-oxypyridine and 2'-cyanobenzene moieties were prepared and evaluated as phase-transfer catalysts in the enantioselective alkylation of glycine imine ester 1. The N-oxypyridine and cyanobenzene moieties might play an important role to form a rigid conformation by coordinating with H(2)O via hydrogen bonding leading to high enantioselectivity (97 approximately >99% ee), which provides evidence of an electronic factor for the high enantioselective catalytic efficiency in phase-transfer alkylation.
Organic Letters 03/2005; 7(6):1129-31. · 5.86 Impact Factor
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ABSTRACT: Although there have been a few reported cases of Enterococcal endophthalmitis, this is an unusual case of endophthalmitis complicated with corneal ulcer caused by Enterococcus faecalis. A 67-year-old male patient with diabetes mellitus underwent secondary intraocular lens implantation. Post-operative recovery was uneventful until a wound rupture was noted 3 weeks after the operation. On day 12 after the repair of the wound, endophthalmitis accompanied by wound necrosis and a full-thickness corneal ulcer was detected. His vision was light perception, and Enterococcus faecalis was identified by culture in samples of conjunctival sac, anterior chamber and vitreous humor. After 3 rounds of intravitreal antibiotics injection, the vitreous opacity disappeared on ultrasonographic finding but corneal opacity and corneal neovascularization still remained.
Korean Journal of Ophthalmology 01/2005; 18(2):175-9.
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Sang-Sup Jew,
Yeon-Ju Lee,
Jihye Lee,
Myoung Joo Kang,
Byeong-Seon Jeong, Jeong-Hee Lee,
Mi-Sook Yoo,
Mi-Jeong Kim,
Sea-Hoon Choi,
Jin-Mo Ku,
Hyeung-Geun Park
Angewandte Chemie International Edition 05/2004; 43(18):2382-5. · 13.45 Impact Factor
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ABSTRACT: Systematic investigations to develop an efficient enantioselective synthetic method for alpha-alkyl-alanine by catalytic phase-transfer alkylation were performed. The alkylation of 2-naphthyl aldimine tert-butyl ester, 1E, with RbOH and O(9)-allyl-N-2',3',4'-trifluorobenzylhydrocinchonidinium bromide, 6, at -35 degrees C showed the highest enantioselectivities, up to 96% ee.
The Journal of Organic Chemistry 06/2003; 68(11):4514-6. · 4.45 Impact Factor
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Angewandte Chemie International Edition 09/2002; 41(16):3036-8. · 13.45 Impact Factor
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Tetrahedron. 60(19):4243-4249.
