Article

[Non-Hodgkin's lymphoma with protein S deficiency].

Unité d'hémato-oncologie pédiatrique, hôpital d'enfants de Rabat, Maroc.
Archives de Pédiatrie (impact factor: 0.3). 02/2004; 11(1):29-32. pp.29-32
Source: PubMed

ABSTRACT Venous thrombosis is rare in children. It can be either acquired or of constitutional origin. Thrombosis during non-Hodgkin lymphoma remains exceptional and is usually locally associated to the tumoral process, raising the issue of its tumoral or cruoric nature. The treatment is based on anticoagulation concomitantly to chemotherapy. We report on a 4-year-old boy admitted for mediastinal non-Hodgkin lymphoma, who developed a thrombosis of the superior vena cava associated to protein S-deficiency. The mechanism of thrombosis may have been multifactorial: associated protein S-deficiency, vascular compression, tumoral process and chemotherapy.

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Keywords

4-year-old boy
 
anticoagulation concomitantly
 
constitutional origin
 
cruoric nature
 
mediastinal non-Hodgkin lymphoma
 
non-Hodgkin lymphoma
 
protein S-deficiency
 
superior vena cava
 
tumoral
 
tumoral process
 
vascular compression
 

M El Kababri