Article

Successful minimally invasive management of late portal vein thrombosis after splenectomy due to splenic artery steal syndrome following liver transplantation: a case report.

Department of Surgery and Transplantation Unit, University of Udine, Udine, Italy.
Transplantation Proceedings (impact factor: 1). 05/2004; 36(3):558-9. DOI:10.1016/j.transproceed.2004.02.040 pp.558-9
Source: PubMed

ABSTRACT Portal vein thrombosis (PVT) after liver transplantation (OLT), which occurs in 1% to 2.7% of cases, can compromise patient and graft survival. Percutaneous transhepatic portal vein angioplasty offers an option to treat PVT, diminishing surgically related morbidity and the need for retransplantation. We describe a case of late PVT after OLT, which was successfully treated by a minimally invasive percutaneous transhepatic approach using both mechanical fragmentation and pharmacologic lysis of the thrombus followed by anticoagulation. The patient has had a good clinical course with normal graft function and patent portal blood flow at 6-month follow-up. This case report confirms the possibility of successful recanalization of the portal vein in a patient with late PVT after liver transplantation. Sustained anticoagulation/antiaggregation therapy for at least 6 months after the procedure is advisable.

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Keywords

anticoagulation
 
case report
 
compromise patient
 
good clinical course
 
graft survival
 
liver transplantation
 
mechanical fragmentation
 
minimally invasive percutaneous transhepatic approach
 
OLT
 
patent portal blood flow
 
Percutaneous transhepatic portal vein angioplasty
 
portal vein
 
Portal vein thrombosis
 
PVT
 
retransplantation
 
Sustained anticoagulation/antiaggregation therapy