Article

OLAV-PMF: a novel scoring scheme for high-throughput peptide mass fingerprinting.

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Journal of Proteome Research (impact factor: 5.11). 3(1):55-60. pp.55-60
Source: PubMed

ABSTRACT We propose a new type of probabilistic scoring scheme framework for protein identification from peptide masses. We first introduce the framework itself and explain its requirements. In a second part, we describe a particular implementation and test it on a data set of more than 8000 MALDI-TOF spectra with known contents. Doing so, we also compare its performance to two widely used scoring schemes, thereby demonstrating the potential of the proposed approach.

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Keywords

8000 MALDI-TOF spectra
 
particular implementation
 
probabilistic
 
proposed approach
 
protein identification
 
second part