Alveolar soft part sarcoma: a unique tumor with disputed histogenesis.
- MedGenMed: Medscape general medicine 02/2006; 8(3):2.
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ABSTRACT: Aim: To study the clinico-radiological and clinic-pathological features of orbital alveolar soft-part sarcomas (ASPS). Materials and Methods: We retrieved 9 cases of orbital ASPS. Histopathological and immunohistochemical features and clinico-radiological findings were evaluated. Results: Age at presentation varied from 1 to 31 years. Both, children and adults were affected. Proptosis was the most common clinical presentation. PAS-positive diastase-resistant crystals and granules were found in all cases. All patients received adjuvant radiotherapy. Two cases had positive surgical margins and were treated with additional adjuvant chemotherapy. None of the patients had recurrence or metastases till the last follow up. Conclusion: Early diagnosis with a multidisciplinary, multimodal approach of treatment is quintessential in achieving a long disease-free survival in patients with ASPS.Journal of Cancer Research and Therapeutics 04/2014; 10(2):294-8. DOI:10.4103/0973-1482.136570 · 0.95 Impact Factor
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