Article

Limb salvage in bone sarcomas in patients younger than age 10: a 20-year experience.

Department of Orthopedic, University of Navarra, Pamplona, Spain.
Journal of Pediatric Orthopaedics (impact factor: 1.16). 23(6):753-62. pp.753-62
Source: PubMed

ABSTRACT The authors present their experience over the last 20 years in limb salvage procedures of a consecutive series of 40 children under 10 years of age (range 2-10 years) with bone sarcomas. Nineteen were osteogenic sarcomas and 21 were Ewing sarcomas. Only one case, located in the distal phalanx of the toe, was treated by straightforward amputation. Intercalary allografts and Canadell's technique were used to preserve joints whenever possible, and prosthesis or osteoarticular allografts were used when the joint surface was involved. Survival rate in this series was 75%. There were four local recurrences. At the last follow-up (mean 11.2 years, range 5-19 years postop), 90% of the patients preserved their limbs. Eighty percent of the authors' results were excellent or good according to the Musculoskeletal Tumor Society Scale. Limb salvage is a real possibility even in young children with bone sarcomas. The age of the patient itself is not a contraindication for limb salvage.

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    Article: Surgical modalities in the treatment of bone sarcoma in children.
    Rafiq Abed, Robert Grimer
    [show abstract] [hide abstract]
    ABSTRACT: Primary malignant bone tumours are rare but are one of the most common malignancies in adolescents. The optimum management of a child with a bone tumour is at a specialist treatment centre by a multidisciplinary team experienced in the diagnosis, chemotherapy and surgical management of these conditions. Most tumours are treated with chemotherapy followed by surgery. The surgical aim is to completely resect the tumour whilst ideally preserving the limb and maintaining function. The perfect limb salvage operation that restores normal function with no long term morbidity is rarely possible and most operations will restore function with potential long term complications. The variety of techniques possible for limb salvage includes the use of prostheses, allografts, reimplantation of sterilised bone or use of vascularised bone. Extendible prostheses are now common place and can maintain limb length following tumour resection even in the young child. Assessing outcomes is notoriously difficult but various measures are starting to allow comparisons of long term outcomes for this group of patients.
    Cancer treatment reviews 03/2010; 36(4):342-7. · 5.30 Impact Factor
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Keywords

40 children
 
authors present
 
authors' results
 
bone sarcomas
 
Canadell's technique
 
distal phalanx
 
last 20 years
 
last follow-up
 
limb salvage
 
limb salvage procedures
 
limbs
 
Musculoskeletal Tumor Society Scale
 
patients
 
possible
 
range 2-10 years
 
range 5-19 years postop
 
real possibility
 
straightforward amputation
 
Survival rate
 
young children