Jason A Miller

Publications (5)39.63 Total impact

• Article: Axial ligand effects: utilization of chiral sulfoxide additives for the induction of asymmetry in (salen)ruthenium(II) olefin cyclopropanation catalysts.

  Jason A Miller, Bradley A Gross, Michael A Zhuravel, Wiechang Jin, SonBinh T Nguyen
  Angewandte Chemie International Edition 07/2005; 44(25):3885-9. · 13.45 Impact Factor
• Article: The Enantioselective Synthesis of Conformationally Constrained Cyclic - Amino Acids

  Jason A. Miller, SonBinh T. Nguyen
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  ABSTRACT: Enantiomerically pure and conformationally constrained cyclic -amino acids have been the subject of a vast amount of research across the chemical, biological, and medicinal disciplines. These valuable molecules are synthetic precursors for a wide variety of useful compounds that include natural products and modified peptides. Many methods have been developed to prepare chiral cyclic -amino acids in high optical purity. This mini-review will discuss some of the most recent and successful approaches.
  Mini-Reviews in Organic Chemistry 12/2004; 2(1):39-45. · 2.41 Impact Factor
• Article: trans-Cyclopropyl beta-amino acid derivatives via asymmetric cyclopropanation using a (Salen)Ru(II) catalyst.

  Jason A Miller, Edward J Hennessy, Will J Marshall, Mark A Scialdone, SonBinh T Nguyen
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  ABSTRACT: trans-Cyclopropyl beta-amino acid derivatives can be synthesized in five steps with excellent enantioselectivities using a chiral (Salen)Ru(II) cyclopropanation catalyst in the key asymmetry-induction step. This facile synthesis proceeds with high overall yield and can be used to prepare a number of carbamate-protected (Cbz and Boc are demonstrated) beta-amino acid derivatives.
  The Journal of Organic Chemistry 11/2003; 68(20):7884-6. · 4.45 Impact Factor
• Article: New palladium(II)-catalyzed asymmetric 1,2-dibromo synthesis.

  Arab K El-Qisairi, Hanan A Qaseer, George Katsigras, Philip Lorenzi, Unnati Trivedi, Sylvia Tracz, Amy Hartman, Jason A Miller, Patrick M Henry
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  ABSTRACT: [reaction: see text] The oxidation of olefins by chiral monometallic and bimetallic Pd(II)-Cu(II) catalysts in bromide-containing aqueous-THF reaction mixtures produced chiral 1,2-dibromides. With alpha-olefins, the ee's were about 95% while most of the internal alkenes gave somewhat lower enantioselectivities ( approximately 80%).
  Organic Letters 03/2003; 5(4):439-41. · 5.86 Impact Factor
• Article: An efficient and highly enantio- and diastereoselective cyclopropanation of olefins catalyzed by Schiff-base ruthenium(II) complexes.

  Jason A Miller, Wiechang Jin, SonBinh T Nguyen
  Angewandte Chemie International Edition 09/2002; 41(16):2953-6. · 13.45 Impact Factor