Evaluation of the Arthritis Impact Measurement Scales (AIMS2) in Finnish patients with rheumatoid arthritis
ABSTRACT To evaluate the validity and reliability of the Finnish version of the Arthritis Impact Measurement Scales (AIMS2) in Finnish patients with rheumatoid arthritis (RA).
The reliability of the Finnish AIMS2 (Finn-AIMS2) questionnaire was assessed by test retest procedure and internal consistency of health-status scales. Construct validity was assessed by factor analysis, and convergent validity by correlation coefficients, with several disease activity and functional status variables.
Internal consistency was 0.79-0.89 and test retest reliability 0.72-0.97. Factor analysis identified three factors: physical, psychosocial, and pain. There were strong correlations between the Finn-AIMS2 health-status scales and the Health Assessment Questionnaire (HAQ).
The Finn-AIMS2 questionnaire is a reliable and valid instrument for measuring health status in middle-aged Finnish patients with RA. The results also support the applicability of AIMS2 in comparisons in multinational studies.
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ABSTRACT: This study conducted a systematic review of the methodological quality of the psychometric evaluation process and the quality of measurement properties of rheumatoid arthritis (RA)-specific health-related quality-of-life (HRQOL) questionnaires with the purpose of obtaining the best evidence to help in the selection of the most appropriate instrument for measuring HRQOL in RA patients. A systematic literature search was performed to identify RA-specific HRQOL questionnaires in databases. The methodological quality of the studies was assessed using the Consensus-based Standards for the Selection of Health Measurement Instruments checklist. The quality of the measurement properties was assessed using quality criteria. The evidence regarding the measurement properties was pooled using best-evidence synthesis, with considerations of the number and methodological quality of the studies, and the consistency of their findings in terms of the quality of the measurement properties. The search identified 37 studies describing 9 instruments. Best-evidence synthesis suggested that the Rheumatoid Arthritis Quality of Life (RAQoL) questionnaire had the strongest positive evidence, especially with respect to reliability, measurement error, and content validity, and moderate positive evidence with respect to hypothesis testing and responsiveness. The current evidence suggests that the best-validated instrument among the RA-specific HRQOL measures is the RAQoL questionnaire in terms of both methodological quality in the process of psychometric evaluation and the quality of the measurement properties. However, there is limited evidence regarding internal consistency and structural validity of the RAQoL. Further efforts are warranted to establish the psychometric quality of this questionnaire.Quality of Life Research 05/2014; 23(10). DOI:10.1007/s11136-014-0716-6 · 2.86 Impact Factor
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ABSTRACT: Objectives: The aim of this study is to evaluate the measurement properties of the Arthritis Impact Measurement Scales 2 (AIMS2) in Slovak patients with rheumatoid arthritis (RA).Background: RA impacts all aspects of life quality (QoL). Many instruments for QoL in RA patients frequently assess only biological aspects. The AIMS2 instrument covers physical, emotional and social QoL and it is widely and successfully used as an indicator of the outcomes of care for arthritis patients, but not in Slovak RA patients.Methods: After translation 178 patients with RA were asked to complete the AIMS2, Visual Analogue Scale for pain - VAS, Health Assessment Questionnaire Disability Index - HAQ-DI, Beck Anxiety Inventory - BAI and Zung Self-Rating Depression Scale - SDS to analyse the validity of the Slovak-AIMS2. Pearson correlations, one-way analysis of variance (ANOVA), t-test, and principal component analysis were used to test validity of AIMS2. The reliability was assessed by internal consistency, as estimated by Cronbach's alpha coefficients, and using the test-retest procedure. Results: The Cronbach's alpha coefficients for AIMS2 scales ranged from 0.78 to 0.94, the test-retest reliability was significant (p<0.05), ranging from 0.61 to 0.99. The correlations between most of the Slovak-AIMS2 scales and HAQ-DI, VAS, BAI and SDS were statistically significant (p<0.05). The principal component analysis identified three factor models explaining 66.82 % of the variance. Conclusions: The results showed that Slovak-AIMS2 is culturally appropriate, valid and reliable for measuring the health status in adult RA patients (Tab. 6, Ref. 20). Keywords: Arthritis Impact Measurement Scales 2, quality of life in Slovak patients, rheumatoid arthritis.Bratislavske lekarske listy 01/2013; 114(9):534-9. DOI:10.4149/BLL_2013_112 · 0.45 Impact Factor
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ABSTRACT: Introduction Environmental effectors, such as ultraviolet radiation exposure, infection and stress, have been established as having a role in exacerbating lupus symptoms. However, unpredictable patterns of flare events still remain a mystery. Occupational effectors have also been suggested as having a contributing role; however, they are not widely researched. In this paper we report a pilot study designed to generate focus areas for future research regarding occupational exposures and systemic lupus erythematosus (SLE). Methods The study explored potential links between exposures and the occurrence of patient-reported flare events in 80 Australian women with SLE (American College of Rheumatology (ACR) criteria classified). Specifically, the study assessed the hypothesis that occupational exposure is associated with significant changes in the likelihood of lupus flares. Lifetime employment history was analysed with the Finnish Job Exposure Matrix (FINJEM), 40 different semiquantified exposure class estimates for a wide number of occupations based on probability of exposure (p≥5%=exposed) were analysed with the construction of negative binomial regression models to test relationships between occupational agents and flare days. A backward stepwise elimination was used to generate a parsimonious model. Results Significant associations were noted for exposure classes of manual handling burden, (p=0.02, incidence rate ratio (IRR) 1.01), Iron (p=0.00, IRR 1.37), wood dust (p=0.00, IRR 3.34) and asbestos (p=0.03, IRR 2.48). Conclusion Exposure assessment results indicated that occupations, such as nursing, with a high manual handling burden, posed increased risk to patients with SLE, however, the greatest risk was associated with wood dust and iron exposure with teachers and specialist labourers.Science & medicine 04/2014; 1(e000023). DOI:10.1136/lupus-2014-000023